NP_001070968.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,170 Da
NCBI Official Full Name
kallikrein-10 preproprotein
NCBI Official Synonym Full Names
kallikrein-related peptidase 10
NCBI Official Synonym Symbols
NCBI Protein Information
kallikrein-10; protease serine-like 1; kallikrein 10 protein 1; kallikrein 10 protein 2; kallikrein 10 protein 3; kallikrein 10 protein 4; kallikrein 10 protein 7; kallikrein 10 protein 8; kallikrein 10 protein 9; kallikrein 10 protein 12; protease, serine-like, 1; normal epithelial cell-specific 1; breast normal epithelial cell associated serine protease
UniProt Protein Name
Kallikrein-10
UniProt Synonym Protein Names
Normal epithelial cell-specific 1; Protease serine-like 1
UniProt Synonym Gene Names
UniProt Entry Name
KLK10_HUMAN
NCBI Summary for KLK10
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
UniProt Comments for KLK10
KLK10: Has a tumor-suppressor role for NES1 in breast and prostate cancer. Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein type: Secreted, signal peptide; Protease; EC 3.4.21.-; Tumor suppressor; Secreted
Chromosomal Location of Human Ortholog: 19q13
Cellular Component: extracellular region
Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: cell cycle; proteolysis
Research Articles on KLK10
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Products associated with KLK10 elisa kit
Diseases associated with KLK10 elisa kit
Organs/Tissues associated with KLK10 elisa kit
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