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Renin elisa kit :: Rat Renin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS727443
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells-(Competitive)  /  $455 +1 FREE 8GB USB
48-Strip-Wells-(Sandwich)  /  $455 +1 FREE 8GB USB
96-Strip-Wells-(Competitive)  /  $660 +1 FREE 8GB USB
96-Strip-Wells-(Sandwich)  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells-(Competitive)  /  $2,925 +3 FREE 8GB USB
5x96-Strip-Wells-(Sandwich)  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells-(Competitive)  /  $5,490 +6 FREE 8GB USB
10x96-Strip-Wells-(Sandwich)  /  $5,490 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Renin, ELISA Kit

★Popular Item★
 Also Known As   

Rat Renin ELISA Kit

 Product Gene Name   

Renin elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Competitive ELISA Manual Insert    Competitive ELISA PDF Manual
  Sandwich ELISA Manual Insert    Sandwich ELISA PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    613092
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Renin. No significant cross-reactivity or interference between Renin and analogues was observed. NOTE: Limited by current skills and knowledge, it is impossible for us to complete the cross-reactivity detection between Renin and all the analogues, therefore, cross reaction may still exist in some cases.
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive or Sandwich
 Detection Range    50-1000pg/mL
 Sensitivity    1.0pg/ml
 Intended Uses    This Renin ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Rat Renin. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Renin elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Renin purchase    MBS727443 is a ready-to-use microwell, strip plate Competitive or Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Renin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 50-1000pg/mL in biological research samples containing Renin, with an estimated sensitivity of 1.0pg/ml. The ELISA analytical biochemical technique of the MBS727443 kit is based on Renin antibody-Renin antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Renin antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Renin. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for Renin elisa kit

   Principle of the Assay: Renin ELISA kit applies the quantitative sandwich enzyme immunoassay technique. The microtiter plate has been pre-coated with a monoclonal antibody specific for Renin. Standards or samples are then added to the microtiter plate wells and Renin if present, will bind to the antibody pre-coated wells. In order to quantitatively determine the amount of Renin present in the sample, a standardized preparation of horseradish peroxidase (HRP)-conjugated polyclonal antibody, specific for Renin are added to each well to "sandwich" the Renin immobilized on the plate. The microtiter plate undergoes incubation, and then the wells are thoroughly washed to remove all unbound components. Next, substrate solutions are added to each well. The enzyme (HRP) and substrate are allowed to react over a short incubation period. Only those wells that contain Renin and enzyme-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The Renin concentration in each sample is interpolated from this standard curve.
 Product Categories/Family for Renin elisa kit    Cardiovascular
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 Typical Testing Data/Standard Curve (for reference only) of Renin elisa kit    Renin elisa kit Typical Testing Data/Standard Curve (for reference only) image
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NCBI/Uniprot data below describe general gene information for Renin. It may not necessarily be applicable to this product.
 NCBI GI #    190994
 NCBI GeneID    5972
 NCBI Accession #    AAA60363.1 [Other Products]
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 UniProt Secondary Accession #    Q6FI38; Q6T5C2 [Other Products]
 UniProt Related Accession #    P00797 [Other Products]
 Molecular Weight    44,726 Da
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 NCBI Official Full Name    renin
 NCBI Official Synonym Full Names    renin
 NCBI Official Symbol    REN [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    renin; angiotensinogenase; renin precursor, renal; angiotensin-forming enzyme
 UniProt Protein Name    Renin
 UniProt Synonym Protein Names   
 Protein Family    Renin
 UniProt Gene Name    REN [Similar Products]
 UniProt Entry Name    RENI_HUMAN
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 NCBI Summary for Renin    Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
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 UniProt Comments for Renin    REN: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Interacts with ATP6AP2. Interaction with ATP6AP2 results in a 5-fold increased efficiency in angiotensinogen processing. Belongs to the peptidase A1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; EC; Protease; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: extracellular space; cytoplasm; plasma membrane; extracellular region

Molecular Function: peptidase activity; insulin-like growth factor receptor binding; aspartic-type endopeptidase activity; receptor binding

Biological Process: response to cAMP; hormone-mediated signaling; drinking behavior; cell maturation; renin-angiotensin regulation of aldosterone production; male gonad development; response to lipopolysaccharide; angiotensin maturation; proteolysis; cellular protein metabolic process; regulation of blood pressure; beta-amyloid metabolic process; regulation of MAPKKK cascade; mesonephros development; kidney development

Disease: Renal Tubular Dysgenesis; Hyperuricemic Nephropathy, Familial Juvenile, 2
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 Research Articles on Renin    1. Data suggest that the renin-angiotensin system plays a critical role in placentation and nephrogenesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Renin elisa kitPathways associated with Renin elisa kit
 Reference Product  PubMed Publications
 ACE elisa kit  >143 publications with Renin and ACE
 PTGS2 elisa kit  >74 publications with Renin and PTGS2
 AGT elisa kit  >56 publications with Renin and AGT
 INS elisa kit  >31 publications with Renin and INS
 NOS3 elisa kit  >23 publications with Renin and NOS3
 ATP6AP2 elisa kit  >4 publications with Renin and ATP6AP2
 RENBP elisa kit  >2 publications with Renin and RENBP
 DIF elisa kit  >1 publications with Renin and DIF
 EDN1 elisa kit  >1 publications with Renin and EDN1
 KNG1 elisa kit  >1 publications with Renin and KNG1
 Products by Pathway  Pathway Diagram
 ACE Inhibitor Pathway antibodies  ACE Inhibitor Pathway Diagram
 Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies  Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
 Renin-angiotensin System Pathway antibodies  Renin-angiotensin System Pathway Diagram
Diseases associated with Renin elisa kitOrgans/Tissues associated with Renin elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >4277 publications with Renin and Kidney Diseases
 Renal Insufficiency Antibodies  >2902 publications with Renin and Renal Insufficiency
 Hypertension Antibodies  >1210 publications with Renin and Hypertension
 Heart Diseases Antibodies  >1093 publications with Renin and Heart Diseases
 Necrosis Antibodies  >888 publications with Renin and Necrosis
 Acute Kidney Injury Antibodies  >874 publications with Renin and Acute Kidney Injury
 Hypertension, Renal Antibodies  >613 publications with Renin and Hypertension, Renal
 Ischemia Antibodies  >596 publications with Renin and Ischemia
 Proteinuria Antibodies  >498 publications with Renin and Proteinuria
 Myocardial Ischemia Antibodies  >497 publications with Renin and Myocardial Ischemia
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >5456 publications with Renin and Kidney
 Lung Antibodies  >1047 publications with Renin and Lung
 Skin Antibodies  >515 publications with Renin and Skin
 Intestine Antibodies  >340 publications with Renin and Intestine
 Embryonic Tissue Antibodies  >227 publications with Renin and Embryonic Tissue
 Pancreas Antibodies  >139 publications with Renin and Pancreas
 Bladder Antibodies  >138 publications with Renin and Bladder
 Testis Antibodies  >125 publications with Renin and Testis
 Ovary Antibodies  >110 publications with Renin and Ovary
 Placenta Antibodies  >80 publications with Renin and Placenta
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