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DRD1 elisa kit :: Rat DRD1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2508311
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DRD1, ELISA Kit

★Popular Item★
 Also Known As   

Rat DRD1 (Dopamine Receptor D1) ELISA Kit

 Product Gene Name   

DRD1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    126449
 3D Structure    ModBase 3D Structure for P21728
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Rat DRD1. No significant cross-reactivity or interference between Rat DRD1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat DRD1 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    12.5--800ng/mL
 Sensitivity    7.5ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DRD1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DRD1 purchase    MBS2508311 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the DRD1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 12.5--800ng/mL in biological research samples containing DRD1, with an estimated sensitivity of 7.5ng/mL. The ELISA analytical biochemical technique of the MBS2508311 kit is based on DRD1 antibody-DRD1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DRD1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DRD1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for DRD1 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of DRD1 in Rat serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat DRD1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat DRD1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat DRD1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat DRD1. You can calculate the concentration of Rat DRD1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of DRD1 elisa kit    DRD1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2508311. Click to request current manual
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NCBI/Uniprot data below describe general gene information for DRD1. It may not necessarily be applicable to this product.
 NCBI GI #    4503383
 NCBI GeneID    1812
 NCBI Accession #    NP_000785.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000794.3 [Other Products]
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 UniProt Primary Accession #    P21728 [Other Products]
 UniProt Secondary Accession #    Q4QRJ0; B2RA44 [Other Products]
 UniProt Related Accession #    P21728 [Other Products]
 Molecular Weight    49,293 Da
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 NCBI Official Full Name    D(1A) dopamine receptor
 NCBI Official Synonym Full Names    dopamine receptor D1
 NCBI Official Symbol    DRD1 [Similar Products]
 NCBI Official Synonym Symbols   
DADR; DRD1A
[Similar Products]
 NCBI Protein Information    D(1A) dopamine receptor; D(1A) dopamine receptor; dopamine D1 receptor
 UniProt Protein Name    D(1A) dopamine receptor
 UniProt Synonym Protein Names   
Dopamine D1 receptor
 Protein Family    D(1A) dopamine receptor
 UniProt Gene Name    DRD1 [Similar Products]
 UniProt Entry Name    DRD1_HUMAN
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 NCBI Summary for DRD1    This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for DRD1    DRD1: a G-protein coupled receptor.One of the five types (D1 to D5) of receptors for dopamine. The most abundant dopamine receptor in the central nervous system. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Interacts with calcyon.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 5q35.1

Cellular Component: endoplasmic reticulum membrane; integral to plasma membrane; plasma membrane; nucleus

Molecular Function: protein binding; dopamine receptor activity; dopamine binding; dopamine D1 receptor-like receptor activity

Biological Process: synaptic transmission, dopaminergic; peristalsis; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); behavioral fear response; prepulse inhibition; positive regulation of potassium ion transport; generation of action potential; thermoregulation; G-protein signaling, adenylate cyclase activating pathway; dopamine metabolic process; positive regulation of synaptic transmission, glutamatergic; vasodilation; adult walking behavior; synaptogenesis; behavioral response to cocaine; protein import into nucleus; conditioned taste aversion; positive regulation of cAMP biosynthetic process; visual learning; dopamine receptor, adenylate cyclase activating pathway; grooming behavior; response to drug; dopamine transport; dentate gyrus development; cerebral cortex GABAergic interneuron migration; striatum development; maternal behavior; response to amphetamine; adenylate cyclase activation; regulation of dopamine metabolic process; regulation of dopamine uptake; mating behavior; transmission of nerve impulse; astrocyte development; memory; G-protein signaling, coupled to cyclic nucleotide second messenger; habituation; glucose import; sensitization; operant conditioning; positive regulation of release of sequestered calcium ion into cytosol; dopamine receptor, phospholipase C activating pathway; positive regulation of cell migration
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 Research Articles on DRD1    1. Constitutive D1R differs from D5R in that it fails to drive expression CRE-regulated genes. Treatment of a D1R line with cis-flupentixol induced up-regulation of Na,K-ATPase-alpha2, NHE-2 and NHE-3 mRNA levels.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DRD1 elisa kitPathways associated with DRD1 elisa kit
 Reference Product  PubMed Publications
 ADORA2A elisa kit  >2 publications with DRD1 and ADORA2A
 GNAS elisa kit  >1 publications with DRD1 and GNAS
 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
Diseases associated with DRD1 elisa kitOrgans/Tissues associated with DRD1 elisa kit
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >110 publications with DRD1 and Mental Disorders
 Schizophrenia Antibodies  >47 publications with DRD1 and Schizophrenia
 Nervous System Diseases Antibodies  >34 publications with DRD1 and Nervous System Diseases
 Substance-Related Disorders Antibodies  >32 publications with DRD1 and Substance-Related Disorders
 Brain Diseases Antibodies  >28 publications with DRD1 and Brain Diseases
 Bipolar Disorder Antibodies  >21 publications with DRD1 and Bipolar Disorder
 Movement Disorders Antibodies  >15 publications with DRD1 and Movement Disorders
 Hypertension Antibodies  >12 publications with DRD1 and Hypertension
 Depressive Disorder Antibodies  >11 publications with DRD1 and Depressive Disorder
 Basal Ganglia Diseases Antibodies  >10 publications with DRD1 and Basal Ganglia Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >99 publications with DRD1 and Brain
 Eye Antibodies  >2 publications with DRD1 and Eye
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