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DT elisa kit :: Rat Dopachrome Tautomerase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS015127 DT elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Dopachrome Tautomerase (DT), ELISA Kit

 Also Known As   

Rat Dopachrome Tautomerase ELISA Kit

 Product Gene Name   

DT elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 13; NC_000013.10 (95091835..95131936, complement). Location: 13q32
 OMIM    191275
 3D Structure    ModBase 3D Structure for P40126
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 Species Reactivity    Rat
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DT elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DT purchase    MBS015127 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Dopachrome Tautomerase (DT) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DT. The ELISA analytical biochemical technique of the MBS015127 kit is based on DT antibody-DT antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DT antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DT. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for DT. It may not necessarily be applicable to this product.
 NCBI GI #    1050251
 NCBI GeneID    1638
 NCBI Accession #    AAC41925.1 [Other Products]
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 UniProt Primary Accession #    P40126 [Other Products]
 UniProt Secondary Accession #    Q09GT4 [Other Products]
 UniProt Related Accession #    P40126 [Other Products]
 Molecular Weight    59,145 Da
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 NCBI Official Full Name    dopachrome tautomerase, partial
 NCBI Official Synonym Full Names    dopachrome tautomerase
 NCBI Official Symbol    DCT [Similar Products]
 NCBI Official Synonym Symbols   
TRP-2; TYRP2
[Similar Products]
 NCBI Protein Information    L-dopachrome tautomerase; DT; TRP2; dopachrome delta-isomerase; tyrosine-related protein 2; L-dopachrome Delta-isomerase; tyrosinase-related protein 2; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)
 UniProt Protein Name    L-dopachrome tautomerase
 UniProt Synonym Protein Names   
L-dopachrome Delta-isomerase; Tyrosinase-related protein 2
 UniProt Gene Name    DCT [Similar Products]
 UniProt Synonym Gene Names    TYRP2; DCT; DT; TRP-2; TRP2 [Similar Products]
 UniProt Entry Name    TYRP2_HUMAN
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 UniProt Comments for DT    DCT: Involved in regulating eumelanin and phaeomelanin levels. Belongs to the tyrosinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Isomerase; Amino Acid Metabolism - tyrosine; Membrane protein, integral; EC 5.3.3.12; Cell development/differentiation

Chromosomal Location of Human Ortholog: 13q32

Cellular Component: melanosome membrane; melanosome; integral to membrane; cytosol

Molecular Function: copper ion binding; dopachrome isomerase activity; oxidoreductase activity

Biological Process: neuroblast division in the ventricular zone; positive regulation of neuroblast proliferation; epidermis development; pigmentation during development; melanin biosynthetic process from tyrosine; cell development
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 Research Articles on DT    1. The results suggested that the miRNAs may be involved in MITF regulation of TYR, TYRP1 and TYRP2, which provides a new clue for understanding the role of miRNAs in melanocyte dysfunctional disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DT elisa kitPathways associated with DT elisa kit
 Reference Product  PubMed Publications
 TYRP1 elisa kit  >62 publications with DT and TYRP1
 MITF elisa kit  >48 publications with DT and MITF
 SILV elisa kit  >4 publications with DT and SILV
 MLANA elisa kit  >2 publications with DT and MLANA
 OTX2 elisa kit  >2 publications with DT and OTX2
 SOX9 elisa kit  >1 publications with DT and SOX9
 Products by Pathway  Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
 Tyrosine Metabolism Pathway antibodies  Tyrosine Metabolism Pathway Diagram
 Tyrosine Metabolism Pathway antibodies  Tyrosine Metabolism Pathway Diagram
Diseases associated with DT elisa kitOrgans/Tissues associated with DT elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >133 publications with DT and Neoplasms
 Hypertension Antibodies  >68 publications with DT and Hypertension
 Kidney Diseases Antibodies  >47 publications with DT and Kidney Diseases
 Carcinoma Antibodies  >45 publications with DT and Carcinoma
 Heart Diseases Antibodies  >39 publications with DT and Heart Diseases
 Drug Toxicity Antibodies  >32 publications with DT and Drug Toxicity
 Neoplasms, Experimental Antibodies  >31 publications with DT and Neoplasms, Experimental
 Adenocarcinoma Antibodies  >23 publications with DT and Adenocarcinoma
 Lung Neoplasms Antibodies  >16 publications with DT and Lung Neoplasms
 Necrosis Antibodies  >16 publications with DT and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >260 publications with DT and Kidney
 Eye Antibodies  >145 publications with DT and Eye
 Skin Antibodies  >74 publications with DT and Skin
 Heart Antibodies  >63 publications with DT and Heart
 Brain Antibodies  >58 publications with DT and Brain
 Bone Antibodies  >38 publications with DT and Bone
 Lung Antibodies  >33 publications with DT and Lung
 Embryonic Tissue Antibodies  >20 publications with DT and Embryonic Tissue
 Intestine Antibodies  >13 publications with DT and Intestine
 Connective Tissue Antibodies  >12 publications with DT and Connective Tissue
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