AAQ19269.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,769 Da
NCBI Official Full Name
C1 inhibitor mutant, partial
NCBI Official Synonym Full Names
serpin family G member 1
NCBI Protein Information
plasma protease C1 inhibitor
UniProt Protein Name
Plasma protease C1 inhibitor
UniProt Synonym Protein Names
C1 esterase inhibitor; C1-inhibiting factor; Serpin G1
UniProt Synonym Gene Names
NCBI Summary for C1INH
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, Jul 2008]
UniProt Comments for C1INH
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.
Research Articles on C1INH
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Products associated with C1INH elisa kit
Pathways associated with C1INH elisa kit
Diseases associated with C1INH elisa kit
Organs/Tissues associated with C1INH elisa kit
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