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Tnfrsf11b elisa kit :: Rat Tumor necrosis factor receptor superfamily member 11B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS288817
 Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $325 +1 FREE 8GB USB
96-Strip-Wells  /  $435 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,290 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tumor necrosis factor receptor superfamily member 11B (Tnfrsf11b), ELISA Kit

★Popular Item★
 Also Known As   

Rat Tumor necrosis factor receptor superfamily member 11B ELISA Kit

 Product Synonym Names    Tumor necrosis factor receptor superfamily member 11B; Osteoprotegerin; Tnfrsf11b; Opg
 Product Gene Name   

Tnfrsf11b elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS288817 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for O08727
 Species Reactivity    Rat
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 Specificity    Recombinant and natural Rat Tumor necrosis factor receptor superfamily member 11B
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 Samples    Serum, plasma, tissue homogenates, cell culture supernates or other biological fluids
 Detection Range    15.6-1000 pg/mL
 Intra-assay Precision    Intra-Assay CV: <=4.8%
 Inter-assay Precision    Inter-Assay CV: <=7.7%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Tnfrsf11b elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Tnfrsf11b purchase    MBS288817 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tumor necrosis factor receptor superfamily member 11B (Tnfrsf11b) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6-1000 pg/mL in biological research samples containing Tnfrsf11b. The ELISA analytical biochemical technique of the MBS288817 kit is based on Tnfrsf11b antibody-Tnfrsf11b antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Tnfrsf11b antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Tnfrsf11b. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell culture supernates or other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for Tnfrsf11b elisa kit

   Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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  Typical Testing Data/Standard Curve (for reference only) of Tnfrsf11b elisa kit    Tnfrsf11b elisa kit  Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS288817. Click to request current manual
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NCBI/Uniprot data below describe general gene information for Tnfrsf11b. It may not necessarily be applicable to this product.
 NCBI GI #    6981306
 NCBI GeneID    25341
 NCBI Accession #    NP_037002.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012870.2 [Other Products]
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 UniProt Primary Accession #    O08727 [Other Products]
 UniProt Related Accession #    O08727 [Other Products]
 Molecular Weight    46,192 Da
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 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 11B
 NCBI Official Synonym Full Names    tumor necrosis factor receptor superfamily, member 11b
 NCBI Official Symbol    Tnfrsf11b [Similar Products]
 NCBI Official Synonym Symbols   
Opg
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 11B
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 11B
 UniProt Synonym Protein Names   
Osteoprotegerin
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    Tnfrsf11b [Similar Products]
 UniProt Synonym Gene Names    Opg [Similar Products]
 UniProt Entry Name    TR11B_RAT
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 NCBI Summary for Tnfrsf11b    plays a role in the negative regulation of bone resorption by inhibiting formation of osteoclasts [RGD, Feb 2006]
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 UniProt Comments for Tnfrsf11b    Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis ().
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 Research Articles on Tnfrsf11b    1. RANKL and OPG expressions were not changed by chronic exposure to fluoride in the drinking water during the studied periods; on the other hand, TRAP expression was changed (at 7 days) by chronic exposure to fluoride
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Tnfrsf11b elisa kitPathways associated with Tnfrsf11b elisa kit
 Reference Product  PubMed Publications
 Tnfsf11 elisa kit  >880 publications with Tnfrsf11b and Tnfsf11
 Tnfsf10 elisa kit  >53 publications with Tnfrsf11b and Tnfsf10
 Tgfb1 elisa kit  >24 publications with Tnfrsf11b and Tgfb1
 Il18 elisa kit  >5 publications with Tnfrsf11b and Il18
 Osm elisa kit  >4 publications with Tnfrsf11b and Osm
 Igf1r elisa kit  >4 publications with Tnfrsf11b and Igf1r
 Pparg elisa kit  >2 publications with Tnfrsf11b and Pparg
 Il17a elisa kit  >2 publications with Tnfrsf11b and Il17a
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Osteoblast Pathway antibodies  Osteoblast Pathway Diagram
 Osteoclast Pathway antibodies  Osteoclast Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 TNFR2 Non-canonical NF-kB Pathway antibodies  TNFR2 Non-canonical NF-kB Pathway Diagram
 TNFs Bind Their Physiological Receptors Pathway antibodies  TNFs Bind Their Physiological Receptors Pathway Diagram
Diseases associated with Tnfrsf11b elisa kitOrgans/Tissues associated with Tnfrsf11b elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1263 publications with Tnfrsf11b and Necrosis
 Bone Resorption Antibodies  >716 publications with Tnfrsf11b and Bone Resorption
 Osteoporosis Antibodies  >341 publications with Tnfrsf11b and Osteoporosis
 Cardiovascular Diseases Antibodies  >246 publications with Tnfrsf11b and Cardiovascular Diseases
 Inflammation Antibodies  >183 publications with Tnfrsf11b and Inflammation
 Osteolysis Antibodies  >113 publications with Tnfrsf11b and Osteolysis
 Arthritis, Rheumatoid Antibodies  >109 publications with Tnfrsf11b and Arthritis, Rheumatoid
 Kidney Diseases Antibodies  >63 publications with Tnfrsf11b and Kidney Diseases
 Breast Neoplasms Antibodies  >44 publications with Tnfrsf11b and Breast Neoplasms
 Pain Antibodies  >43 publications with Tnfrsf11b and Pain
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >283 publications with Tnfrsf11b and Connective Tissue
 Prostate Antibodies  >46 publications with Tnfrsf11b and Prostate
 Lung Antibodies  >20 publications with Tnfrsf11b and Lung
 Eye Antibodies  >14 publications with Tnfrsf11b and Eye
 Inner Ear Antibodies  >8 publications with Tnfrsf11b and Inner Ear
 Colon Antibodies  >7 publications with Tnfrsf11b and Colon
 Pancreas Antibodies  >4 publications with Tnfrsf11b and Pancreas
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