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FLNC elisa kit :: Rat Filamin C, Gamma ELISA Kit

Scan QR to view Datasheet Catalog #    MBS019762 FLNC elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Filamin C, Gamma (FLNC), ELISA Kit

 Also Known As   

Rat Filamin C, Gamma ELISA Kit

 Product Gene Name   

FLNC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    607747
 3D Structure    ModBase 3D Structure for Q8WUP2
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 Species Reactivity    Rat
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FLNC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FLNC purchase    MBS019762 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Filamin C, Gamma (FLNC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FLNC. The ELISA analytical biochemical technique of the MBS019762 kit is based on FLNC antibody-FLNC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FLNC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FLNC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FLNC. It may not necessarily be applicable to this product.
 NCBI GI #    66932988
 NCBI GeneID    54751
 NCBI Accession #    NP_001019387.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001024216.1 [Other Products]
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 UniProt Primary Accession #    Q8WUP2 [Other Products]
 UniProt Secondary Accession #    Q5VVE0; Q5VVE1; Q8IX23; Q96T00; Q9UFD6; B3KNY0 [Other Products]
 UniProt Related Accession #    Q8WUP2 [Other Products]
 Molecular Weight    40,670 Da
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 NCBI Official Full Name    filamin-binding LIM protein 1 isoform c
 NCBI Official Synonym Full Names    filamin binding LIM protein 1
 NCBI Official Symbol    FBLIM1 [Similar Products]
 NCBI Official Synonym Symbols   
CAL; FBLP1; FBLP-1
[Similar Products]
 NCBI Protein Information    filamin-binding LIM protein 1; migfilin; CSX-associated LIM; MIG2-interacting protein; filamin-binding LIM protein-1; mitogen-inducible 2 interacting protein; mitogen-inducible 2-interacting protein
 UniProt Protein Name    Filamin-binding LIM protein 1
 UniProt Synonym Protein Names   
Migfilin; Mitogen-inducible 2-interacting protein
 Protein Family    Filamin
 UniProt Gene Name    FBLIM1 [Similar Products]
 UniProt Synonym Gene Names    FBLP1; FBLP-1 [Similar Products]
 UniProt Entry Name    FBLI1_HUMAN
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 NCBI Summary for FLNC    This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FLNC    FBLIM1: Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin- containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1p36.21

Cellular Component: focal adhesion; stress fiber; cell cortex; cytosol

Molecular Function: zinc ion binding; filamin binding

Biological Process: regulation of cell shape; cell-cell adhesion; regulation of integrin activation
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 Research Articles on FLNC    1. the present study emphasizes for the first time to our knowledge the role of Migfilin in osteoarthritis(OA) and highlights the importance of cell-ECM adhesion proteins in OA pathogenesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FLNC elisa kitPathways associated with FLNC elisa kit
 Reference Product  PubMed Publications
 FLNC elisa kit  >9 publications with FLNC and FLNC
 FLNA elisa kit  >3 publications with FLNC and FLNA
 VASP elisa kit  >2 publications with FLNC and VASP
 Products by Pathway  Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-extracellular Matrix Interactions Pathway antibodies  Cell-extracellular Matrix Interactions Pathway Diagram
Diseases associated with FLNC elisa kitOrgans/Tissues associated with FLNC elisa kit
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with FLNC and Breast Neoplasms
 Lung Neoplasms Antibodies  >1 publications with FLNC and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >3 publications with FLNC and Muscle
 Bone Antibodies  >2 publications with FLNC and Bone
 Skin Antibodies  >2 publications with FLNC and Skin
 Vascular Antibodies  >2 publications with FLNC and Vascular
 Embryonic Tissue Antibodies  >2 publications with FLNC and Embryonic Tissue
 Connective Tissue Antibodies  >1 publications with FLNC and Connective Tissue
 Bone Marrow Antibodies  >1 publications with FLNC and Bone Marrow
 Lung Antibodies  >1 publications with FLNC and Lung
 Mouth Antibodies  >1 publications with FLNC and Mouth
 Brain Antibodies  >1 publications with FLNC and Brain
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