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T3 elisa kit :: Rat Triiodothyronine ELISA Kit

Scan QR to view Datasheet Catalog #    MBS016153
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Triiodothyronine (T3), ELISA Kit

 Also Known As   

Rat Triiodothyronine ELISA Kit

 Product Gene Name   

T3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    190120
 3D Structure    ModBase 3D Structure for P10827
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 Species Reactivity    Rat
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Sandwich
 Detection Range    0.25 nmol/L - 8 nmol/L.
 Sensitivity    0.1 nmol/L.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of T3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for T3 purchase    MBS016153 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Triiodothyronine (T3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.25 nmol/L - 8 nmol/L in biological research samples containing T3, with an estimated sensitivity of 0.1 nmol/L. The ELISA analytical biochemical technique of the MBS016153 kit is based on T3 antibody-T3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect T3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, T3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for T3 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of T3 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
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 Typical Testing Data/Standard Curve (for reference only) of T3 elisa kit    T3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS016153. Click to request current manual
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NCBI/Uniprot data below describe general gene information for T3. It may not necessarily be applicable to this product.
 NCBI GI #    300116309
 NCBI GeneID    7067
 NCBI Accession #    NP_001177848.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001190919.1 [Other Products]
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 UniProt Primary Accession #    P10827 [Other Products]
 UniProt Secondary Accession #    P21205; Q8N6A1; Q96H73; A8K3B5 [Other Products]
 UniProt Related Accession #    P10827 [Other Products]
 Molecular Weight    54,816 Da
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 NCBI Official Full Name    thyroid hormone receptor alpha isoform 2
 NCBI Official Synonym Full Names    thyroid hormone receptor, alpha
 NCBI Official Symbol    THRA [Similar Products]
 NCBI Official Synonym Symbols   
AR7; EAR7; ERBA; CHNG6; ERBA1; NR1A1; THRA1; THRA2; ERB-T-1; c-ERBA-1
[Similar Products]
 NCBI Protein Information    thyroid hormone receptor alpha; EAR-7; c-erbA-alpha; ERBA-related 7; V-erbA-related protein 7; triiodothyronine receptor; nuclear receptor subfamily 1 group A member 1; thyroid normone nuclear receptor alpha variant 1; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
 UniProt Protein Name    Thyroid hormone receptor alpha
 UniProt Synonym Protein Names   
Nuclear receptor subfamily 1 group A member 1; V-erbA-related protein 7; EAR-7; c-erbA-1; c-erbA-alpha
 UniProt Gene Name    THRA [Similar Products]
 UniProt Synonym Gene Names    EAR7; ERBA1; NR1A1; THRA1; THRA2; EAR-7 [Similar Products]
 UniProt Entry Name    THA_HUMAN
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 NCBI Summary for T3    The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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 UniProt Comments for T3    TR-alpha: nuclear hormone receptor and transcription factor. High affinity receptor for triiodothyronine. Interacts with SRC-3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Four splice variant isoforms have been described.

Protein type: DNA-binding; Transcription factor; Nuclear receptor

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: nucleoplasm; nucleus; cytosol

Molecular Function: protein domain specific binding; protein binding; zinc ion binding; chromatin DNA binding; TATA-binding protein binding; sequence-specific DNA binding; protein complex binding; steroid hormone receptor activity; thyroid hormone receptor activity; transcription factor binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcriptional preinitiation complex assembly; transcription initiation from RNA polymerase II promoter; ossification; cytoplasmic sequestering of transcription factor; intracellular receptor-mediated signaling pathway; hormone-mediated signaling; positive regulation of female receptivity; regulation of myeloid cell apoptosis; regulation of heart contraction; regulation of lipid catabolic process; regulation of transcription from RNA polymerase II promoter; female courtship behavior; learning and/or memory; thyroid gland development; erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; gene expression; steroid hormone mediated signaling; response to cold; negative regulation of transcription, DNA-dependent; cartilage condensation

Disease: Hypothyroidism, Congenital, Nongoitrous, 6
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 Research Articles on T3    1. THRA gene polymorphisms are associated with obesity development. This is a novel observation linking the THRA locus to metabolic phenotypes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with T3 elisa kitPathways associated with T3 elisa kit
 Reference Product  PubMed Publications
 NCOR1 elisa kit  >2 publications with T3 and NCOR1
 MED1 elisa kit  >2 publications with T3 and MED1
 RXRG elisa kit  >1 publications with T3 and RXRG
 ESR1 elisa kit  >1 publications with T3 and ESR1
 RXRA elisa kit  >1 publications with T3 and RXRA
 Products by Pathway  Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram
 Nuclear Receptors Pathway antibodies  Nuclear Receptors Pathway Diagram
 Thyroid Hormone Signaling Pathway antibodies  Thyroid Hormone Signaling Pathway Diagram
Diseases associated with T3 elisa kitOrgans/Tissues associated with T3 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >27 publications with T3 and Neoplasms
 Cardiovascular Diseases Antibodies  >19 publications with T3 and Cardiovascular Diseases
 Thyroid Diseases Antibodies  >19 publications with T3 and Thyroid Diseases
 Nervous System Diseases Antibodies  >4 publications with T3 and Nervous System Diseases
 Kidney Diseases Antibodies  >3 publications with T3 and Kidney Diseases
 Brain Diseases Antibodies  >3 publications with T3 and Brain Diseases
 Liver Diseases Antibodies  >3 publications with T3 and Liver Diseases
 Necrosis Antibodies  >3 publications with T3 and Necrosis
 Fatty Liver Antibodies  >2 publications with T3 and Fatty Liver
 Weight Loss Antibodies  >2 publications with T3 and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >60 publications with T3 and Thyroid
 Blood Antibodies  >26 publications with T3 and Blood
 Bone Antibodies  >18 publications with T3 and Bone
 Brain Antibodies  >14 publications with T3 and Brain
 Liver Antibodies  >13 publications with T3 and Liver
 Muscle Antibodies  >6 publications with T3 and Muscle
 Heart Antibodies  >6 publications with T3 and Heart
 Kidney Antibodies  >5 publications with T3 and Kidney
 Ear Antibodies  >4 publications with T3 and Ear
 Eye Antibodies  >4 publications with T3 and Eye
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