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CD40L elisa kit :: Rat Cd 40 Ligand ELISA Kit

Scan QR to view Datasheet Catalog #    MBS024860 CD40L elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cd 40 Ligand (CD40L), ELISA Kit

 Also Known As   

Rat Cd 40 Ligand ELISA Kit

 Product Gene Name   

CD40L elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: X; NC_000023.10 (135730336..135742549). Location: Xq26
 OMIM    300386
 3D Structure    ModBase 3D Structure for P29965
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 Species Reactivity    Rat
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CD40L elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CD40L purchase    MBS024860 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cd 40 Ligand (CD40L) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CD40L. The ELISA analytical biochemical technique of the MBS024860 kit is based on CD40L antibody-CD40L antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CD40L antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CD40L. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CD40L. It may not necessarily be applicable to this product.
 NCBI GI #    4557433
 NCBI GeneID    959
 NCBI Accession #    NP_000065.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000074.2 [Other Products]
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 UniProt Primary Accession #    P29965 [Other Products]
 UniProt Related Accession #    P29965 [Other Products]
 Molecular Weight    29,274 Da
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 NCBI Official Full Name    CD40 ligand
 NCBI Official Synonym Full Names    CD40 ligand
 NCBI Official Symbol    CD40LG [Similar Products]
 NCBI Official Synonym Symbols   
IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
[Similar Products]
 NCBI Protein Information    CD40 ligand; CD40-L; CD40 antigen ligand; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5
 UniProt Protein Name    CD40 ligand
 UniProt Synonym Protein Names   
T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5
 UniProt Gene Name    CD40LG [Similar Products]
 UniProt Synonym Gene Names    CD40L; TNFSF5; TRAP; CD40-L; TRAP [Similar Products]
 UniProt Entry Name    CD40L_HUMAN
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 NCBI Summary for CD40L    The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD40L    CD40LG: Mediates B-cell proliferation in the absence of co- stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Defects in CD40LG are the cause of X-linked immunodeficiency with hyper-IgM type 1 (HIGM1); also known as X-linked hyper IgM syndrome (XHIM). HIGM1 is an immunoglobulin isotype switch defect characterized by elevated concentrations of serum IgM and decreased amounts of all other isotypes. Affected males present at an early age (usually within the first year of life) recurrent bacterial and opportunistic infections, including Pneumocystis carinii pneumonia and intractable diarrhea due to cryptosporidium infection. Despite substitution treatment with intravenous immunoglobulin, the overall prognosis is rather poor, with a death rate of about 10% before adolescence. Belongs to the tumor necrosis factor family.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq26

Cellular Component: extracellular space; integral to plasma membrane; plasma membrane; integral to membrane; external side of plasma membrane

Molecular Function: cytokine activity; CD40 receptor binding; tumor necrosis factor receptor binding

Biological Process: B cell proliferation; platelet activation; leukocyte adhesion; regulation of immune response; positive regulation of interleukin-12 production; immunoglobulin secretion; B cell differentiation; isotype switching; inflammatory response; regulation of immunoglobulin secretion; negative regulation of apoptosis

Disease: Immunodeficiency With Hyper-igm, Type 1
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 Research Articles on CD40L    1. Suppression of CD154 expression is a surrogate for suppression of proliferation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CD40L elisa kitPathways associated with CD40L elisa kit
 Reference Product  PubMed Publications
 CD40 elisa kit  >20 publications with CD40L and CD40
 ICAM1 elisa kit  >3 publications with CD40L and ICAM1
 CD86 elisa kit  >3 publications with CD40L and CD86
 TRAF1 elisa kit  >2 publications with CD40L and TRAF1
 RELA elisa kit  >1 publications with CD40L and RELA
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 CD40/CD40L Signaling Pathway antibodies  CD40/CD40L Signaling Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Signaling In The CD4+ TCR Pathway antibodies  Calcium Signaling In The CD4+ TCR Pathway Diagram
Diseases associated with CD40L elisa kitOrgans/Tissues associated with CD40L elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >9 publications with CD40L and Inflammation
 Neoplasms Antibodies  >7 publications with CD40L and Neoplasms
 Necrosis Antibodies  >6 publications with CD40L and Necrosis
 Myocardial Infarction Antibodies  >3 publications with CD40L and Myocardial Infarction
 Myocardial Ischemia Antibodies  >3 publications with CD40L and Myocardial Ischemia
 Cardiovascular Diseases Antibodies  >3 publications with CD40L and Cardiovascular Diseases
 Heart Diseases Antibodies  >3 publications with CD40L and Heart Diseases
 Kidney Diseases Antibodies  >2 publications with CD40L and Kidney Diseases
 Hypersensitivity Antibodies  >2 publications with CD40L and Hypersensitivity
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >25 publications with CD40L and Blood
 Mixed Antibodies  >1 publications with CD40L and Mixed
 Thymus Antibodies  >1 publications with CD40L and Thymus
 Brain Antibodies  >1 publications with CD40L and Brain
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