Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow IL-21 rightarrow Rat IL-21  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Estrogen ELISA Kit
 • Pulmonary surfactant-associated protein B (SFTPB) ELISA Kit
 • TUSC3-N33 (TUSC3 ) Antibody
 • Mitogen Activated Protein Kinase Kinase 2 (MAP2K2) Antibody
 • Heparanase (HPSE) ELISA Kit
 • Histidine-tRNA ligase (HARS) Antibody
 • Annexin A10 (ANXA10) Antibody
 • ADAM metallopeptidase with thrombospondin type 1 motif, 16 (... ELISA Kit
 • Myosin-11 (MYH11) ELISA Kit
 • Epo-R (EPOR) Antibody
 • Fxn Antibody
 • CIB1 Antibody
 • TSHR ELISA Kit
 • HEPATITIS B SURFACE ANTIGEN AD-AY Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

IL-21 elisa kit :: Rat IL-21 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2504873
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL-21, ELISA Kit

★Popular Item★
 Also Known As   

Rat IL-21 (Interleukin 21) ELISA Kit

 Product Gene Name   

IL-21 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2504873 COA    COA PDF
 OMIM    605384
 3D Structure    ModBase 3D Structure for Q9HBE4
Section Bar
 Species Reactivity    Rat
Section Bar
 Specificity    This kit recognizes natural and recombinant Rat IL-21. No significant cross-reactivity or interference between Rat IL-21 and analogues was observed.
Section Bar
 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    15.625-1000pg/mL
 Sensitivity    Min: 9.375pg/mL; Max: 1000pg/mL
Section Bar
 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL-21 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL-21 purchase    MBS2504873 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the IL-21, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.625-1000pg/mL in biological research samples containing IL-21, with an estimated sensitivity of Min: 9.375pg/mL; Max: 1000pg/mL. The ELISA analytical biochemical technique of the MBS2504873 kit is based on IL-21 antibody-IL-21 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL-21 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL-21. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Related Product Information for IL-21 elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rat IL-21 concentrations in serum, plasma and other biological fluids.

Principle of the Assay||This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to IL-21. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for IL-21 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain IL-21, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of IL-21. You can calculate the concentration of IL-21 in the samples by comparing the OD of the samples to the standard curve.
Section Bar
 Typical Testing Data/Standard Curve (for reference only) of IL-21 elisa kit    IL-21 elisa kit Typical Testing Data/Standard Curve (for reference only) image
Table BarTOPTable Bar
Sample Manual Insert of MBS2504873. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for IL-21. It may not necessarily be applicable to this product.
 NCBI GI #    333033767
 NCBI GeneID    59067
 NCBI Accession #    NP_001193935.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001207006.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q9HBE4 [Other Products]
 UniProt Secondary Accession #    A5J0L4 [Other Products]
 UniProt Related Accession #    Q9HBE4 [Other Products]
 Molecular Weight    16,867 Da
Table BarTOPTable Bar
 NCBI Official Full Name    interleukin-21 isoform 2
 NCBI Official Synonym Full Names    interleukin 21
 NCBI Official Symbol    IL21 [Similar Products]
 NCBI Official Synonym Symbols   
Za11; IL-21; CVID11
[Similar Products]
 NCBI Protein Information    interleukin-21; interleukin-21 isoform
 UniProt Protein Name    Interleukin-21
 UniProt Synonym Protein Names   
Za11
 UniProt Gene Name    IL21 [Similar Products]
 UniProt Synonym Gene Names    IL-21 [Similar Products]
 UniProt Entry Name    IL21_HUMAN
Section Bar
 NCBI Summary for IL-21    This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Section Bar
 UniProt Comments for IL-21    IL21: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. Belongs to the IL-15/IL-21 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Apoptosis; Secreted, signal peptide; Cell development/differentiation; Cytokine

Chromosomal Location of Human Ortholog: 4q26-q27

Cellular Component: extracellular space

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interleukin-2 receptor binding; cytokine activity

Biological Process: positive regulation of interleukin-17 production; positive regulation of natural killer cell cytokine production; cell maturation; signal transduction; positive regulation of natural killer cell mediated cytotoxicity; positive regulation of interleukin-10 production; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of natural killer cell differentiation; positive regulation of tissue remodeling; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of cell proliferation; positive regulation of B cell proliferation; immune response; positive regulation of T cell proliferation; positive regulation of interferon-gamma biosynthetic process; positive regulation of inflammatory response

Disease: Immunodeficiency, Common Variable, 11
Table BarTOPTable Bar
 Research Articles on IL-21    1. IL-21 signals through the STAT-3 and STAT- 5b signaling pathway in the CIK cell pool.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with IL-21 elisa kitPathways associated with IL-21 elisa kit
 Reference Product  PubMed Publications
 IL21R elisa kit  >372 publications with IL-21 and IL21R
 STAT3 elisa kit  >118 publications with IL-21 and STAT3
 IL15 elisa kit  >83 publications with IL-21 and IL15
 IL4 elisa kit  >14 publications with IL-21 and IL4
 IL13 elisa kit  >6 publications with IL-21 and IL13
 IL9 elisa kit  >5 publications with IL-21 and IL9
 IL7 elisa kit  >4 publications with IL-21 and IL7
 NFATC2 elisa kit  >1 publications with IL-21 and NFATC2
 TSLP elisa kit  >1 publications with IL-21 and TSLP
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with IL-21 elisa kitOrgans/Tissues associated with IL-21 elisa kit
 Disease Name  Pubmed Publications
 Autoimmune Diseases Antibodies  >270 publications with IL-21 and Autoimmune Diseases
 Inflammation Antibodies  >175 publications with IL-21 and Inflammation
 Disease Models, Animal Antibodies  >119 publications with IL-21 and Disease Models, Animal
 Lupus Erythematosus, Systemic Antibodies  >73 publications with IL-21 and Lupus Erythematosus, Systemic
 Necrosis Antibodies  >64 publications with IL-21 and Necrosis
 Liver Diseases Antibodies  >45 publications with IL-21 and Liver Diseases
 Celiac Disease Antibodies  >32 publications with IL-21 and Celiac Disease
 Hypersensitivity Antibodies  >29 publications with IL-21 and Hypersensitivity
 Kidney Diseases Antibodies  >28 publications with IL-21 and Kidney Diseases
 Heart Diseases Antibodies  >16 publications with IL-21 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Uncharacterized Tissue Antibodies  >1 publications with IL-21 and Uncharacterized Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions