NP_620636.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
99,919 Da
NCBI Official Full Name
helicase-like transcription factor
NCBI Official Synonym Full Names
helicase-like transcription factor
NCBI Official Synonym Symbols
ZBU1; HLTF1; RNF80; HIP116; SNF2L3; HIP116A; SMARCA3 [Similar Products]
NCBI Protein Information
helicase-like transcription factor; DNA-binding protein/plasminogen activator inhibitor 1 regulator; DNA-binding protein/plasminogen activator inhibitor-1 regulator; RING finger protein 80; SNF2-like 3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3; sucrose nonfermenting protein 2-like 3; sucrose nonfermenting-like 3
UniProt Protein Name
Helicase-like transcription factor
UniProt Synonym Protein Names
DNA-binding protein/plasminogen activator inhibitor 1 regulator; HIP116; RING finger protein 80; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3; Sucrose nonfermenting protein 2-like 3
UniProt Synonym Gene Names
UniProt Entry Name
HLTF_HUMAN
NCBI Summary for HLTF
This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008]
UniProt Comments for HLTF
SMARCA3: an enzyme with apparent ATP-dependent DNA helicase activity. Belongs to the SNF2/RAD54 helicase family, RAD16 subfamily. Two alternatively spliced human isoforms have been described.
Protein type: EC 3.6.1.-; EC 3.6.4.-; DNA-binding; Helicase; Ubiquitin ligase; Ligase; EC 6.3.2.-; EC 6.3.2.19; Ubiquitin conjugating system; Nucleolus
Chromosomal Location of Human Ortholog: 3q25.1-q26.1
Cellular Component: nucleoplasm; membrane; cytoplasm; nucleolus; nucleus
Molecular Function: protein binding; DNA binding; zinc ion binding; ATPase activity; helicase activity; ATP binding; ligase activity
Biological Process: regulation of transcription from RNA polymerase II promoter; protein polyubiquitination; transcription, DNA-dependent; regulation of transcription, DNA-dependent; postreplication repair; chromatin modification
Research Articles on HLTF
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Products associated with HLTF elisa kit
Pathways associated with HLTF elisa kit
Diseases associated with HLTF elisa kit
Organs/Tissues associated with HLTF elisa kit
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