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MIP-3beta/ELC/CCL19 elisa kit :: Rat MIP-3beta ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2503550
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MIP-3beta (MIP-3beta/ELC/CCL19), ELISA Kit

★Popular Item★
 Also Known As   

Rat MIP-3beta(Macrophage Inflammatory Protein 3beta) ELISA Kit

 Product Gene Name   

MIP-3beta/ELC/CCL19 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    602227
 3D Structure    ModBase 3D Structure for Q99731
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Rat MIP-3beta/ELC/CCL19. No significant cross-reactivity or interference between Rat MIP-3beta/ELC/CCL19 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat MIP-3beta/ELC/CCL19 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    15.625-1000pg/mL
 Sensitivity    Min: 9.375pg/mL; Max: 1000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MIP-3beta/ELC/CCL19 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MIP-3beta/ELC/CCL19 purchase    MBS2503550 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the MIP-3beta (MIP-3beta/ELC/CCL19) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.625-1000pg/mL in biological research samples containing MIP-3beta/ELC/CCL19, with an estimated sensitivity of Min: 9.375pg/mL; Max: 1000pg/mL. The ELISA analytical biochemical technique of the MBS2503550 kit is based on MIP-3beta/ELC/CCL19 antibody-MIP-3beta/ELC/CCL19 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MIP-3beta/ELC/CCL19 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MIP-3beta/ELC/CCL19. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for MIP-3beta/ELC/CCL19 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of MIP-3beta/ELC/CCL19 in Rat serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat MIP-3beta/ELC/CCL19. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat MIP-3beta/ELC/CCL19 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat MIP-3beta/ELC/CCL19, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat MIP-3beta/ELC/CCL19. You can calculate the concentration of Rat MIP-3beta/ELC/CCL19 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of MIP-3beta/ELC/CCL19 elisa kit    MIP-3beta/ELC/CCL19 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2503550. Click to request current manual
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NCBI/Uniprot data below describe general gene information for MIP-3beta/ELC/CCL19. It may not necessarily be applicable to this product.
 NCBI GI #    1791003
 NCBI GeneID    6363
 NCBI Accession #    AAC50944.1 [Other Products]
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 UniProt Primary Accession #    Q99731 [Other Products]
 UniProt Secondary Accession #    O00697; O00736 [Other Products]
 UniProt Related Accession #    Q99731 [Other Products]
 Molecular Weight    10,993 Da
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 NCBI Official Full Name    macrophage inflammatory protein 3 beta
 NCBI Official Synonym Full Names    chemokine (C-C motif) ligand 19
 NCBI Official Symbol    CCL19 [Similar Products]
 NCBI Official Synonym Symbols   
ELC; CKb11; MIP3B; MIP-3b; SCYA19
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 19; CC chemokine ligand 19; CK beta-11; EBI1 ligand chemokine; EBI1-ligand chemokine; MIP-3-beta; beta chemokine exodus-3; beta-chemokine exodus-3; epstein-Barr virus-induced molecule 1 ligand chemokine; macrophage inflammatory protein 3 beta; macrophage inflammatory protein 3-beta; small inducible cytokine subfamily A (Cys-Cys), member 19; small-inducible cytokine A19
 UniProt Protein Name    C-C motif chemokine 19
 UniProt Synonym Protein Names   
Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Macrophage inflammatory protein 3 beta; MIP-3-beta; Small-inducible cytokine A19
 UniProt Gene Name    CCL19 [Similar Products]
 UniProt Synonym Gene Names    ELC; MIP3B; SCYA19; EBI1 ligand chemokine; ELC; MIP-3-beta [Similar Products]
 UniProt Entry Name    CCL19_HUMAN
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 NCBI Summary for MIP-3beta/ELC/CCL19    This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]
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 UniProt Comments for MIP-3beta/ELC/CCL19    CCL19: May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9p13

Cellular Component: extracellular space; extracellular region

Molecular Function: CCR chemokine receptor binding; chemokine activity; chemokine receptor binding; CCR10 chemokine receptor binding; CCR7 chemokine receptor binding

Biological Process: formation of immunological synapse; positive regulation of interleukin-12 production; positive regulation of dendritic cell antigen processing and presentation; cell maturation; positive regulation of JNK cascade; positive regulation of endocytosis; positive regulation of NF-kappaB import into nucleus; positive regulation of interleukin-1 beta secretion; activation of JNK activity; positive regulation of receptor-mediated endocytosis; dendritic cell chemotaxis; establishment of T cell polarity; cell communication; positive regulation of T cell proliferation; inflammatory response; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of chemotaxis; response to virus; positive regulation of phosphoinositide 3-kinase activity; positive regulation of tumor necrosis factor production; cellular calcium ion homeostasis; positive regulation of protein kinase B signaling cascade; myeloid dendritic cell chemotaxis; release of sequestered calcium ion into cytosol; positive regulation of protein kinase activity; T cell costimulation; immune response; positive regulation of T-helper 1 cell differentiation
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 Research Articles on MIP-3beta/ELC/CCL19    1. Serum CCL19 and CCL21 were up-regulated during Rickettsia conorii infection.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MIP-3beta/ELC/CCL19 elisa kitPathways associated with MIP-3beta/ELC/CCL19 elisa kit
 Reference Product  PubMed Publications
 CCR7 elisa kit  >442 publications with MIP-3beta/ELC/CCL19 and CCR7
 CXCL13 elisa kit  >99 publications with MIP-3beta/ELC/CCL19 and CXCL13
 CXCL10 elisa kit  >57 publications with MIP-3beta/ELC/CCL19 and CXCL10
 CCR5 elisa kit  >51 publications with MIP-3beta/ELC/CCL19 and CCR5
 CCR6 elisa kit  >47 publications with MIP-3beta/ELC/CCL19 and CCR6
 CXCL9 elisa kit  >37 publications with MIP-3beta/ELC/CCL19 and CXCL9
 CXCR5 elisa kit  >31 publications with MIP-3beta/ELC/CCL19 and CXCR5
 CCL25 elisa kit  >30 publications with MIP-3beta/ELC/CCL19 and CCL25
 CCR1 elisa kit  >24 publications with MIP-3beta/ELC/CCL19 and CCR1
 CXCL11 elisa kit  >21 publications with MIP-3beta/ELC/CCL19 and CXCL11
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
Diseases associated with MIP-3beta/ELC/CCL19 elisa kitOrgans/Tissues associated with MIP-3beta/ELC/CCL19 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >151 publications with MIP-3beta/ELC/CCL19 and Inflammation
 Necrosis Antibodies  >66 publications with MIP-3beta/ELC/CCL19 and Necrosis
 Lung Diseases Antibodies  >44 publications with MIP-3beta/ELC/CCL19 and Lung Diseases
 Vascular Diseases Antibodies  >32 publications with MIP-3beta/ELC/CCL19 and Vascular Diseases
 Hypersensitivity Antibodies  >28 publications with MIP-3beta/ELC/CCL19 and Hypersensitivity
 Death Antibodies  >21 publications with MIP-3beta/ELC/CCL19 and Death
 Lung Neoplasms Antibodies  >14 publications with MIP-3beta/ELC/CCL19 and Lung Neoplasms
 Respiratory Tract Infections Antibodies  >14 publications with MIP-3beta/ELC/CCL19 and Respiratory Tract Infections
 Liver Diseases Antibodies  >13 publications with MIP-3beta/ELC/CCL19 and Liver Diseases
 Heart Diseases Antibodies  >12 publications with MIP-3beta/ELC/CCL19 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >281 publications with MIP-3beta/ELC/CCL19 and Lymph Node
 Vascular Antibodies  >86 publications with MIP-3beta/ELC/CCL19 and Vascular
 Spleen Antibodies  >70 publications with MIP-3beta/ELC/CCL19 and Spleen
 Lung Antibodies  >64 publications with MIP-3beta/ELC/CCL19 and Lung
 Thymus Antibodies  >38 publications with MIP-3beta/ELC/CCL19 and Thymus
 Brain Antibodies  >30 publications with MIP-3beta/ELC/CCL19 and Brain
 Intestine Antibodies  >23 publications with MIP-3beta/ELC/CCL19 and Intestine
 Eye Antibodies  >19 publications with MIP-3beta/ELC/CCL19 and Eye
 Pancreas Antibodies  >17 publications with MIP-3beta/ELC/CCL19 and Pancreas
 Heart Antibodies  >14 publications with MIP-3beta/ELC/CCL19 and Heart
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