NP_005121.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,264 Da
NCBI Official Full Name
fibroblast growth factor-binding protein 1
NCBI Official Synonym Full Names
fibroblast growth factor binding protein 1
NCBI Official Synonym Symbols
FGFBP; HBP17; FGF-BP; FGF-BP1; FGFBP-1 [Similar Products]
NCBI Protein Information
fibroblast growth factor-binding protein 1; FGF-binding protein 1; 17 kDa HBGF-binding protein; heparin-binding growth factor binding protein; 17 kDa heparin-binding growth factor-binding protein
UniProt Protein Name
Fibroblast growth factor-binding protein 1
UniProt Synonym Protein Names
17 kDa heparin-binding growth factor-binding protein
UniProt Synonym Gene Names
FGFBP; HBP17; FGF-BP; FGF-BP1; FGF-binding protein 1; FGFBP-1; 17 kDa HBGF-binding protein; HBp17 [Similar Products]
UniProt Entry Name
FGFP1_HUMAN
NCBI Summary for FGFBP1
This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]
UniProt Comments for FGFBP1
FGFBP1: Acts as a carrier protein that release fibroblast- binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. Belongs to the fibroblast growth factor-binding protein family.
Chromosomal Location of Human Ortholog: 4p15.32
Cellular Component: extracellular space; cell surface; plasma membrane
Molecular Function: heparin binding; protein binding; fibroblast growth factor binding
Biological Process: negative regulation of cell proliferation; cell-cell signaling; positive regulation of cell proliferation; positive regulation of fibroblast growth factor receptor signaling pathway; signal transduction
Research Articles on FGFBP1
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Products associated with FGFBP1 elisa kit
Diseases associated with FGFBP1 elisa kit
Organs/Tissues associated with FGFBP1 elisa kit
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