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GDF11 elisa kit :: Rat Growth Differentiation Factor 11 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS041865
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $500 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,250 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,395 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Growth Differentiation Factor 11 (GDF11), ELISA Kit

 Also Known As   

Rat Growth Differentiation Factor 11 ELISA Kit

 Product Gene Name   

GDF11 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 12; NC_000012.11 (56137064..56146665). Location: 12q13.2
 OMIM    603936
 3D Structure    ModBase 3D Structure for O95390
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 Species Reactivity    Rat
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 Specificity    No significant cross-reactivity or interference between Rat GDF11 and analogues was observed.
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 Samples    Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids
 Assay Type    Sandwich
 Detection Range    62.5 pg/ml 2000 pg/ml.
 Sensitivity    10 pg/ml.
 Intended Uses    ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate GDF11 concentrations in Rat serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GDF11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GDF11 purchase    MBS041865 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Growth Differentiation Factor 11 (GDF11) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5 pg/ml 2000 pg/ml in biological research samples containing GDF11, with an estimated sensitivity of 10 pg/ml. The ELISA analytical biochemical technique of the MBS041865 kit is based on GDF11 antibody-GDF11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GDF11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GDF11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for GDF11 elisa kit

   Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate GDF11 concentrations in Rat serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!
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 Typical Testing Data/Standard Curve (for reference only) of GDF11 elisa kit    GDF11 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS041865. Click to request current manual
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NCBI/Uniprot data below describe general gene information for GDF11. It may not necessarily be applicable to this product.
 NCBI GI #    5031613
 NCBI GeneID    10220
 NCBI Accession #    NP_005802.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005811.3 [Other Products]
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 UniProt Primary Accession #    O95390 [Other Products]
 UniProt Secondary Accession #    Q9UID1; Q9UID2 [Other Products]
 UniProt Related Accession #    O95390 [Other Products]
 Molecular Weight    45,091 Da
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 NCBI Official Full Name    growth/differentiation factor 11
 NCBI Official Synonym Full Names    growth differentiation factor 11
 NCBI Official Symbol    GDF11 [Similar Products]
 NCBI Official Synonym Symbols   
BMP11; BMP-11
[Similar Products]
 NCBI Protein Information    growth/differentiation factor 11; GDF-11; bone morphogenetic protein 11
 UniProt Protein Name    Growth/differentiation factor 11
 UniProt Synonym Protein Names   
Bone morphogenetic protein 11
 Protein Family    Growth/differentiation factor
 UniProt Gene Name    GDF11 [Similar Products]
 UniProt Synonym Gene Names    BMP11; GDF-11; BMP-11 [Similar Products]
 UniProt Entry Name    GDF11_HUMAN
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 NCBI Summary for GDF11    The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GDF11    GDF11: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: nervous system development; cell maturation; palate development; regulation of apoptosis; negative regulation of cell proliferation; negative regulation of cell differentiation; camera-type eye morphogenesis; spinal cord anterior/posterior patterning; ureteric bud development; regulation of MAPKKK cascade; pancreas development; mesoderm development; cell development; metanephros development; skeletal development; growth
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 Research Articles on GDF11    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GDF11 elisa kitDiseases associated with GDF11 elisa kit
 Reference Product  PubMed Publications
 PCSK5 elisa kit  >3 publications with GDF11 and PCSK5
 WFIKKN1 elisa kit  >3 publications with GDF11 and WFIKKN1
 ACVR2B elisa kit  >3 publications with GDF11 and ACVR2B
 WIF1 elisa kit  >1 publications with GDF11 and WIF1
 CDKN1A elisa kit  >1 publications with GDF11 and CDKN1A
 MAFA elisa kit  >1 publications with GDF11 and MAFA
 FOXG1 elisa kit  >1 publications with GDF11 and FOXG1
 ACVR1B elisa kit  >1 publications with GDF11 and ACVR1B
 ATOH7 elisa kit  >1 publications with GDF11 and ATOH7
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >7 publications with GDF11 and Congenital Abnormalities
 Kidney Diseases Antibodies  >3 publications with GDF11 and Kidney Diseases
 Disease Models, Animal Antibodies  >2 publications with GDF11 and Disease Models, Animal
 Insulin Resistance Antibodies  >1 publications with GDF11 and Insulin Resistance
 Neoplasm Metastasis Antibodies  >1 publications with GDF11 and Neoplasm Metastasis
 Fatty Liver Antibodies  >1 publications with GDF11 and Fatty Liver
 Urogenital Abnormalities Antibodies  >1 publications with GDF11 and Urogenital Abnormalities
 Necrosis Antibodies  >1 publications with GDF11 and Necrosis
Organs/Tissues associated with GDF11 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >60 publications with GDF11 and Bone
 Muscle Antibodies  >20 publications with GDF11 and Muscle
 Embryonic Tissue Antibodies  >16 publications with GDF11 and Embryonic Tissue
 Nerve Antibodies  >11 publications with GDF11 and Nerve
 Kidney Antibodies  >8 publications with GDF11 and Kidney
 Heart Antibodies  >6 publications with GDF11 and Heart
 Eye Antibodies  >6 publications with GDF11 and Eye
 Blood Antibodies  >5 publications with GDF11 and Blood
 Mouth Antibodies  >5 publications with GDF11 and Mouth
 Pancreas Antibodies  >5 publications with GDF11 and Pancreas
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