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NRF2 elisa kit :: Nuclear respiratory factor 2 (NRF2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS706836
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Nuclear respiratory factor 2 (NRF2), ELISA Kit

★Popular Item★
 Also Known As   

Rat Nuclear respiratory factor 2, NRF2 ELISA Kit

 Product Synonym Names    Rat Nuclear respiratory factor 2 (NRF2) ELISA kit; Nuclear respiratory factor 2 (NRF2)
 Product Gene Name   

NRF2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS706836 Testing Data    Testing Data PDF
 OMIM    600879
 3D Structure    ModBase 3D Structure for Q16656
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of rat NRF2. No significant cross-reactivity or interference between rat NRF2 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell lysates
 Detection Range    34.4 pg/ml-2200 pg/mL
 Sensitivity    <8.6 pg/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NRF2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NRF2 purchase    MBS706836 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Nuclear respiratory factor 2 (NRF2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 34.4 pg/ml-2200 pg/mL in biological research samples containing NRF2, with an estimated sensitivity of <8.6 pg/mL. The ELISA analytical biochemical technique of the MBS706836 kit is based on NRF2 antibody-NRF2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NRF2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NRF2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for NRF2 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for NRF2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any NRF2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for NRF2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of NRF2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of NRF2 elisa kit    NRF2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS706836. Click to request current manual
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NCBI/Uniprot data below describe general gene information for NRF2. It may not necessarily be applicable to this product.
 NCBI GI #    93141039
 NCBI GeneID    4899
 NCBI Accession #    NP_001035199.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001040110.1 [Other Products]
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 UniProt Primary Accession #    Q16656 [Other Products]
 UniProt Secondary Accession #    Q15305; Q96AN2; A8K4C6; B4DDV6 [Other Products]
 UniProt Related Accession #    Q16656 [Other Products]
 Molecular Weight    55,674 Da
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 NCBI Official Full Name    nuclear respiratory factor 1 isoform 1
 NCBI Official Synonym Full Names    nuclear respiratory factor 1
 NCBI Official Symbol    NRF1 [Similar Products]
 NCBI Official Synonym Symbols   
ALPHA-PAL
[Similar Products]
 NCBI Protein Information    nuclear respiratory factor 1; alpha palindromic-binding protein
 UniProt Protein Name    Nuclear respiratory factor 1
 UniProt Synonym Protein Names   
Alpha palindromic-binding protein; Alpha-pal
 UniProt Gene Name    NRF1 [Similar Products]
 UniProt Synonym Gene Names    NRF-1; Alpha-pal [Similar Products]
 UniProt Entry Name    NRF1_HUMAN
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 NCBI Summary for NRF2    This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]
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 UniProt Comments for NRF2    Function: Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
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 Research Articles on NRF2    1. Low NRF1 expression is associated with chronic kidney disease after dialysis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NRF2 elisa kitPathways associated with NRF2 elisa kit
 Reference Product  PubMed Publications
 TFAM elisa kit  >102 publications with NRF2 and TFAM
 PPARGC1A elisa kit  >58 publications with NRF2 and PPARGC1A
 UCP2 elisa kit  >7 publications with NRF2 and UCP2
 TOMM20 elisa kit  >3 publications with NRF2 and TOMM20
 AKT1 elisa kit  >2 publications with NRF2 and AKT1
 MEF2A elisa kit  >2 publications with NRF2 and MEF2A
 PPRC1 elisa kit  >2 publications with NRF2 and PPRC1
 SPAST elisa kit  >1 publications with NRF2 and SPAST
 PARP1 elisa kit  >1 publications with NRF2 and PARP1
 Products by Pathway  Pathway Diagram
 Energy Metabolism Pathway antibodies  Energy Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Mitochondrial Gene Expression Pathway antibodies  Mitochondrial Gene Expression Pathway Diagram
 Mitochondrial Biogenesis Pathway antibodies  Mitochondrial Biogenesis Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
Diseases associated with NRF2 elisa kitOrgans/Tissues associated with NRF2 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >26 publications with NRF2 and Nervous System Diseases
 Insulin Resistance Antibodies  >20 publications with NRF2 and Insulin Resistance
 Diabetes Mellitus Antibodies  >19 publications with NRF2 and Diabetes Mellitus
 Liver Diseases Antibodies  >19 publications with NRF2 and Liver Diseases
 Inflammation Antibodies  >17 publications with NRF2 and Inflammation
 Fatty Liver Antibodies  >16 publications with NRF2 and Fatty Liver
 Cardiovascular Diseases Antibodies  >15 publications with NRF2 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >14 publications with NRF2 and Disease Models, Animal
 Necrosis Antibodies  >14 publications with NRF2 and Necrosis
 Anemia Antibodies  >9 publications with NRF2 and Anemia
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >39 publications with NRF2 and Liver
 Blood Antibodies  >24 publications with NRF2 and Blood
 Brain Antibodies  >23 publications with NRF2 and Brain
 Heart Antibodies  >22 publications with NRF2 and Heart
 Lung Antibodies  >12 publications with NRF2 and Lung
 Kidney Antibodies  >11 publications with NRF2 and Kidney
 Skin Antibodies  >11 publications with NRF2 and Skin
 Nerve Antibodies  >9 publications with NRF2 and Nerve
 Embryonic Tissue Antibodies  >8 publications with NRF2 and Embryonic Tissue
 Eye Antibodies  >7 publications with NRF2 and Eye
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