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GFAP elisa kit :: Rat Glial Fibrillary Acidic Protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS042687 GFAP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glial Fibrillary Acidic Protein (GFAP), ELISA Kit

 Also Known As   

Rat Glial Fibrillary Acidic Protein ELISA Kit

 Product Gene Name   

GFAP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 Chromosome Location    Chromosome: 17; NC_000017.10 (42982994..42992920, complement). Location: 17q21
 OMIM    137780
 3D Structure    ModBase 3D Structure for P14136
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 Species Reactivity    Rat
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Serum, Plasma and Tissue Homogenate
 Detection Range    0.625pg/ml-20pg/ml.
 Sensitivity    0.1pg/ml.
 Assay Type    Sandwich
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of GFAP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GFAP purchase    MBS042687 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glial Fibrillary Acidic Protein (GFAP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625pg/ml-20pg/ml in biological research samples containing GFAP, with an estimated sensitivity of 0.1pg/ml. The ELISA analytical biochemical technique of the MBS042687 kit is based on GFAP antibody-GFAP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GFAP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GFAP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma and Tissue Homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for GFAP elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GFAP (hereafter termed this analyte) in undiluted original Rat serum, plasma and tissue homogenate samples.
Sample Manual Insert of MBS042687
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NCBI/Uniprot data below describe general gene information for GFAP. It may not necessarily be applicable to this product.
 NCBI GI #    334688844
 NCBI GeneID    2670
 NCBI Accession #    NP_001229305.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001242376.1 [Other Products]
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 UniProt Primary Accession #    P14136 [Other Products]
 UniProt Secondary Accession #    Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0; B2RD44; D3DX59; E9PAX3 [Other Products]
 UniProt Related Accession #    P14136 [Other Products]
 Molecular Weight    49,880 Da
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 NCBI Official Full Name    glial fibrillary acidic protein isoform 3
 NCBI Official Synonym Full Names    glial fibrillary acidic protein
 NCBI Official Symbol    GFAP [Similar Products]
 NCBI Protein Information    glial fibrillary acidic protein
 UniProt Protein Name    Glial fibrillary acidic protein
 Protein Family    Glial fibrillary acidic protein
 UniProt Gene Name    GFAP [Similar Products]
 UniProt Synonym Gene Names    GFAP [Similar Products]
 UniProt Entry Name    GFAP_HUMAN
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 NCBI Summary for GFAP    This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
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 UniProt Comments for GFAP    GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: membrane; cytoplasm; intermediate filament; cytosol

Molecular Function: integrin binding; structural constituent of cytoskeleton; kinase binding

Biological Process: extracellular matrix organization and biogenesis; Bergmann glial cell differentiation; regulation of neurotransmitter uptake; response to wounding; intermediate filament organization; neurite regeneration; astrocyte development

Disease: Alexander Disease
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 Research Articles on GFAP    1. The protein and mRNA expressions of GFAP decreased significantly in grade III and IV astrocytoma compared with those in grade II astrocytoma and normal brain tissues.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with GFAP elisa kitDiseases associated with GFAP elisa kit
 Products by Pathway  Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
 Nuclear Signaling By ERBB4 Pathway antibodies  Nuclear Signaling By ERBB4 Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By ERBB4 Pathway antibodies  Signaling By ERBB4 Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >4376 publications with GFAP and Nervous System Diseases
 Brain Diseases Antibodies  >3323 publications with GFAP and Brain Diseases
 Gliosis Antibodies  >1004 publications with GFAP and Gliosis
 Cardiovascular Diseases Antibodies  >767 publications with GFAP and Cardiovascular Diseases
 Brain Injuries Antibodies  >609 publications with GFAP and Brain Injuries
 Drug Toxicity Antibodies  >539 publications with GFAP and Drug Toxicity
 Nerve Degeneration Antibodies  >508 publications with GFAP and Nerve Degeneration
 Inflammation Antibodies  >493 publications with GFAP and Inflammation
 Necrosis Antibodies  >492 publications with GFAP and Necrosis
 Epilepsy Antibodies  >325 publications with GFAP and Epilepsy
Organs/Tissues associated with GFAP elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7124 publications with GFAP and Brain
 Nerve Antibodies  >3103 publications with GFAP and Nerve
 Blood Antibodies  >1394 publications with GFAP and Blood
 Spinal Cord Antibodies  >1214 publications with GFAP and Spinal Cord
 Eye Antibodies  >908 publications with GFAP and Eye
 Muscle Antibodies  >466 publications with GFAP and Muscle
 Ganglia Antibodies  >258 publications with GFAP and Ganglia
 Bone Marrow Antibodies  >226 publications with GFAP and Bone Marrow
 Liver Antibodies  >184 publications with GFAP and Liver
 Connective Tissue Antibodies  >161 publications with GFAP and Connective Tissue
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