AAB21814.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
76,690 Da
NCBI Official Full Name
cytochrome P450 reductase, partial
NCBI Official Synonym Full Names
cytochrome p450 oxidoreductase
NCBI Protein Information
NADPH--cytochrome P450 reductase
UniProt Protein Name
NADPH--cytochrome P450 reductase
UniProt Synonym Gene Names
NCBI Summary for CPR
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for CPR
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
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Products associated with CPR elisa kit
Pathways associated with CPR elisa kit
Diseases associated with CPR elisa kit
Organs/Tissues associated with CPR elisa kit
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