NP_005920.2
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
80,215 Da
NCBI Official Full Name
melanotransferrin isoform 1
NCBI Official Synonym Full Names
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
NCBI Protein Information
melanotransferrin; membrane-bound transferrin-like protein; melanoma-associated antigen p97, isoform 2
UniProt Protein Name
Melanotransferrin
UniProt Synonym Protein Names
Melanoma-associated antigen p97
UniProt Synonym Gene Names
UniProt Entry Name
TRFM_HUMAN
NCBI Summary for MFI2
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008]
UniProt Comments for MFI2
MFI2: Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 3q28-q29
Cellular Component: anchored to plasma membrane; cell surface; integral to plasma membrane
Molecular Function: protein binding; ferric iron binding; iron ion binding
Biological Process: cellular iron ion homeostasis; regulation of cell growth; regulation of cell proliferation
Research Articles on MFI2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with MFI2 elisa kit
Organs/Tissues associated with MFI2 elisa kit
|