NP_112393.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,728 Da
NCBI Official Full Name
transforming growth factor beta-2
NCBI Official Synonym Full Names
transforming growth factor, beta 2
NCBI Official Synonym Symbols
NCBI Protein Information
transforming growth factor beta-2; TGF-beta-2; TGF beta 2 protein
UniProt Protein Name
Transforming growth factor beta-2
UniProt Synonym Gene Names
UniProt Entry Name
TGFB2_RAT
NCBI Summary for TGFB2
binds the transforming growth factor-beta receptor; plays a role in regulation of cell growth and proliferation; may be involved in mesenchymal-epithelial cell interactions during development [RGD, Feb 2006]
UniProt Comments for TGFB2
TGFB2: TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. Homodimer; disulfide-linked. Heterodimers with TGFB1 and with TGFB3 have been found in bone. Interacts with the serine proteases, HTRA1 and HTRA3. Interacts with ASPN. Belongs to the TGF-beta family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell development/differentiation; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Cellular Component: axon; basement membrane; cell soma; cell surface; cytoplasm; endosome; extracellular matrix; extracellular region; extracellular space; secretory granule; trans-Golgi network
Molecular Function: beta-amyloid binding; cytokine activity; protein heterodimerization activity; protein homodimerization activity; protein N-terminus binding; punt binding; receptor binding; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta receptor binding
Biological Process: activation of protein kinase activity; aging; axon guidance; blood vessel development; blood vessel remodeling; cardiac muscle cell proliferation; cardioblast differentiation; cartilage condensation; cell cycle arrest; cell death; cell development; cell migration; cell morphogenesis; collagen fibril organization; dopamine biosynthetic process; embryonic gut development; embryonic limb morphogenesis; embryonic neurocranium morphogenesis; epithelial to mesenchymal transition; extracellular matrix organization and biogenesis; eye development; female pregnancy; glial cell migration; gut development; hair follicle development; hair follicle morphogenesis; heart development; heart morphogenesis; hemopoiesis; hindbrain development; inner ear development; intercellular junction assembly and maintenance; kidney development; lung development; male gonad development; negative regulation of apoptosis; negative regulation of cell growth; negative regulation of cell proliferation; negative regulation of epithelial cell proliferation; negative regulation of immune response; negative regulation of Ras protein signal transduction; negative regulation of release of sequestered calcium ion into cytosol; neural tube closure; neuron development; neuron fate commitment; neutrophil chemotaxis; palate development; pancreas development; positive regulation of apoptosis; positive regulation of cardioblast differentiation; positive regulation of catagen; positive regulation of cell adhesion mediated by integrin; positive regulation of cell cycle; positive regulation of cell growth; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of heart contraction; positive regulation of immune response; positive regulation of integrin biosynthetic process; positive regulation of neuron apoptosis; positive regulation of ossification; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein secretion; positive regulation of stress-activated MAPK cascade; protein amino acid phosphorylation; regulation of actin cytoskeleton organization and biogenesis; regulation of apoptosis; regulation of cell growth; regulation of cell proliferation; regulation of MAPKKK cascade; regulation of transforming growth factor-beta2 production; response to cold; response to cytokine stimulus; response to drug; response to estradiol stimulus; response to estrogen stimulus; response to hypoxia; response to organic nitrogen; response to progesterone stimulus; response to radiation; response to retinoic acid; response to vitamin D; response to wounding; salivary gland morphogenesis; skeletal development; skeletal muscle development; SMAD protein nuclear translocation; somatic stem cell division; thyroid gland development; transforming growth factor beta receptor signaling pathway; uterus development; wound healing
Research Articles on TGFB2
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Pathways associated with TGFB2 elisa kit
Diseases associated with TGFB2 elisa kit
Organs/Tissues associated with TGFB2 elisa kit
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