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NOX 1 elisa kit :: Rat NOX1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2508743
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NOX1 (NOX 1), ELISA Kit

★Popular Item★
 Also Known As   

Rat NOX1 (Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1) ELISA Kit

 Product Gene Name   

NOX 1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    300225
 3D Structure    ModBase 3D Structure for Q9Y5S8
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Rat NOX 1. No significant cross-reactivity or interference between Rat NOX 1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat NOX 1 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.313--20ng/mL
 Sensitivity    0.188ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NOX 1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NOX 1 purchase    MBS2508743 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the NOX1 (NOX 1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313--20ng/mL in biological research samples containing NOX 1, with an estimated sensitivity of 0.188ng/mL. The ELISA analytical biochemical technique of the MBS2508743 kit is based on NOX 1 antibody-NOX 1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NOX 1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NOX 1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for NOX 1 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of NOX 1 in Rat serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat NOX 1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat NOX 1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat NOX 1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat NOX 1. You can calculate the concentration of Rat NOX 1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of NOX 1 elisa kit    NOX 1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2508743. Click to request current manual
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NCBI/Uniprot data below describe general gene information for NOX 1. It may not necessarily be applicable to this product.
 NCBI GI #    425854820
 NCBI GeneID    27035
 NCBI Accession #    NP_001258744.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001271815.1 [Other Products]
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 UniProt Primary Accession #    Q9Y5S8 [Other Products]
 UniProt Secondary Accession #    O95691; Q2PP02; A8K836 [Other Products]
 UniProt Related Accession #    Q9Y5S8 [Other Products]
 Molecular Weight    58,972 Da
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 NCBI Official Full Name    NADPH oxidase 1 isoform 3
 NCBI Official Synonym Full Names    NADPH oxidase 1
 NCBI Official Symbol    NOX1 [Similar Products]
 NCBI Official Synonym Symbols   
MOX1; NOH1; NOH-1; GP91-2
[Similar Products]
 NCBI Protein Information    NADPH oxidase 1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase homolog-1; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1
 UniProt Protein Name    NADPH oxidase 1
 UniProt Synonym Protein Names   
Mitogenic oxidase 1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NOH-1
 UniProt Gene Name    NOX1 [Similar Products]
 UniProt Synonym Gene Names    MOX1; NOH1; NOX-1; MOX-1 [Similar Products]
 UniProt Entry Name    NOX1_HUMAN
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 NCBI Summary for NOX 1    This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
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 UniProt Comments for NOX 1    NOX1: NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; EC 1.-.-.-; Membrane protein, integral; Oxidoreductase; Channel, misc.; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: Xq22

Cellular Component: early endosome; integral to membrane; cell junction; NADPH oxidase complex

Molecular Function: protein binding; metal ion binding; superoxide-generating NADPH oxidase activity; Rac GTPase binding; NADP binding; voltage-gated proton channel activity

Biological Process: intracellular pH elevation; respiratory burst; cell migration; extracellular matrix organization and biogenesis; positive regulation of smooth muscle cell proliferation; superoxide metabolic process; positive regulation of JNK cascade; signal transduction; NADP metabolic process; regulation of systemic arterial blood pressure by renin-angiotensin; proton transport; regulation of blood pressure; positive regulation of cell proliferation; hydrogen peroxide metabolic process; positive regulation of integrin biosynthetic process; angiogenesis; inflammatory response; superoxide release
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 Research Articles on NOX 1    1. Elevated ROS derived from NOX1 activation and downregulation of SOD in NIH3T3RET-MEN2A and NIH3T3RET-MEN 2B cells may be involved in RET constitutive tyrosine auto-phosphorylation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NOX 1 elisa kitPathways associated with NOX 1 elisa kit
 Reference Product  PubMed Publications
 RAC1 elisa kit  >83 publications with NOX 1 and RAC1
 NOXO1 elisa kit  >71 publications with NOX 1 and NOXO1
 NOXA1 elisa kit  >64 publications with NOX 1 and NOXA1
 CYBA elisa kit  >39 publications with NOX 1 and CYBA
 MMP9 elisa kit  >4 publications with NOX 1 and MMP9
 RAC3 elisa kit  >2 publications with NOX 1 and RAC3
 MMP2 elisa kit  >1 publications with NOX 1 and MMP2
 VCAM1 elisa kit  >1 publications with NOX 1 and VCAM1
 Products by Pathway  Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 RAC1 Signaling Pathway antibodies  RAC1 Signaling Pathway Diagram
Diseases associated with NOX 1 elisa kitOrgans/Tissues associated with NOX 1 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >145 publications with NOX 1 and Cardiovascular Diseases
 Inflammation Antibodies  >109 publications with NOX 1 and Inflammation
 Hypertension Antibodies  >102 publications with NOX 1 and Hypertension
 Atherosclerosis Antibodies  >63 publications with NOX 1 and Atherosclerosis
 Necrosis Antibodies  >51 publications with NOX 1 and Necrosis
 Heart Diseases Antibodies  >50 publications with NOX 1 and Heart Diseases
 Hypertrophy Antibodies  >47 publications with NOX 1 and Hypertrophy
 Fibrosis Antibodies  >38 publications with NOX 1 and Fibrosis
 Nervous System Diseases Antibodies  >37 publications with NOX 1 and Nervous System Diseases
 Intestinal Diseases Antibodies  >25 publications with NOX 1 and Intestinal Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >35 publications with NOX 1 and Brain
 Intestine Antibodies  >34 publications with NOX 1 and Intestine
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