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OXTR elisa kit :: Rat Oxytocin Receptor (OXTR) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2024520 (SPECIAL PROMOTION: Get FREE Starbucks gift card ($5 for 48-Wells-Kit or $10 for 96-Wells-Kit. Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells  /  $285 +1 FREE 8GB USB
48-Strip-Wells  /  $530 +1 FREE 8GB USB
96-Strip-Wells  /  $715 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,910 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,280 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Oxytocin Receptor (OXTR), ELISA Kit

★Popular Item★
 Also Known As   

Oxytocin Receptor (OXTR) ELISA Kit

 Product Synonym Names    OT-R
 Product Gene Name   

OXTR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    167055
 3D Structure    ModBase 3D Structure for P30559
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Oxytocin Receptor (OXTR).
No significant cross-reactivity or interference between Oxytocin Receptor (OXTR) and analogues was observed.
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 Assay Type    Double-antibody Sandwich
 Samples    Tissue homogenates, Cell lysates and Other Biological Fluids
 Detection Range    0.156-10ng/mL
 Sensitivity    < 0.058ng/mL
 Application    Enzyme-linked immunosorbent assay for Antigen Detection.
 Intra-assay Precision (Precision within an assay)    3 samples with low, middle and high level Oxytocin Receptor (OXTR) were tested 20 times on one plate, respectively.
 Inter-assay Precision (Precision between assays)    3 samples with low, middle and high level Oxytocin Receptor (OXTR) were tested on 3 different plates, 8 replicates in each plate.
 CV(%) =    SD/meanX100
 Intra-Assay    CV<10%
 Inter-Assay    CV<12%
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 Preparation and Storage    The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of OXTR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for OXTR purchase    MBS2024520 is a ready-to-use microwell, strip plate Double-antibody Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Oxytocin Receptor (OXTR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing OXTR, with an estimated sensitivity of < 0.058ng/mL. The ELISA analytical biochemical technique of the MBS2024520 kit is based on OXTR antibody-OXTR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OXTR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OXTR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Tissue homogenates, Cell lysates and Other Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for OXTR elisa kit

   The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Oxytocin Receptor (OXTR). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Oxytocin Receptor (OXTR). Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Oxytocin Receptor (OXTR), biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Oxytocin Receptor (OXTR) in the samples is then determined by comparing the O.D. of the samples to the standard curve.
 Product Categories/Family for OXTR elisa kit    Reproductive science
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 Typical Testing Data/Standard Curve (for reference only) of OXTR elisa kit    OXTR elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2024520. Click to request current manual
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NCBI/Uniprot data below describe general gene information for OXTR. It may not necessarily be applicable to this product.
 NCBI GI #    32307152
 NCBI GeneID    5021
 NCBI Accession #    NP_000907.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000916.3 [Other Products]
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 UniProt Primary Accession #    P30559 [Other Products]
 UniProt Secondary Accession #    Q15071 [Other Products]
 UniProt Related Accession #    P30559 [Other Products]
 Molecular Weight    42,772 Da
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 NCBI Official Full Name    oxytocin receptor
 NCBI Official Synonym Full Names    oxytocin receptor
 NCBI Official Symbol    OXTR [Similar Products]
 NCBI Official Synonym Symbols   
OT-R
[Similar Products]
 NCBI Protein Information    oxytocin receptor
 UniProt Protein Name    Oxytocin receptor
 Protein Family    Oxytocin receptor
 UniProt Gene Name    OXTR [Similar Products]
 UniProt Synonym Gene Names    OT-R [Similar Products]
 UniProt Entry Name    OXYR_HUMAN
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 NCBI Summary for OXTR    The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008]
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 UniProt Comments for OXTR    OXTR: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 3p25

Cellular Component: microvillus; cell-cell adherens junction; integral to plasma membrane; apical plasma membrane; plasma membrane

Molecular Function: oxytocin receptor activity; peptide hormone binding; peptide binding; vasopressin receptor activity

Biological Process: lactation; response to peptide hormone stimulus; response to anoxia; heart development; female pregnancy; positive regulation of synaptic transmission, glutamatergic; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; muscle contraction; response to drug; maternal behavior; eating behavior; response to amphetamine; positive regulation of synaptic transmission, GABAergic; social behavior; response to cocaine; sleep; memory; cellular response to hormone stimulus; positive regulation of synaptogenesis; G-protein coupled receptor protein signaling pathway; telencephalon development; gut development; suckling behavior; regulation of systemic arterial blood pressure by vasopressin; response to cytokine stimulus; maternal process involved in parturition; positive regulation of vasoconstriction; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure
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 Research Articles on OXTR    1. Study identified, in OXTR and AVPR1A genes, signatures of balancing selection in the cis-regulative acting sequences such as transcription factor binding and enhancer sequences, as well as in a transcriptional repressor sequence motif. Additionally, in the intron 3 of the OXTR gene, the SNP rs59190448 appears to be under positive directional selection.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OXTR elisa kitPathways associated with OXTR elisa kit
 Reference Product  PubMed Publications
 OXT elisa kit  >63 publications with OXTR and OXT
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
Diseases associated with OXTR elisa kitOrgans/Tissues associated with OXTR elisa kit
 Disease Name  Pubmed Publications
 Child Development Disorders, Pervasive Antibodies  >34 publications with OXTR and Child Development Disorders, Pervasive
 Autistic Disorder Antibodies  >30 publications with OXTR and Autistic Disorder
 Cognition Disorders Antibodies  >17 publications with OXTR and Cognition Disorders
 Schizophrenia Antibodies  >10 publications with OXTR and Schizophrenia
 Inflammation Antibodies  >8 publications with OXTR and Inflammation
 Depressive Disorder Antibodies  >8 publications with OXTR and Depressive Disorder
 Pain Antibodies  >5 publications with OXTR and Pain
 Pancreatic Neoplasms Antibodies  >4 publications with OXTR and Pancreatic Neoplasms
 Disease Models, Animal Antibodies  >4 publications with OXTR and Disease Models, Animal
 Necrosis Antibodies  >3 publications with OXTR and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >107 publications with OXTR and Brain
 Uterus Antibodies  >28 publications with OXTR and Uterus
 Heart Antibodies  >6 publications with OXTR and Heart
 Connective Tissue Antibodies  >6 publications with OXTR and Connective Tissue
 Embryonic Tissue Antibodies  >5 publications with OXTR and Embryonic Tissue
 Ovary Antibodies  >4 publications with OXTR and Ovary
 Liver Antibodies  >3 publications with OXTR and Liver
 Lung Antibodies  >2 publications with OXTR and Lung
 Kidney Antibodies  >2 publications with OXTR and Kidney
 Skin Antibodies  >2 publications with OXTR and Skin
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