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EPCR elisa kit :: Rat EPCR ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2514218
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EPCR, ELISA Kit

★Popular Item★
 Also Known As   

Rat EPCR(Endothelial Protein C Receptor)ELISA Kit

 Product Gene Name   

EPCR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600646
 3D Structure    ModBase 3D Structure for Q9UNN8
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Rat EPCR. No significant cross-reactivity or interference between Rat EPCR and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat EPCR and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156--10ng/mL
 Sensitivity    0.094ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of EPCR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for EPCR purchase    MBS2514218 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the EPCR, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156--10ng/mL in biological research samples containing EPCR, with an estimated sensitivity of 0.094ng/mL. The ELISA analytical biochemical technique of the MBS2514218 kit is based on EPCR antibody-EPCR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EPCR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EPCR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for EPCR elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of EPCR in Rat serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat EPCR. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat EPCR and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat EPCR, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat EPCR. You can calculate the concentration of Rat EPCR in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of EPCR elisa kit    EPCR elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2514218. Click to request current manual
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NCBI/Uniprot data below describe general gene information for EPCR. It may not necessarily be applicable to this product.
 NCBI GI #    34335272
 NCBI GeneID    10544
 NCBI Accession #    NP_006395.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006404.4 [Other Products]
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 UniProt Primary Accession #    Q9UNN8 [Other Products]
 UniProt Secondary Accession #    Q14218; Q6IB56; Q96CB3; Q9ULX1; B2RC04 [Other Products]
 UniProt Related Accession #    Q9UNN8 [Other Products]
 Molecular Weight    26,671 Da
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 NCBI Official Full Name    endothelial protein C receptor
 NCBI Official Synonym Full Names    protein C receptor, endothelial
 NCBI Official Symbol    PROCR [Similar Products]
 NCBI Official Synonym Symbols   
CCCA; EPCR; CCD41
[Similar Products]
 NCBI Protein Information    endothelial protein C receptor; APC receptor; CD201 antigen; activated protein C receptor; cell cycle, centrosome-associated protein; centrocyclin
 UniProt Protein Name    Endothelial protein C receptor
 UniProt Synonym Protein Names   
Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD_antigen: CD201
 UniProt Gene Name    PROCR [Similar Products]
 UniProt Synonym Gene Names    EPCR; APC receptor [Similar Products]
 UniProt Entry Name    EPCR_HUMAN
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 NCBI Summary for EPCR    The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]
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 UniProt Comments for EPCR    EPCR: a single-pass type I membrane protein. Binds activated protein C (APC), a serine protease that regulates thrombin (IIa) production. Plays a pivotal role in preventing blood coagulation through binding of activated protein C. Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. The binding of APC to EPCR and PAR-1 increases invasion and chemotaxis.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 20q11.2

Cellular Component: centrosome; focal adhesion; cell surface; integral to plasma membrane; extracellular region; plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: antigen processing and presentation; immune response; blood coagulation; negative regulation of coagulation; leukocyte migration
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 Research Articles on EPCR    1. Piperlonguminine might have potential as an anti-sEPCR shedding reagent against PMA-mediated EPCR shedding.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with EPCR elisa kitPathways associated with EPCR elisa kit
 Reference Product  PubMed Publications
 APC elisa kit  >77 publications with EPCR and APC
 PROC elisa kit  >8 publications with EPCR and PROC
 THBD elisa kit  >8 publications with EPCR and THBD
 CCL2 elisa kit  >3 publications with EPCR and CCL2
 CAV1 elisa kit  >3 publications with EPCR and CAV1
 F2R elisa kit  >2 publications with EPCR and F2R
 F2RL1 elisa kit  >1 publications with EPCR and F2RL1
 Products by Pathway  Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Common Pathway antibodies  Common Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with EPCR elisa kitOrgans/Tissues associated with EPCR elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >83 publications with EPCR and Inflammation
 Necrosis Antibodies  >34 publications with EPCR and Necrosis
 Nervous System Diseases Antibodies  >22 publications with EPCR and Nervous System Diseases
 Disease Models, Animal Antibodies  >14 publications with EPCR and Disease Models, Animal
 Heart Diseases Antibodies  >12 publications with EPCR and Heart Diseases
 Breast Neoplasms Antibodies  >9 publications with EPCR and Breast Neoplasms
 Kidney Diseases Antibodies  >8 publications with EPCR and Kidney Diseases
 Hemorrhage Antibodies  >7 publications with EPCR and Hemorrhage
 Lung Neoplasms Antibodies  >5 publications with EPCR and Lung Neoplasms
 Liver Diseases Antibodies  >4 publications with EPCR and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >161 publications with EPCR and Blood
 Vascular Antibodies  >113 publications with EPCR and Vascular
 Lung Antibodies  >21 publications with EPCR and Lung
 Brain Antibodies  >13 publications with EPCR and Brain
 Bone Antibodies  >12 publications with EPCR and Bone
 Heart Antibodies  >11 publications with EPCR and Heart
 Kidney Antibodies  >10 publications with EPCR and Kidney
 Muscle Antibodies  >10 publications with EPCR and Muscle
 Embryonic Tissue Antibodies  >9 publications with EPCR and Embryonic Tissue
 Umbilical Cord Antibodies  >9 publications with EPCR and Umbilical Cord
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