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Plg elisa kit :: Rat Plasminogen ELISA Kit

Scan QR to view Datasheet Catalog #    MBS764997
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $280 +1 FREE 8GB USB
96-Strip-Wells  /  $375 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,015 +3 FREE 8GB USB
15x96-Strip-Wells  /  $4,285 +5 FREE 8GB USB
25x96-Strip-Wells  /  $6,715 +8 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Plasminogen (Plg), ELISA Kit

★Popular Item★
 Also Known As   

Rat Plasminogen ELISA Kit

 Product Synonym Names    Plg
 Product Gene Name   

Plg elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS764997 QC Report    QC Report PDF
 OMIM    173350
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Plg . No significant crossreactivity or interference between Plg and analogues was observed.
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 Samples    Serum, plasma and other biological fluids.
 Assay Type    Sandwich ELISA, Double Antibody
 Detection Range    7.813-500ng/ml
 Sensitivity    4.688ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level Plg were tested 20 times on one plate, respectively. Intra-Assay: CV<8%
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level Plg were tested on 3 different plates, 8 replicates in each plate. CV (%) = SD/meanX100. Inter-Assay: CV<10%
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 Preparation and Storage    Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Plg elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Plg purchase    MBS764997 is a ready-to-use microwell, strip plate Sandwich, Double Antibody ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Plasminogen (Plg) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 7.813-500ng/ml in biological research samples containing Plg, with an estimated sensitivity of 4.688ng/ml. The ELISA analytical biochemical technique of the MBS764997 kit is based on Plg antibody-Plg antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Plg antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Plg. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of Plg elisa kit    Plg elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS764997. Click to request current manual
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NCBI/Uniprot data below describe general gene information for Plg. It may not necessarily be applicable to this product.
 NCBI GI #    190026
 NCBI GeneID    5340
 NCBI Accession #    AAA36451.1 [Other Products]
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 UniProt Secondary Accession #    Q15146; Q5TEH4; Q6PA00 [Other Products]
 UniProt Related Accession #    P00747 [Other Products]
 Molecular Weight    90,569 Da
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 NCBI Official Full Name    plasminogen
 NCBI Official Synonym Full Names    plasminogen
 NCBI Official Symbol    PLG [Similar Products]
 NCBI Protein Information    plasminogen
 UniProt Protein Name    Plasminogen
 Protein Family    Plasminogen
 UniProt Gene Name    PLG [Similar Products]
 UniProt Entry Name    PLMN_HUMAN
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 NCBI Summary for Plg    The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
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 UniProt Comments for Plg    Plasminogen: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Defects in PLG are the cause of plasminogen deficiency (PLGD). PLGD is characterized by decreased serum plasminogen activity. Two forms of the disorder are distinguished: type 1 deficiency is additionally characterized by decreased plasminogen antigen levels and clinical symptoms, whereas type 2 deficiency, also known as dysplasminogenemia, is characterized by normal, or slightly reduced antigen levels, and absence of clinical manifestations. Plasminogen deficiency type 1 results in markedly impaired extracellular fibrinolysis and chronic mucosal pseudomembranous lesions due to subepithelial fibrin deposition and inflammation. The most common clinical manifestation of type 1 deficiency is ligneous conjunctivitis in which pseudomembranes formation on the palpebral surfaces of the eye progresses to white, yellow-white, or red thick masses with a wood-like consistency that replace the normal mucosa. Belongs to the peptidase S1 family. Plasminogen subfamily.

Protein type: EC 3.4.21.7; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6q26

Cellular Component: cell surface; extracellular region; extracellular space; extrinsic to external side of plasma membrane; plasma membrane

Molecular Function: apolipoprotein binding; protein binding; protein domain specific binding; receptor binding; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: blood coagulation; cellular protein metabolic process; extracellular matrix disassembly; fibrinolysis; negative regulation of cell proliferation; negative regulation of fibrinolysis; platelet degranulation; positive regulation of fibrinolysis

Disease: Plasminogen Deficiency, Type I
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 Research Articles on Plg    1. Plasmin cleavage of iC3b provides a complement regulatory pathway that is as efficient as FI/CR1 but does not require a cellular cofactor.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Plg elisa kitPathways associated with Plg elisa kit
 Reference Product  PubMed Publications
 SERPINC1 elisa kit  >58 publications with Plg and SERPINC1
 MMP9 elisa kit  >8 publications with Plg and MMP9
 SPARC elisa kit  >2 publications with Plg and SPARC
 KNG1 elisa kit  >1 publications with Plg and KNG1
 SERPINE1 elisa kit  >1 publications with Plg and SERPINE1
 Products by Pathway  Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
 Blood Clotting Cascade Pathway antibodies  Blood Clotting Cascade Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Dissolution Of Fibrin Clot Pathway antibodies  Dissolution Of Fibrin Clot Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with Plg elisa kitOrgans/Tissues associated with Plg elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >116 publications with Plg and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >92 publications with Plg and Nervous System Diseases
 Thrombosis Antibodies  >87 publications with Plg and Thrombosis
 Inflammation Antibodies  >53 publications with Plg and Inflammation
 Liver Diseases Antibodies  >39 publications with Plg and Liver Diseases
 Blood Coagulation Disorders Antibodies  >35 publications with Plg and Blood Coagulation Disorders
 Hemorrhage Antibodies  >26 publications with Plg and Hemorrhage
 Necrosis Antibodies  >21 publications with Plg and Necrosis
 Venous Thrombosis Antibodies  >20 publications with Plg and Venous Thrombosis
 Heart Diseases Antibodies  >20 publications with Plg and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >437 publications with Plg and Blood
 Brain Antibodies  >122 publications with Plg and Brain
 Liver Antibodies  >80 publications with Plg and Liver
 Lung Antibodies  >50 publications with Plg and Lung
 Spleen Antibodies  >30 publications with Plg and Spleen
 Heart Antibodies  >27 publications with Plg and Heart
 Embryonic Tissue Antibodies  >21 publications with Plg and Embryonic Tissue
 Kidney Antibodies  >21 publications with Plg and Kidney
 Pancreas Antibodies  >4 publications with Plg and Pancreas
 Mammary Gland Antibodies  >4 publications with Plg and Mammary Gland
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