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OC/BGP elisa kit :: Rat OC/BGP ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2501223 (SPECIAL PROMOTIONAL PRICING for a limited time) OC/BGP elisa kit
Unit / Price
48-Strip-Wells  /  $310 +1 FREE 8GB USB
96-Strip-Wells  /  $355 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,435 +1 FREE 8GB USB
10x96-Strip-Wells  /  $2,805 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

OC/BGP, ELISA Kit

★Popular Item★
 Also Known As   

Rat OC/BGP (Osteocalcin) ELISA Kit

 Product Gene Name   

OC/BGP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2501223 COA    COA PDF
 OMIM    112260
 3D Structure    ModBase 3D Structure for P02818
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 Species Reactivity    Rat
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 Specificity    This kit recognizes natural and recombinantRatOC/BGP. No significant cross-reactivity or interference between RatOC/BGP and analogues was observed.
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 Samples    Serum, plasma and other biological fluids.
 Assay Type    Quantitative Sandwich
 Sensitivity    0.469ng/mL
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 Preparation and Storage    Store at 4 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of OC/BGP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for OC/BGP purchase    MBS2501223 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the OC/BGP, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing OC/BGP, with an estimated sensitivity of 0.469ng/mL. The ELISA analytical biochemical technique of the MBS2501223 kit is based on OC/BGP antibody-OC/BGP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OC/BGP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OC/BGP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for OC/BGP elisa kit

   Intended Uses: This ELISA kit applies to the invitro quantitative determination of RatOC/BGPconcentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to OC/BGP. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for OC/BGPand Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain OC/BGP, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm 2 nm. The OD value is proportional to the concentration of OC/BGP.You can calculate the concentration of OC/BGPin the samples by comparing the OD of the samples to the standard curve.
Sample Manual Insert of MBS2501223. Click to request current manual
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NCBI/Uniprot data below describe general gene information for OC/BGP. It may not necessarily be applicable to this product.
 NCBI GI #    40316933
 NCBI GeneID    632
 NCBI Accession #    NP_954642.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_199173.4 [Other Products]
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 UniProt Primary Accession #    P02818 [Other Products]
 UniProt Secondary Accession #    Q5TCK6 [Other Products]
 UniProt Related Accession #    P02818 [Other Products]
 Molecular Weight    10,963 Da
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 NCBI Official Full Name    osteocalcin preproprotein
 NCBI Official Synonym Full Names    bone gamma-carboxyglutamate (gla) protein
 NCBI Official Symbol    BGLAP [Similar Products]
 NCBI Official Synonym Symbols   
OC; BGP; OCN
[Similar Products]
 NCBI Protein Information    osteocalcin; bone Gla protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); gamma-carboxyglutamic acid-containing protein
 UniProt Protein Name    Osteocalcin
 UniProt Synonym Protein Names   
Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
 UniProt Gene Name    BGLAP [Similar Products]
 UniProt Synonym Gene Names    BGP [Similar Products]
 UniProt Entry Name    OSTCN_HUMAN
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 NCBI Summary for OC/BGP    This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
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 UniProt Comments for OC/BGP    osteocalcin: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Belongs to the osteocalcin/matrix Gla protein family.

Protein type: Secreted; Cell development/differentiation; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: Golgi apparatus; extracellular space; rough endoplasmic reticulum; cytoplasm; dendrite; perikaryon

Molecular Function: structural constituent of bone; hydroxyapatite binding; calcium ion binding; structural molecule activity

Biological Process: response to drug; response to gravity; regulation of bone resorption; response to glucocorticoid stimulus; cell aging; response to testosterone stimulus; bone mineralization; osteoblast development; osteoblast differentiation; odontogenesis; response to vitamin D; regulation of osteoclast differentiation; response to ethanol; response to vitamin K; response to zinc ion; response to estrogen stimulus; response to mechanical stimulus; response to hydroxyisoflavone; response to activity; cell adhesion; regulation of bone mineralization; skeletal development
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 Research Articles on OC/BGP    1. Osteocalcin might improve glucose metabolism through enhancing insulin secretion in males, and through increasing insulin secretion and improving insulin resistance in females with type 2 diabetes mellitus.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OC/BGP elisa kitPathways associated with OC/BGP elisa kit
 Reference Product  PubMed Publications
 RUNX2 elisa kit  >41 publications with OC/BGP and RUNX2
 BMP2 elisa kit  >13 publications with OC/BGP and BMP2
 VDR elisa kit  >4 publications with OC/BGP and VDR
 TGFB1 elisa kit  >3 publications with OC/BGP and TGFB1
 PTH elisa kit  >2 publications with OC/BGP and PTH
 ATF4 elisa kit  >2 publications with OC/BGP and ATF4
 LEP elisa kit  >1 publications with OC/BGP and LEP
 PTHLH elisa kit  >1 publications with OC/BGP and PTHLH
 Products by Pathway  Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram
 Glucocorticoid Receptor Regulatory Network Pathway antibodies  Glucocorticoid Receptor Regulatory Network Pathway Diagram
 Interleukin-11 Signaling Pathway antibodies  Interleukin-11 Signaling Pathway Diagram
 Notch-mediated HES/HEY Network Pathway antibodies  Notch-mediated HES/HEY Network Pathway Diagram
 Regulation Of Retinoblastoma Protein Pathway antibodies  Regulation Of Retinoblastoma Protein Pathway Diagram
 Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway antibodies  Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway Diagram
Diseases associated with OC/BGP elisa kitOrgans/Tissues associated with OC/BGP elisa kit
 Disease Name  Pubmed Publications
 Osteoporosis Antibodies  >9 publications with OC/BGP and Osteoporosis
 Bone Diseases Antibodies  >9 publications with OC/BGP and Bone Diseases
 Inflammation Antibodies  >5 publications with OC/BGP and Inflammation
 Nervous System Diseases Antibodies  >4 publications with OC/BGP and Nervous System Diseases
 Calcinosis Antibodies  >3 publications with OC/BGP and Calcinosis
 Kidney Diseases Antibodies  >2 publications with OC/BGP and Kidney Diseases
 Cardiovascular Diseases Antibodies  >2 publications with OC/BGP and Cardiovascular Diseases
 Pain Antibodies  >2 publications with OC/BGP and Pain
 Renal Insufficiency Antibodies  >1 publications with OC/BGP and Renal Insufficiency
 Hypertension Antibodies  >1 publications with OC/BGP and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >84 publications with OC/BGP and Bone
 Brain Antibodies  >3 publications with OC/BGP and Brain
 Parathyroid Antibodies  >2 publications with OC/BGP and Parathyroid
 Prostate Antibodies  >2 publications with OC/BGP and Prostate
 Lung Antibodies  >1 publications with OC/BGP and Lung
 Heart Antibodies  >1 publications with OC/BGP and Heart
 Intestine Antibodies  >1 publications with OC/BGP and Intestine
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