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TGF-beta3 elisa kit :: Rat TGF-beta3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2515124
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TGF-beta3, ELISA Kit

★Popular Item★
 Also Known As   

Rat TGF-beta3 (Transforming Growth Factor Beta 3) ELISA Kit

 Product Gene Name   

TGF-beta3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    107970
 3D Structure    ModBase 3D Structure for P10600
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 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Rat TGF-beta3. No significant cross-reactivity or interference between Rat TGF-beta3 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Rat TGF-beta3 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    15.625--1000pg/mL
 Sensitivity    9.375pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TGF-beta3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TGF-beta3 purchase    MBS2515124 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the TGF-beta3, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.625--1000pg/mL in biological research samples containing TGF-beta3, with an estimated sensitivity of 9.375pg/mL. The ELISA analytical biochemical technique of the MBS2515124 kit is based on TGF-beta3 antibody-TGF-beta3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TGF-beta3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TGF-beta3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TGF-beta3 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of TGF-beta3 in Rat serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat TGF-beta3. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Rat TGF-beta3 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat TGF-beta3, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Rat TGF-beta3. You can calculate the concentration of Rat TGF-beta3 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of TGF-beta3 elisa kit    TGF-beta3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2515124. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TGF-beta3. It may not necessarily be applicable to this product.
 NCBI GI #    4507465
 NCBI GeneID    7043
 NCBI Accession #    NP_003230.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003239.3 [Other Products]
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 UniProt Primary Accession #    P10600 [Other Products]
 UniProt Secondary Accession #    Q8WV88 [Other Products]
 UniProt Related Accession #    P10600 [Other Products]
 Molecular Weight    35,708 Da
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 NCBI Official Full Name    transforming growth factor beta-3 preproprotein
 NCBI Official Synonym Full Names    transforming growth factor, beta 3
 NCBI Official Symbol    TGFB3 [Similar Products]
 NCBI Official Synonym Symbols   
ARVD; RNHF; ARVD1; TGF-beta3
[Similar Products]
 NCBI Protein Information    transforming growth factor beta-3; TGF-beta-3; prepro-transforming growth factor beta-3
 UniProt Protein Name    Transforming growth factor beta-3
 UniProt Gene Name    TGFB3 [Similar Products]
 UniProt Synonym Gene Names    TGF-beta-3; LAP [Similar Products]
 UniProt Entry Name    TGFB3_HUMAN
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 NCBI Summary for TGF-beta3    This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and is involved in embryogenesis and cell differentiation. Defects in this gene are a cause of familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Mar 2009]
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 UniProt Comments for TGF-beta3    TGFB3: Involved in embryogenesis and cell differentiation. Homodimer; disulfide-linked. Interacts with ASPN. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted; Ligand, receptor tyrosine kinase; Motility/polarity/chemotaxis; Cell development/differentiation

Chromosomal Location of Human Ortholog: 14q24

Cellular Component: extracellular matrix; extracellular space; cell surface; cell soma; T-tubule; extracellular region; plasma membrane; nucleus

Molecular Function: identical protein binding; protein binding; growth factor activity; protein heterodimerization activity; transforming growth factor beta binding; punt binding; cytokine activity

Biological Process: extracellular matrix organization and biogenesis; positive regulation of apoptosis; activation of MAPK activity; positive regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; female pregnancy; palate development; SMAD protein nuclear translocation; regulation of apoptosis; odontogenesis; negative regulation of cell proliferation; platelet degranulation; mammary gland development; transforming growth factor beta receptor signaling pathway; salivary gland morphogenesis; embryonic neurocranium morphogenesis; negative regulation of neuron apoptosis; cell growth; inner ear development; aging; positive regulation of filopodium formation; uterine wall breakdown; platelet activation; intercellular junction assembly and maintenance; in utero embryonic development; positive regulation of bone mineralization; regulation of cell proliferation; gut development; positive regulation of protein secretion; response to estrogen stimulus; negative regulation of DNA replication; positive regulation of cell division; regulation of MAPKKK cascade; response to hypoxia; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; response to progesterone stimulus; negative regulation of transforming growth factor beta receptor signaling pathway; alveolus development; positive regulation of DNA replication

Disease: Arrhythmogenic Right Ventricular Dysplasia, Familial, 1; Rienhoff Syndrome
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 Research Articles on TGF-beta3    1. We identified genetic variants in TGFB3 and ARHGAP29 associated with suboptimal healing outcome.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TGF-beta3 elisa kitPathways associated with TGF-beta3 elisa kit
 Reference Product  PubMed Publications
 TGFB2 elisa kit  >572 publications with TGF-beta3 and TGFB2
 EGF elisa kit  >22 publications with TGF-beta3 and EGF
 SERPINE1 elisa kit  >16 publications with TGF-beta3 and SERPINE1
 TGFBR2 elisa kit  >10 publications with TGF-beta3 and TGFBR2
 TGFBR1 elisa kit  >9 publications with TGF-beta3 and TGFBR1
 SMAD5 elisa kit  >2 publications with TGF-beta3 and SMAD5
 FN1 elisa kit  >2 publications with TGF-beta3 and FN1
 TIMP1 elisa kit  >1 publications with TGF-beta3 and TIMP1
 ACVRL1 elisa kit  >1 publications with TGF-beta3 and ACVRL1
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 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chronic Myeloid Leukemia Pathway antibodies  Chronic Myeloid Leukemia Pathway Diagram
 Chronic Myeloid Leukemia Pathway antibodies  Chronic Myeloid Leukemia Pathway Diagram
 Colorectal Cancer Pathway antibodies  Colorectal Cancer Pathway Diagram
Diseases associated with TGF-beta3 elisa kitOrgans/Tissues associated with TGF-beta3 elisa kit
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >191 publications with TGF-beta3 and Fibrosis
 Cleft Palate Antibodies  >108 publications with TGF-beta3 and Cleft Palate
 Disease Models, Animal Antibodies  >105 publications with TGF-beta3 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >88 publications with TGF-beta3 and Cardiovascular Diseases
 Inflammation Antibodies  >81 publications with TGF-beta3 and Inflammation
 Necrosis Antibodies  >65 publications with TGF-beta3 and Necrosis
 Heart Diseases Antibodies  >54 publications with TGF-beta3 and Heart Diseases
 Breast Neoplasms Antibodies  >40 publications with TGF-beta3 and Breast Neoplasms
 Lung Diseases Antibodies  >39 publications with TGF-beta3 and Lung Diseases
 Hypertrophy Antibodies  >39 publications with TGF-beta3 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >362 publications with TGF-beta3 and Bone
 Connective Tissue Antibodies  >252 publications with TGF-beta3 and Connective Tissue
 Embryonic Tissue Antibodies  >145 publications with TGF-beta3 and Embryonic Tissue
 Bone Marrow Antibodies  >130 publications with TGF-beta3 and Bone Marrow
 Mouth Antibodies  >121 publications with TGF-beta3 and Mouth
 Heart Antibodies  >81 publications with TGF-beta3 and Heart
 Lung Antibodies  >79 publications with TGF-beta3 and Lung
 Eye Antibodies  >68 publications with TGF-beta3 and Eye
 Brain Antibodies  >67 publications with TGF-beta3 and Brain
 Liver Antibodies  >52 publications with TGF-beta3 and Liver
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