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MPO-ANCA IgG elisa kit :: Rat Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG ELISA Kit

Scan QR to view Datasheet Catalog #    MBS006216 MPO-ANCA IgG elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG (MPO-ANCA IgG), ELISA Kit

 Also Known As   

Rat Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG ELISA Kit

 Product Gene Name   

MPO-ANCA IgG elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    177020
 3D Structure    ModBase 3D Structure for P24158
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 Species Reactivity    Rat
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MPO-ANCA IgG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MPO-ANCA IgG purchase    MBS006216 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Myeloperoxidase-Antineutrophil Cytoplasmic Antibody IgG (MPO-ANCA IgG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MPO-ANCA IgG. The ELISA analytical biochemical technique of the MBS006216 kit is based on MPO-ANCA IgG antibody-MPO-ANCA IgG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MPO-ANCA IgG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MPO-ANCA IgG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for MPO-ANCA IgG. It may not necessarily be applicable to this product.
 NCBI GI #    71361688
 NCBI GeneID    5657
 NCBI Accession #    NP_002768.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_002777.3 [Other Products]
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 UniProt Primary Accession #    P24158 [Other Products]
 UniProt Secondary Accession #    P15637; P18078; Q4VB08; Q4VB09; Q6LBM7; Q6LBN2; Q9UD25; Q9UQD8 [Other Products]
 UniProt Related Accession #    P24158 [Other Products]
 Molecular Weight    27,807 Da
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 NCBI Official Full Name    myeloblastin
 NCBI Official Synonym Full Names    proteinase 3
 NCBI Official Symbol    PRTN3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    myeloblastin; C-ANCA antigen; wegener autoantigen; leukocyte proteinase 3; neutrophil proteinase 4; azurophil granule protein 7; serine proteinase, neutrophil; Wegener granulomatosis autoantigen
 UniProt Protein Name    Myeloblastin
 UniProt Synonym Protein Names   
AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen
 UniProt Gene Name    PRTN3 [Similar Products]
 UniProt Synonym Gene Names    MBN; PR-3; PR3; NP-4 [Similar Products]
 UniProt Entry Name    PRTN3_HUMAN
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 UniProt Comments for MPO-ANCA IgG    PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily.

Protein type: EC; Cell cycle regulation; Protease

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular matrix; extracellular space; plasma membrane; cytosol

Molecular Function: enzyme binding; serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: collagen catabolic process; negative regulation of phagocytosis; positive regulation of cell proliferation; blood coagulation; proteolysis
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 Research Articles on MPO-ANCA IgG    1. The presence of ANCA in the bile of patients with primary sclerosing cholangitis (PSC) is a novel finding and highly suggestive of PSC. Biliary IgG ANCA correlates with the severity of bile duct strictures.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with MPO-ANCA IgG elisa kitDiseases associated with MPO-ANCA IgG elisa kit
 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >374 publications with MPO-ANCA IgG and Lung Diseases
 Inflammation Antibodies  >152 publications with MPO-ANCA IgG and Inflammation
 Kidney Diseases Antibodies  >122 publications with MPO-ANCA IgG and Kidney Diseases
 Necrosis Antibodies  >78 publications with MPO-ANCA IgG and Necrosis
 Neoplasms Antibodies  >65 publications with MPO-ANCA IgG and Neoplasms
 Disease Models, Animal Antibodies  >36 publications with MPO-ANCA IgG and Disease Models, Animal
 Brain Diseases Antibodies  >32 publications with MPO-ANCA IgG and Brain Diseases
 Lupus Erythematosus, Systemic Antibodies  >31 publications with MPO-ANCA IgG and Lupus Erythematosus, Systemic
 Intestinal Diseases Antibodies  >30 publications with MPO-ANCA IgG and Intestinal Diseases
 Fibrosis Antibodies  >30 publications with MPO-ANCA IgG and Fibrosis
Organs/Tissues associated with MPO-ANCA IgG elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >641 publications with MPO-ANCA IgG and Blood
 Bone Marrow Antibodies  >26 publications with MPO-ANCA IgG and Bone Marrow
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