NP_036673.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,259 Da
NCBI Official Full Name
cytochrome P450 1A2
NCBI Official Synonym Full Names
cytochrome P450, family 1, subfamily a, polypeptide 2
NCBI Protein Information
cytochrome P450 1A2
UniProt Protein Name
Cytochrome P450 1A2
UniProt Synonym Protein Names
CYPIA2; Cholesterol 25-hydroxylase
UniProt Synonym Gene Names
NCBI Summary for Cyp1a2
a monooxygenase that may play a role in xenobiotic metabolism [RGD, Feb 2006]
UniProt Comments for Cyp1a2
CYP1A2: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation (By similarity)
Protein type: Amino Acid Metabolism - tryptophan; Cofactor and Vitamin Metabolism - retinol; EC 1.14.14.1; Lipid Metabolism - linoleic acid; Oxidoreductase; Secondary Metabolites Metabolism - caffeine; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 8q24
Cellular Component: intracellular membrane-bound organelle
Molecular Function: demethylase activity; enzyme binding; heme binding; monooxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Biological Process: alkaloid metabolic process; aromatic compound metabolic process; cellular respiration; dibenzo-p-dioxin metabolic process; drug catabolic process; drug metabolic process; exogenous drug catabolic process; heterocycle metabolic process; hydrogen peroxide biosynthetic process; lung development; monocarboxylic acid metabolic process; monoterpenoid metabolic process; porphyrin metabolic process; post-embryonic development; regulation of gene expression; response to drug; response to estradiol stimulus; response to lipopolysaccharide; response to organic cyclic substance; response to organic substance; steroid catabolic process; toxin biosynthetic process; toxin metabolic process; xenobiotic metabolic process
Research Articles on Cyp1a2
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Products associated with Cyp1a2 elisa kit
Pathways associated with Cyp1a2 elisa kit
Diseases associated with Cyp1a2 elisa kit
Organs/Tissues associated with Cyp1a2 elisa kit
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