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IL-2Rbeta elisa kit :: Rat IL-2Rbeta ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2514539
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IL-2Rbeta, ELISA Kit

★Popular Item★
 Also Known As   

Rat IL-2Rbeta (Interleukin-2 Receptor-beta) ELISA Kit

 Product Gene Name   

IL-2Rbeta elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P16297
 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Rat IL-2Rbeta. No significant cross-reactivity or interference between Rat IL-2Rbeta and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat IL-2Rbeta and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    62.5-4000pg/mL
 Sensitivity    Min: 37.5pg/mL; Max: 4000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL-2Rbeta elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL-2Rbeta purchase    MBS2514539 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the IL-2Rbeta, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5-4000pg/mL in biological research samples containing IL-2Rbeta, with an estimated sensitivity of Min: 37.5pg/mL; Max: 4000pg/mL. The ELISA analytical biochemical technique of the MBS2514539 kit is based on IL-2Rbeta antibody-IL-2Rbeta antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL-2Rbeta antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL-2Rbeta. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IL-2Rbeta elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IL-2Rbeta in Rat serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat IL-2Rbeta. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat IL-2Rbeta and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat IL-2Rbeta, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat IL-2Rbeta. You can calculate the concentration of Rat IL-2Rbeta in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of IL-2Rbeta elisa kit    IL-2Rbeta elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2514539. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IL-2Rbeta. It may not necessarily be applicable to this product.
 NCBI GI #    6680427
 NCBI GeneID    16185
 NCBI Accession #    NP_032394.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_008368.4 [Other Products]
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 UniProt Primary Accession #    P16297 [Other Products]
 UniProt Secondary Accession #    Q3TZT2 [Other Products]
 UniProt Related Accession #    P16297 [Other Products]
 Molecular Weight    60,539 Da
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 NCBI Official Full Name    interleukin-2 receptor subunit beta
 NCBI Official Synonym Full Names    interleukin 2 receptor, beta chain
 NCBI Official Symbol    Il2rb [Similar Products]
 NCBI Official Synonym Symbols   
p70; CD122; IL15Rbeta; Il-2Rbeta; IL-15Rbeta; Il-2/15Rbeta
[Similar Products]
 NCBI Protein Information    interleukin-2 receptor subunit beta; IL-15 receptor beta chain; IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; IL-2R subunit beta; IL-2RB; high affinity IL-2 receptor subunit beta; p70-75
 UniProt Protein Name    Interleukin-2 receptor subunit beta
 UniProt Synonym Protein Names   
High affinity IL-2 receptor subunit beta; p70-75; CD_antigen: CD122
 UniProt Gene Name    Il2rb [Similar Products]
 UniProt Synonym Gene Names    IL-2 receptor subunit beta; IL-2R subunit beta; IL-2RB [Similar Products]
 UniProt Entry Name    IL2RB_MOUSE
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 NCBI Summary for IL-2Rbeta    The interleukin 2 receptor is composed of alpha and beta subunits. The beta subunit encoded by this gene is very homologous to the human beta subunit and also shows structural similarity to other cytokine receptors. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL-2Rbeta    IL2RB: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation. Interacts with HTLV-1 accessory protein p12I. Belongs to the type I cytokine receptor family. Type 4 subfamily.

Protein type: Membrane protein, integral; Receptor, cytokine

Cellular Component: cell surface; membrane; integral to membrane; external side of plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-2 receptor activity; interleukin-2 binding

Biological Process: cytokine and chemokine mediated signaling pathway; natural killer cell activation; negative regulation of apoptosis
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 Research Articles on IL-2Rbeta    1. Thymic development of CD4+Foxp3+ regulatory T cells (Tregs) is highly dysregulated in IL-2 receptor (2Rbeta)-deficient mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IL-2Rbeta elisa kitDiseases associated with IL-2Rbeta elisa kit
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 G Beta:gamma Signalling Through PI3Kgamma Pathway antibodies  G Beta:gamma Signalling Through PI3Kgamma Pathway Diagram
 G-protein Beta:gamma Signalling Pathway antibodies  G-protein Beta:gamma Signalling Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPVI-mediated Activation Cascade Pathway antibodies  GPVI-mediated Activation Cascade Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >121 publications with IL-2Rbeta and Inflammation
 Necrosis Antibodies  >80 publications with IL-2Rbeta and Necrosis
 Hypersensitivity Antibodies  >69 publications with IL-2Rbeta and Hypersensitivity
 Lung Diseases Antibodies  >57 publications with IL-2Rbeta and Lung Diseases
 Carcinoma Antibodies  >40 publications with IL-2Rbeta and Carcinoma
 Asthma Antibodies  >40 publications with IL-2Rbeta and Asthma
 Respiratory Hypersensitivity Antibodies  >38 publications with IL-2Rbeta and Respiratory Hypersensitivity
 Arthritis, Rheumatoid Antibodies  >31 publications with IL-2Rbeta and Arthritis, Rheumatoid
 Liver Diseases Antibodies  >25 publications with IL-2Rbeta and Liver Diseases
 Hepatitis Antibodies  >21 publications with IL-2Rbeta and Hepatitis
Organs/Tissues associated with IL-2Rbeta elisa kit
 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >103 publications with IL-2Rbeta and Spleen
 Thymus Antibodies  >75 publications with IL-2Rbeta and Thymus
 Lung Antibodies  >61 publications with IL-2Rbeta and Lung
 Bone Antibodies  >59 publications with IL-2Rbeta and Bone
 Liver Antibodies  >37 publications with IL-2Rbeta and Liver
 Intestine Antibodies  >27 publications with IL-2Rbeta and Intestine
 Pancreas Antibodies  >26 publications with IL-2Rbeta and Pancreas
 Heart Antibodies  >20 publications with IL-2Rbeta and Heart
 Embryonic Tissue Antibodies  >10 publications with IL-2Rbeta and Embryonic Tissue
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