NP_066296.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,945 Da
NCBI Official Full Name
pregnancy-specific beta-1-glycoprotein 3
NCBI Official Synonym Full Names
pregnancy specific beta-1-glycoprotein 3
NCBI Protein Information
pregnancy-specific beta-1-glycoprotein 3; PSBG-3; PS-beta-G-3; carcinoembryonic antigen SG5; pregnancy-specific glycoprotein 3
UniProt Protein Name
Pregnancy-specific beta-1-glycoprotein 3
UniProt Synonym Protein Names
Carcinoembryonic antigen SG5
UniProt Synonym Gene Names
UniProt Entry Name
PSG3_HUMAN
NCBI Summary for PSG3
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
UniProt Comments for PSG3
PSG3: Belongs to the immunoglobulin superfamily. CEA family
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: extracellular region
Biological Process: defense response; female pregnancy
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Products associated with PSG3 elisa kit
Diseases associated with PSG3 elisa kit
Organs/Tissues associated with PSG3 elisa kit
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