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GSTA1 elisa kit :: Rat GSTA1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2500730
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GSTA1, ELISA Kit

★Popular Item★
 Also Known As   

Rat GSTA1 (Glutathione S Transferase Alpha 1) ELISA Kit

 Product Gene Name   

GSTA1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    138359
 3D Structure    ModBase 3D Structure for P08263
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Rat GSTA1. No significant cross-reactivity or interference between Rat GSTA1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat GSTA1 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.313--20ng/mL
 Sensitivity    0.188ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GSTA1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GSTA1 purchase    MBS2500730 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the GSTA1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313--20ng/mL in biological research samples containing GSTA1, with an estimated sensitivity of 0.188ng/mL. The ELISA analytical biochemical technique of the MBS2500730 kit is based on GSTA1 antibody-GSTA1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GSTA1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GSTA1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for GSTA1 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of GSTA1 in Rat serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat GSTA1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat GSTA1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat GSTA1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat GSTA1. You can calculate the concentration of Rat GSTA1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of GSTA1 elisa kit    GSTA1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2500730. Click to request current manual
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NCBI/Uniprot data below describe general gene information for GSTA1. It may not necessarily be applicable to this product.
 NCBI GI #    22091454
 NCBI GeneID    2938
 NCBI Accession #    NP_665683.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_145740.3 [Other Products]
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 UniProt Primary Accession #    P08263 [Other Products]
 UniProt Secondary Accession #    Q14750; Q5GHF8; Q5SZC1 [Other Products]
 UniProt Related Accession #    P08263 [Other Products]
 Molecular Weight    25,631 Da
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 NCBI Official Full Name    glutathione S-transferase A1
 NCBI Official Synonym Full Names    glutathione S-transferase alpha 1
 NCBI Official Symbol    GSTA1 [Similar Products]
 NCBI Official Synonym Symbols   
GST2; GTH1; GSTA1-1
[Similar Products]
 NCBI Protein Information    glutathione S-transferase A1; GST HA subunit 1; GST class-alpha member 1; GST, class alpha, 1; GST-epsilon; S-(hydroxyalkyl)glutathione lyase A1; glutathione S-alkyltransferase A1; glutathione S-aryltransferase A1; glutathione S-transferase 2; glutathione S-transferase Ha subunit 1
 UniProt Protein Name    Glutathione S-transferase A1
 UniProt Synonym Protein Names   
GST HA subunit 1; GST class-alpha member 1; GST-epsilon; GSTA1-1; GTH1Glutathione S-transferase A1, N-terminally processed
 Protein Family    Glutathione S-transferase
 UniProt Gene Name    GSTA1 [Similar Products]
 UniProt Entry Name    GSTA1_HUMAN
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 NCBI Summary for GSTA1    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GSTA1    GSTA1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Alpha family.

Protein type: EC 2.5.1.18; Transferase; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Other Amino Acids Metabolism - glutathione

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: cytosol

Molecular Function: glutathione transferase activity

Biological Process: glutathione metabolic process; epithelial cell differentiation; metabolic process; xenobiotic metabolic process
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 Research Articles on GSTA1    1. The role of the glutathione S-transferase A1, M1, P1 and T1 gene polymorphisms and potential effect modification by occupational exposure to different chemicals in Serbian bladder cancer male patients, was investigated.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GSTA1 elisa kitPathways associated with GSTA1 elisa kit
 Reference Product  PubMed Publications
 GSTA2 elisa kit  >49 publications with GSTA1 and GSTA2
 CYP3A4 elisa kit  >17 publications with GSTA1 and CYP3A4
 CYP2B6 elisa kit  >16 publications with GSTA1 and CYP2B6
 CYP1B1 elisa kit  >12 publications with GSTA1 and CYP1B1
 GPX1 elisa kit  >5 publications with GSTA1 and GPX1
 GSR elisa kit  >3 publications with GSTA1 and GSR
 Products by Pathway  Pathway Diagram
 4-hydroxy-2-nonenal Detoxification Pathway antibodies  4-hydroxy-2-nonenal Detoxification Pathway Diagram
 4-hydroxy-2-nonenal Detoxification Pathway antibodies  4-hydroxy-2-nonenal Detoxification Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway antibodies  Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway Diagram
 Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway antibodies  Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway Diagram
 Defective GGT1 Causes Glutathionuria (GLUTH) Pathway antibodies  Defective GGT1 Causes Glutathionuria (GLUTH) Pathway Diagram
 Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway antibodies  Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway Diagram
Diseases associated with GSTA1 elisa kitOrgans/Tissues associated with GSTA1 elisa kit
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >33 publications with GSTA1 and Liver Diseases
 Breast Neoplasms Antibodies  >24 publications with GSTA1 and Breast Neoplasms
 Inflammation Antibodies  >21 publications with GSTA1 and Inflammation
 Liver Neoplasms Antibodies  >18 publications with GSTA1 and Liver Neoplasms
 Cardiovascular Diseases Antibodies  >12 publications with GSTA1 and Cardiovascular Diseases
 Urinary Bladder Neoplasms Antibodies  >11 publications with GSTA1 and Urinary Bladder Neoplasms
 Necrosis Antibodies  >9 publications with GSTA1 and Necrosis
 Carcinoma, Hepatocellular Antibodies  >9 publications with GSTA1 and Carcinoma, Hepatocellular
 Lung Neoplasms Antibodies  >9 publications with GSTA1 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >8 publications with GSTA1 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >118 publications with GSTA1 and Liver
 Lung Antibodies  >32 publications with GSTA1 and Lung
 Kidney Antibodies  >26 publications with GSTA1 and Kidney
 Intestine Antibodies  >22 publications with GSTA1 and Intestine
 Heart Antibodies  >16 publications with GSTA1 and Heart
 Bladder Antibodies  >11 publications with GSTA1 and Bladder
 Prostate Antibodies  >9 publications with GSTA1 and Prostate
 Ovary Antibodies  >7 publications with GSTA1 and Ovary
 Brain Antibodies  >6 publications with GSTA1 and Brain
 Embryonic Tissue Antibodies  >5 publications with GSTA1 and Embryonic Tissue
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