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EIF4E elisa kit :: Rat Eukaryotic Translation Initiation Factor 4E (EIF4E) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9352700 EIF4E elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Eukaryotic Translation Initiation Factor 4E (EIF4E), ELISA Kit

★Popular Item★
 Also Known As   

Rat Eukaryotic Translation Initiation Factor 4E (EIF4E) ELISA Kit

 Product Gene Name   

EIF4E elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Species Reactivity    Rat
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    62.5 pg/ml - 2000 pg/ml
 Sensitivity    10 pg/ml
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of EIF4E elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for EIF4E purchase    MBS9352700 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Eukaryotic Translation Initiation Factor 4E (EIF4E) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5 pg/ml - 2000 pg/ml in biological research samples containing EIF4E, with an estimated sensitivity of 10 pg/ml. The ELISA analytical biochemical technique of the MBS9352700 kit is based on EIF4E antibody-EIF4E antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EIF4E antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EIF4E. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for EIF4E elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EIF4E (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9352700. Click to request current manual
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NCBI/Uniprot data below describe general gene information for EIF4E. It may not necessarily be applicable to this product.
 NCBI GI #    16758870
 NCBI GeneID    117045
 NCBI Accession #    NP_446426.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_053974.2 [Other Products]
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 UniProt Secondary Accession #    P20415 [Other Products]
 UniProt Related Accession #    P63074 [Other Products]
 Molecular Weight    25,053 Da
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 NCBI Official Full Name    eukaryotic translation initiation factor 4E
 NCBI Official Synonym Full Names    eukaryotic translation initiation factor 4E
 NCBI Official Symbol    Eif4e [Similar Products]
 NCBI Protein Information    eukaryotic translation initiation factor 4E
 UniProt Protein Name    Eukaryotic translation initiation factor 4E
 UniProt Synonym Protein Names   
eIF-4F 25 kDa subunit; mRNA cap-binding protein
 Protein Family    Eukaryotic translation initiation factor
 UniProt Gene Name    Eif4e [Similar Products]
 UniProt Synonym Gene Names    eIF-4E; eIF4E [Similar Products]
 UniProt Entry Name    IF4E_RAT
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 NCBI Summary for EIF4E    binds to the mRNA 7-methylguanosine cap and mediates mRNA binding to the 40S ribosome in the rate limiting step in translational initiation [RGD, Feb 2006]
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 UniProt Comments for EIF4E    EIF4E: a protein of the eukaryotic initiation factor 4E family. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the EIF4F complex.

Protein type: Translation initiation; Translation

Cellular Component: cytoplasm; eukaryotic translation initiation factor 4F complex; mRNA cap complex; perinuclear region of cytoplasm; protein complex; stress granule

Molecular Function: enzyme binding; eukaryotic initiation factor 4G binding; protein binding; translation initiation factor activity

Biological Process: behavioral fear response; G1/S transition of mitotic cell cycle; lung development; negative regulation of neuron differentiation; negative regulation of translation; positive regulation of mitotic cell cycle; regulation of translation; stem cell maintenance; translational initiation
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 Research Articles on EIF4E    1. Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, resulting in caspase-dependent and -independent apoptosis in neuronal cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with EIF4E elisa kitPathways associated with EIF4E elisa kit
 Reference Product  PubMed Publications
 Mtor elisa kit  >855 publications with EIF4E and Mtor
 Eif4ebp1 elisa kit  >555 publications with EIF4E and Eif4ebp1
 Eif4ebp2 elisa kit  >55 publications with EIF4E and Eif4ebp2
 Eif4g1 elisa kit  >52 publications with EIF4E and Eif4g1
 Rps6 elisa kit  >50 publications with EIF4E and Rps6
 Eif4a1 elisa kit  >7 publications with EIF4E and Eif4a1
 Eif4g3 elisa kit  >6 publications with EIF4E and Eif4g3
 Ncbp1 elisa kit  >1 publications with EIF4E and Ncbp1
 Eif4a2 elisa kit  >1 publications with EIF4E and Eif4a2
 Eif4a3 elisa kit  >1 publications with EIF4E and Eif4a3
 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies  Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Deadenylation Of MRNA Pathway antibodies  Deadenylation Of MRNA Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
Diseases associated with EIF4E elisa kitOrgans/Tissues associated with EIF4E elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >254 publications with EIF4E and Carcinoma
 Breast Neoplasms Antibodies  >123 publications with EIF4E and Breast Neoplasms
 Adenocarcinoma Antibodies  >100 publications with EIF4E and Adenocarcinoma
 Necrosis Antibodies  >69 publications with EIF4E and Necrosis
 Disease Models, Animal Antibodies  >66 publications with EIF4E and Disease Models, Animal
 Hypertrophy Antibodies  >64 publications with EIF4E and Hypertrophy
 Neoplasm Metastasis Antibodies  >62 publications with EIF4E and Neoplasm Metastasis
 Cardiovascular Diseases Antibodies  >61 publications with EIF4E and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >58 publications with EIF4E and Neoplasms, Experimental
 Brain Diseases Antibodies  >51 publications with EIF4E and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >158 publications with EIF4E and Brain
 Liver Antibodies  >155 publications with EIF4E and Liver
 Lung Antibodies  >108 publications with EIF4E and Lung
 Heart Antibodies  >99 publications with EIF4E and Heart
 Kidney Antibodies  >78 publications with EIF4E and Kidney
 Pancreas Antibodies  >42 publications with EIF4E and Pancreas
 Prostate Antibodies  >37 publications with EIF4E and Prostate
 Ovary Antibodies  >36 publications with EIF4E and Ovary
 Embryonic Tissue Antibodies  >29 publications with EIF4E and Embryonic Tissue
 Eye Antibodies  >22 publications with EIF4E and Eye
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