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Hpt/HP elisa kit :: Rat Haptoglobin, Hpt/HP ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9304282 Hpt/HP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Haptoglobin, Hpt/HP, ELISA Kit

 Also Known As   

Rat Haptoglobin, Hpt/HP ELISA Kit

 Product Gene Name   

Hpt/HP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 16; NC_000016.9 (72088508..72094955). Location: 16q22.2
 OMIM    140100
 3D Structure    ModBase 3D Structure for P00738
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 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Hpt/HP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Hpt/HP purchase    MBS9304282 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Haptoglobin, Hpt/HP, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Hpt/HP. The ELISA analytical biochemical technique of the MBS9304282 kit is based on Hpt/HP antibody-Hpt/HP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Hpt/HP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Hpt/HP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Hpt/HP. It may not necessarily be applicable to this product.
 NCBI GI #    186910296
 NCBI GeneID    3240
 NCBI Accession #    NP_001119574.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001126102.1 [Other Products]
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 UniProt Primary Accession #    P00738 [Other Products]
 UniProt Secondary Accession #    P00737; Q0VAC4; Q2PP15; Q3B7J0; Q6LBY9; Q9UC67; B0AZL5 [Other Products]
 UniProt Related Accession #    P00738 [Other Products]
 Molecular Weight    45,205 Da
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 NCBI Official Full Name    haptoglobin isoform 2 preproprotein
 NCBI Official Synonym Full Names    haptoglobin
 NCBI Official Symbol    HP [Similar Products]
 NCBI Official Synonym Symbols   
BP; HPA1S; HP2ALPHA2
[Similar Products]
 NCBI Protein Information    haptoglobin; zonulin; binding peptide; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; haptoglobin, beta polypeptide; haptoglobin, alpha polypeptide
 UniProt Protein Name    Haptoglobin
 UniProt Synonym Protein Names   
Zonulin
 UniProt Gene Name    HP [Similar Products]
 UniProt Entry Name    HPT_HUMAN
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 NCBI Summary for Hpt/HP    This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for Hpt/HP    HP: Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes. Defects in HP are the cause of anhaptoglobinemia (AHP). AHP is a condition characterized by the absence of the serum glycoprotein haptoglobin. Serum levels of haptoglobin vary among normal persons: levels are low in the neonatal period and in the elderly, differ by population, and can be influenced by environmental factors, such as infection. Secondary hypohaptoglobinemia can occur as a consequence of hemolysis, during which haptoglobin binds to free hemoglobin. Belongs to the peptidase S1 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q22.2

Cellular Component: extracellular space; extracellular region

Molecular Function: antioxidant activity; protein binding; hemoglobin binding; catalytic activity

Biological Process: receptor-mediated endocytosis; response to hydrogen peroxide; metabolic process; immune system process; negative regulation of oxidoreductase activity; defense response to bacterium; acute-phase response; defense response

Disease: Anhaptoglobinemia
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 Research Articles on Hpt/HP    1. specific changes in glycan structures of Hpt, such as enhanced glycan branching and fucose content, are associated with psoriasis, and that differences between circulating and skin Hpt do exist.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Hpt/HP elisa kitPathways associated with Hpt/HP elisa kit
 Reference Product  PubMed Publications
 CD163 elisa kit  >54 publications with Hpt/HP and CD163
 ALB elisa kit  >38 publications with Hpt/HP and ALB
 IL6 elisa kit  >22 publications with Hpt/HP and IL6
 APOE elisa kit  >22 publications with Hpt/HP and APOE
 APOA1 elisa kit  >9 publications with Hpt/HP and APOA1
 HBB elisa kit  >4 publications with Hpt/HP and HBB
 MIS12 elisa kit  >2 publications with Hpt/HP and MIS12
 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
 Amb2 Integrin Signaling Pathway antibodies  Amb2 Integrin Signaling Pathway Diagram
Diseases associated with Hpt/HP elisa kitOrgans/Tissues associated with Hpt/HP elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1366 publications with Hpt/HP and Cardiovascular Diseases
 Inflammation Antibodies  >921 publications with Hpt/HP and Inflammation
 Heart Diseases Antibodies  >610 publications with Hpt/HP and Heart Diseases
 Hypersensitivity Antibodies  >584 publications with Hpt/HP and Hypersensitivity
 Liver Diseases Antibodies  >488 publications with Hpt/HP and Liver Diseases
 Kidney Diseases Antibodies  >411 publications with Hpt/HP and Kidney Diseases
 Drug Toxicity Antibodies  >390 publications with Hpt/HP and Drug Toxicity
 Necrosis Antibodies  >385 publications with Hpt/HP and Necrosis
 Hypertension Antibodies  >374 publications with Hpt/HP and Hypertension
 Autoimmune Diseases Antibodies  >368 publications with Hpt/HP and Autoimmune Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4880 publications with Hpt/HP and Blood
 Stomach Antibodies  >1220 publications with Hpt/HP and Stomach
 Liver Antibodies  >1039 publications with Hpt/HP and Liver
 Lung Antibodies  >935 publications with Hpt/HP and Lung
 Muscle Antibodies  >628 publications with Hpt/HP and Muscle
 Ovary Antibodies  >129 publications with Hpt/HP and Ovary
 Testis Antibodies  >47 publications with Hpt/HP and Testis
 Uncharacterized Tissue Antibodies  >1 publications with Hpt/HP and Uncharacterized Tissue
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