NP_001186040.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,628 Da
NCBI Official Full Name
malate dehydrogenase, cytoplasmic isoform 1
NCBI Official Synonym Full Names
malate dehydrogenase 1, NAD (soluble)
NCBI Official Synonym Symbols
MDHA; MOR2; MDH-s; HEL-S-32; MGC:1375 [Similar Products]
NCBI Protein Information
malate dehydrogenase, cytoplasmic; cytosolic malate dehydrogenase; diiodophenylpyruvate reductase; epididymis secretory protein Li 32; soluble malate dehydrogenase
UniProt Protein Name
Malate dehydrogenase, cytoplasmic
UniProt Synonym Protein Names
Cytosolic malate dehydrogenase; Diiodophenylpyruvate reductase (EC:1.1.1.96)
UniProt Synonym Gene Names
UniProt Entry Name
MDHC_HUMAN
NCBI Summary for MDH 1
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Nov 2010]
UniProt Comments for MDH 1
MDH1: Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Nov 2010]
Protein type: Carbohydrate Metabolism - glyoxylate and dicarboxylate; Carbohydrate Metabolism - pyruvate; EC 1.1.1.37; Carbohydrate Metabolism - citrate (TCA) cycle; EC 1.1.1.96; Oxidoreductase
Chromosomal Location of Human Ortholog: 2p13.3
Cellular Component: extracellular space; centrosome; mitochondrion; cytoplasm; cytosol
Molecular Function: malic enzyme activity; L-malate dehydrogenase activity; diiodophenylpyruvate reductase activity; NAD binding
Biological Process: malate metabolic process; oxaloacetate metabolic process; NADH metabolic process; tricarboxylic acid cycle; carbohydrate metabolic process; glucose metabolic process; pathogenesis; cellular carbohydrate metabolic process; gluconeogenesis
Research Articles on MDH 1
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Products associated with MDH 1 elisa kit
Pathways associated with MDH 1 elisa kit
Products by Pathway |
Pathway Diagram |
Carbon Metabolism Pathway antibodies |
Carbon Metabolism Pathway Diagram |
Carbon Metabolism Pathway antibodies |
Carbon Metabolism Pathway Diagram |
Citrate Cycle (TCA Cycle) Pathway antibodies |
Citrate Cycle (TCA Cycle) Pathway Diagram |
Citrate Cycle (TCA Cycle) Pathway antibodies |
Citrate Cycle (TCA Cycle) Pathway Diagram |
Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies |
Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram |
Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies |
Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram |
Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies |
Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram |
Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies |
Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram |
Cysteine And Methionine Metabolism Pathway antibodies |
Cysteine And Methionine Metabolism Pathway Diagram |
Cysteine And Methionine Metabolism Pathway antibodies |
Cysteine And Methionine Metabolism Pathway Diagram |
Diseases associated with MDH 1 elisa kit
Organs/Tissues associated with MDH 1 elisa kit
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