NP_036961.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
12,841 Da
NCBI Official Full Name
cholecystokinin preproprotein
NCBI Official Synonym Full Names
cholecystokinin
NCBI Protein Information
cholecystokinin
UniProt Protein Name
Cholecystokinin
UniProt Synonym Gene Names
UniProt Entry Name
CCKN_RAT
NCBI Summary for CCK-8
brain-gut peptide with hemacrine and autocrine function in the gut [RGD, Feb 2006]
UniProt Comments for CCK-8
Function: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Subunit structure: Binds to CCK-A receptors in the pancreas and CCK-B receptors in the brain
By similarity.
Subcellular location: Secreted.
Tissue specificity: The shortest form (CCK8) is predominantly found in the brain, whereas the larger ones are found in the intestine.
Post-translational modification: The precursor is cleaved by proteases to produce a number of active cholecystokinins.Sulfation of Tyr-97 is essential for receptor activation.
Sequence similarities: Belongs to the gastrin/cholecystokinin family.
Research Articles on CCK-8
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Products associated with CCK-8 elisa kit
Pathways associated with CCK-8 elisa kit
Diseases associated with CCK-8 elisa kit
Organs/Tissues associated with CCK-8 elisa kit
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