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FOXC2 elisa kit :: Rat Forkhead Box Protein C2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS012629 FOXC2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Forkhead Box Protein C2 (FOXC2), ELISA Kit

 Also Known As   

Rat Forkhead Box Protein C2 ELISA Kit

 Product Gene Name   

FOXC2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 16; NC_000016.9 (86600857..86602539). Location: 16q24.1
 OMIM    153200
 3D Structure    ModBase 3D Structure for Q99958
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 Species Reactivity    Rat
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FOXC2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FOXC2 purchase    MBS012629 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Forkhead Box Protein C2 (FOXC2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FOXC2. The ELISA analytical biochemical technique of the MBS012629 kit is based on FOXC2 antibody-FOXC2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FOXC2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FOXC2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FOXC2. It may not necessarily be applicable to this product.
 NCBI GI #    4885237
 NCBI GeneID    2303
 NCBI Accession #    NP_005242.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005251.2 [Other Products]
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 UniProt Primary Accession #    Q99958 [Other Products]
 UniProt Secondary Accession #    Q14DA6; C6KMR9 [Other Products]
 UniProt Related Accession #    Q99958 [Other Products]
 Molecular Weight    53,719 Da
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 NCBI Official Full Name    forkhead box protein C2
 NCBI Official Synonym Full Names    forkhead box C2 (MFH-1, mesenchyme forkhead 1)
 NCBI Official Symbol    FOXC2 [Similar Products]
 NCBI Official Synonym Symbols   
LD; MFH1; MFH-1; FKHL14
[Similar Products]
 NCBI Protein Information    forkhead box protein C2; MFH-1,mesenchyme forkhead 1; transcription factor FKH-14; mesenchyme fork head protein 1; forkhead-related protein FKHL14; forkhead, Drosophila, homolog-like 14
 UniProt Protein Name    Forkhead box protein C2
 UniProt Synonym Protein Names   
Forkhead-related protein FKHL14; Mesenchyme fork head protein 1; MFH-1 protein; Transcription factor FKH-14
 Protein Family    Forkhead box protein
 UniProt Gene Name    FOXC2 [Similar Products]
 UniProt Synonym Gene Names    FKHL14; MFH1; MFH-1 protein [Similar Products]
 UniProt Entry Name    FOXC2_HUMAN
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 NCBI Summary for FOXC2    This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FOXC2    FOXC2: Transcriptional activator. Might be involved in the formation of special mesenchymal tissues. Defects in FOXC2 are the cause of lymphedema hereditary type 2 (LMPH2); also known as Meige lymphedema. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections, and physical impairment. Defects in FOXC2 are a cause of lymphedema-yellow nails (LYYN). LYYN is characterized by yellow, dystrophic, thick and slowly growing nails, associated with lymphedema and respiratory involvement. Lymphedema occurs more often in the lower limbs. It can appear at birth or later in life. Onset generally follows the onset of ungual abnormalities. Defects in FOXC2 are a cause of lymphedema-distichiasis (LYD). LYD is characterized by primary limb lymphedema usually starting at puberty (but in some cases later or at birth) and associated with distichiasis (double rows of eyelashes, with extra eyelashes growing from the Meibomian gland orifices).

Protein type: DNA-binding; Apoptosis; Cell development/differentiation; Transcription factor

Chromosomal Location of Human Ortholog: 16q24.1

Cellular Component: nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; chromatin DNA binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; collagen fibril organization; neural crest cell development; heart development; positive regulation of transcription, DNA-dependent; response to hormone stimulus; cardiac muscle cell proliferation; negative regulation of transcription from RNA polymerase II promoter; ureteric bud development; lymphangiogenesis; ventricular cardiac muscle morphogenesis; mesoderm development; regulation of blood vessel size; ossification; somitogenesis; Notch signaling pathway; camera-type eye development; positive regulation of cell adhesion mediated by integrin; regulation of organ growth; embryonic viscerocranium morphogenesis; regulation of transcription from RNA polymerase II promoter; patterning of blood vessels; paraxial mesodermal cell fate commitment; insulin receptor signaling pathway; embryonic heart tube development; artery morphogenesis; blood vessel remodeling; positive regulation of transcription from RNA polymerase II promoter; vascular endothelial growth factor receptor signaling pathway; metanephros development

Disease: Lymphedema-distichiasis Syndrome
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 Research Articles on FOXC2    1. de novo mutations and rare variants in hypoplastic left heart syndrome for FOXC2 gene
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FOXC2 elisa kitPathways associated with FOXC2 elisa kit
 Reference Product  PubMed Publications
 SHH elisa kit  >11 publications with FOXC2 and SHH
 DLL4 elisa kit  >7 publications with FOXC2 and DLL4
 ANGPT2 elisa kit  >5 publications with FOXC2 and ANGPT2
 CXCR4 elisa kit  >4 publications with FOXC2 and CXCR4
 VEGFA elisa kit  >4 publications with FOXC2 and VEGFA
 MESP1 elisa kit  >1 publications with FOXC2 and MESP1
 NRP1 elisa kit  >1 publications with FOXC2 and NRP1
 MYOD1 elisa kit  >1 publications with FOXC2 and MYOD1
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Heart Development Pathway antibodies  Heart Development Pathway Diagram
Diseases associated with FOXC2 elisa kit
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >36 publications with FOXC2 and Congenital Abnormalities
 Lymphedema distichiasis syndrome Antibodies  >29 publications with FOXC2 and Lymphedema distichiasis syndrome
 Neoplasms Antibodies  >28 publications with FOXC2 and Neoplasms
 Cardiovascular Abnormalities Antibodies  >14 publications with FOXC2 and Cardiovascular Abnormalities
 Breast Neoplasms Antibodies  >13 publications with FOXC2 and Breast Neoplasms
 Abnormalities, Multiple Antibodies  >12 publications with FOXC2 and Abnormalities, Multiple
 Edema Antibodies  >11 publications with FOXC2 and Edema
 Disease Models, Animal Antibodies  >11 publications with FOXC2 and Disease Models, Animal
 Eye Abnormalities Antibodies  >10 publications with FOXC2 and Eye Abnormalities
 Musculoskeletal Abnormalities Antibodies  >8 publications with FOXC2 and Musculoskeletal Abnormalities
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