AAA53094.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
12,669 Da
NCBI Official Full Name
cholecystokinin
NCBI Official Synonym Full Names
cholecystokinin
NCBI Protein Information
cholecystokinin; prepro-cholecystokinin; cholecystokinin triacontatriapeptide
UniProt Protein Name
Cholecystokinin
UniProt Synonym Protein Names
(1-49)-CCK58
UniProt Synonym Gene Names
CCK; CCK58; CCK39; CCK33; CCK25; CCK18; CCK12; CCK8; CCK7; CCK5 [Similar Products]
UniProt Entry Name
CCKN_HUMAN
NCBI Summary for CCK
Cholecystokinin is a brain/gut peptide. In the gut, it induces the release of pancreatic enzymes and the contraction of the gallbladder. In the brain, its physiologic role is unclear. The cholecystokinin pro-hormone is processed by endo- and exo-proteolytic cleavages. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
UniProt Comments for CCK
CCK: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. Belongs to the gastrin/cholecystokinin family.
Protein type: Secreted; Cell development/differentiation; Secreted, signal peptide; Hormone
Chromosomal Location of Human Ortholog: 3p22.1
Cellular Component: axon hillock; extracellular space; axon; dendrite; extracellular region; terminal button; perikaryon
Molecular Function: neuropeptide hormone activity; protein binding; hormone activity
Biological Process: caspase activation; positive regulation of protein oligomerization; release of cytochrome c from mitochondria; positive regulation of peptidyl-tyrosine phosphorylation; behavioral fear response; axonogenesis; positive regulation of mitochondrial depolarization; eating behavior; protein kinase C activation; positive regulation of cell proliferation; neuron migration; regulation of sensory perception of pain; signal transduction; negative regulation of appetite
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Products associated with CCK elisa kit
Pathways associated with CCK elisa kit
Diseases associated with CCK elisa kit
Organs/Tissues associated with CCK elisa kit
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