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Lcn2 elisa kit :: Rat Neutrophil gelatinase-associated lipocalin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2884287 Lcn2 elisa kit
Unit / Price
48-Strip-Wells  /  $325 +1 FREE 8GB USB
96-Strip-Wells  /  $435 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,290 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Neutrophil gelatinase-associated lipocalin (Lcn2), ELISA Kit

★Popular Item★
 Also Known As   

Rat Neutrophil gelatinase-associated lipocalin ELISA Kit

 Product Synonym Names    Neutrophil gelatinase-associated lipocalin; NGAL; Alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; Lipocalin-2; p25; Lcn2; p25
 Product Gene Name   

Lcn2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P30152
 Species Reactivity    Rat
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 Assay Type    Sandwich
 Detection Range    0.78-50 ng/ml
 Sensitivity    0.46 ng/mL
 Intra-Assay CV    <=5.2%
 Inter-Assay CV    <=7.4%
 Recovery    91%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Lcn2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Lcn2 purchase    MBS2884287 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Neutrophil gelatinase-associated lipocalin (Lcn2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.78-50 ng/ml in biological research samples containing Lcn2, with an estimated sensitivity of 0.46 ng/mL. The ELISA analytical biochemical technique of the MBS2884287 kit is based on Lcn2 antibody-Lcn2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Lcn2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Lcn2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Lcn2. It may not necessarily be applicable to this product.
 NCBI GI #    18543345
 NCBI GeneID    170496
 NCBI Accession #    NP_570097.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_130741.1 [Other Products]
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 UniProt Primary Accession #    P30152 [Other Products]
 UniProt Secondary Accession #    Q5HZF1 [Other Products]
 UniProt Related Accession #    P30152 [Other Products]
 Molecular Weight    22,476 Da
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 NCBI Official Full Name    neutrophil gelatinase-associated lipocalin
 NCBI Official Synonym Full Names    lipocalin 2
 NCBI Official Symbol    Lcn2 [Similar Products]
 NCBI Official Synonym Symbols   
Sip24
[Similar Products]
 NCBI Protein Information    neutrophil gelatinase-associated lipocalin
 UniProt Protein Name    Neutrophil gelatinase-associated lipocalin
 UniProt Synonym Protein Names   
Alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; Lipocalin-2; Siderocalin LCN2; p25
 Protein Family    Neutrophil gelatinase-associated lipocalin
 UniProt Gene Name    Lcn2 [Similar Products]
 UniProt Synonym Gene Names    NGAL [Similar Products]
 UniProt Entry Name    NGAL_RAT
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 NCBI Summary for Lcn2    mouse homolog plays a role in IL3 withdrawal-induced apoptosis [RGD, Feb 2006]
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 UniProt Comments for Lcn2    LCN2: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth. Belongs to the calycin superfamily. Lipocalin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Transporter; Secreted; Secreted, signal peptide

Cellular Component: cytosol; extracellular region; extracellular space

Molecular Function: iron ion binding; protease binding; protein homodimerization activity; transporter activity

Biological Process: cellular response to nutrient levels; innate immune response; ion transport; iron ion homeostasis; positive regulation of cell projection organization and biogenesis; response to bacterium; response to drug; response to herbicide; response to mycotoxin; response to nutrient levels; response to oxidative stress; response to virus; siderophore transport
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 Research Articles on Lcn2    1. Data show a strong correlation has been detected between peroxisome proliferator-activated receptor gamma (PPAR-gamma), neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (Kappaim-1) and interleukappain-1 in cilostazol renoprotective effect.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Lcn2 elisa kitPathways associated with Lcn2 elisa kit
 Reference Product  PubMed Publications
 Mmp9 elisa kit  >33 publications with Lcn2 and Mmp9
 Hmox1 elisa kit  >19 publications with Lcn2 and Hmox1
 Erbb2 elisa kit  >10 publications with Lcn2 and Erbb2
 Vegfa elisa kit  >2 publications with Lcn2 and Vegfa
 Il17a elisa kit  >2 publications with Lcn2 and Il17a
 Cdh1 elisa kit  >1 publications with Lcn2 and Cdh1
 Vegp1 elisa kit  >1 publications with Lcn2 and Vegp1
 Products by Pathway  Pathway Diagram
 Iron Uptake And Transport Pathway antibodies  Iron Uptake And Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with Lcn2 elisa kitOrgans/Tissues associated with Lcn2 elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >759 publications with Lcn2 and Kidney Diseases
 Acute Kidney Injury Antibodies  >692 publications with Lcn2 and Acute Kidney Injury
 Inflammation Antibodies  >342 publications with Lcn2 and Inflammation
 Cardiovascular Diseases Antibodies  >261 publications with Lcn2 and Cardiovascular Diseases
 Heart Diseases Antibodies  >139 publications with Lcn2 and Heart Diseases
 Necrosis Antibodies  >112 publications with Lcn2 and Necrosis
 Proteinuria Antibodies  >106 publications with Lcn2 and Proteinuria
 Disease Models, Animal Antibodies  >105 publications with Lcn2 and Disease Models, Animal
 Renal Insufficiency, Chronic Antibodies  >98 publications with Lcn2 and Renal Insufficiency, Chronic
 Hypertension Antibodies  >93 publications with Lcn2 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >175 publications with Lcn2 and Liver
 Heart Antibodies  >170 publications with Lcn2 and Heart
 Lung Antibodies  >88 publications with Lcn2 and Lung
 Connective Tissue Antibodies  >42 publications with Lcn2 and Connective Tissue
 Pancreas Antibodies  >14 publications with Lcn2 and Pancreas
 Eye Antibodies  >13 publications with Lcn2 and Eye
 Spleen Antibodies  >13 publications with Lcn2 and Spleen
 Ovary Antibodies  >11 publications with Lcn2 and Ovary
 Cervix Antibodies  >6 publications with Lcn2 and Cervix
 Uncharacterized Tissue Antibodies  >1 publications with Lcn2 and Uncharacterized Tissue
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