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TR elisa kit :: Rat TR ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2510150
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Rat TR (Thrombin Receptor) ELISA Kit

 Product Gene Name   

TR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q99376
 Species Reactivity    Rat
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 Specificity    This kit recognizes natural and recombinant Rat TR. No significant cross-reactivity or interference between Rat TR and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    1.563-100ng/mL
 Sensitivity    Min: 0.938ng/mL; Max: 100ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TR purchase    MBS2510150 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the TR, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.563-100ng/mL in biological research samples containing TR, with an estimated sensitivity of Min: 0.938ng/mL; Max: 100ng/mL. The ELISA analytical biochemical technique of the MBS2510150 kit is based on TR antibody-TR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TR elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Rat TR concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to TR. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for TR and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain TR, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of TR. You can calculate the concentration of TR in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of TR elisa kit    TR elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2510150. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TR. It may not necessarily be applicable to this product.
 NCBI GI #    281306746
 NCBI GeneID    64678
 NCBI Accession #    NP_073203.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_022712.1 [Other Products]
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 UniProt Primary Accession #    Q99376 [Other Products]
 UniProt Related Accession #    Q99376 [Other Products]
 Molecular Weight    70,153 Da
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 NCBI Official Full Name    transferrin receptor protein 1
 NCBI Official Synonym Full Names    transferrin receptor
 NCBI Official Symbol    Tfrc [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    transferrin receptor protein 1; TR; tfR; tfR1
 UniProt Protein Name    Transferrin receptor protein 1
 UniProt Synonym Protein Names   
CD_antigen: CD71
 Protein Family    tRNA
 UniProt Gene Name    Tfrc [Similar Products]
 UniProt Synonym Gene Names    Trfr; TR; TfR; TfR1; Trfr [Similar Products]
 UniProt Entry Name    TFR1_RAT
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 NCBI Summary for TR    receptor for transferrin; involved in regulating stellate cell activation [RGD, Feb 2006]
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 UniProt Comments for TR    TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.

Protein type: Membrane protein, integral; Receptor, misc.; Cell surface

Cellular Component: extracellular space; cell surface; mitochondrion; intracellular membrane-bound organelle; recycling endosome membrane; cell; cytoplasmic membrane-bound vesicle; integral to membrane; extracellular region; coated pit; recycling endosome; perinuclear region of cytoplasm; plasma membrane; melanosome; endosome; vesicle; external side of plasma membrane

Molecular Function: identical protein binding; transferrin receptor activity; chaperone binding; double-stranded RNA binding; Hsp70 protein binding

Biological Process: receptor-mediated endocytosis; response to retinoic acid; response to inorganic substance; cellular iron ion homeostasis; transferrin transport; osteoclast differentiation; regulation of cell proliferation; response to manganese ion; response to organic substance; response to copper ion; response to hypoxia; acute-phase response; positive regulation of bone resorption; regulation of cell growth; response to iron ion; response to nutrient; aging
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 Research Articles on TR    1. Whole-genome profiling reveals that increasing dietary protein from 5 to 40% increass duodenal transcript expression of divalent metal transporter 1 (DMT1) 3.2-fold, duodenal cytochrome b (Dcytb) 1.8-fold, and transferrin receptor (TfR) 1.8-fold.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TR elisa kitOrgans/Tissues associated with TR elisa kit
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Iron Uptake And Transport Pathway antibodies  Iron Uptake And Transport Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >28 publications with TR and Liver
 Brain Antibodies  >25 publications with TR and Brain
 Lung Antibodies  >14 publications with TR and Lung
 Kidney Antibodies  >10 publications with TR and Kidney
 Heart Antibodies  >6 publications with TR and Heart
 Prostate Antibodies  >6 publications with TR and Prostate
 Colon Antibodies  >4 publications with TR and Colon
 Small Intestine Antibodies  >4 publications with TR and Small Intestine
 Adipose Tissue Antibodies  >3 publications with TR and Adipose Tissue
 Eye Antibodies  >3 publications with TR and Eye
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