BAA06271.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,986 Da
NCBI Official Full Name
cationic amino acid transporter 2
NCBI Official Synonym Full Names
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
NCBI Protein Information
cationic amino acid transporter 2
UniProt Protein Name
Cationic amino acid transporter 2
UniProt Synonym Protein Names
Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2
UniProt Synonym Gene Names
UniProt Entry Name
CTR2_HUMAN
NCBI Summary for CAT2
The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Comments for CAT2
SLC7A2: Low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). Plays a regulatory role in classical or alternative activation of macrophages. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 8p22
Cellular Component: membrane; integral to plasma membrane; plasma membrane
Molecular Function: high affinity arginine transmembrane transporter activity; high affinity lysine transmembrane transporter activity; basic amino acid transmembrane transporter activity
Biological Process: amino acid metabolic process; macrophage activation; transport; amino acid transport; regulation of macrophage activation; production of nitric oxide during acute inflammatory response; regulation of inflammatory response; ion transport; nitric oxide biosynthetic process; transmembrane transport
Research Articles on CAT2
Precautions
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Pathways associated with CAT2 elisa kit
Diseases associated with CAT2 elisa kit
Organs/Tissues associated with CAT2 elisa kit
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