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UK elisa kit :: Rat Urokinase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS034751 UK elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Urokinase (UK), ELISA Kit

 Also Known As   

Rat Urokinase ELISA Kit

 Product Gene Name   

UK elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    173391
 3D Structure    ModBase 3D Structure for Q03405
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 Species Reactivity    Rat
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of UK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for UK purchase    MBS034751 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Urokinase (UK) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing UK. The ELISA analytical biochemical technique of the MBS034751 kit is based on UK antibody-UK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect UK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, UK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for UK. It may not necessarily be applicable to this product.
 NCBI GI #    4505865
 NCBI GeneID    5329
 NCBI Accession #    NP_002650.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002659.3 [Other Products]
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 UniProt Primary Accession #    Q03405 [Other Products]
 UniProt Secondary Accession #    Q12876; Q15845; Q16887; Q6IB52; Q9BWT0; Q9NYC8; Q9UD69; Q9UEA6; Q9UM92; Q9UMV0; A8K409 [Other Products]
 UniProt Related Accession #    Q03405 [Other Products]
 Molecular Weight    36,978 Da
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 NCBI Official Full Name    urokinase plasminogen activator surface receptor isoform 1
 NCBI Official Synonym Full Names    plasminogen activator, urokinase receptor
 NCBI Official Symbol    PLAUR [Similar Products]
 NCBI Official Synonym Symbols   
CD87; UPAR; URKR; U-PAR
[Similar Products]
 NCBI Protein Information    urokinase plasminogen activator surface receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; urokinase-type plasminogen activator (uPA) receptor
 UniProt Protein Name    Urokinase plasminogen activator surface receptor
 UniProt Synonym Protein Names   
Monocyte activation antigen Mo3
 Protein Family    Urokinase-type plasminogen activator
 UniProt Gene Name    PLAUR [Similar Products]
 UniProt Synonym Gene Names    MO3; UPAR; U-PAR; uPAR [Similar Products]
 UniProt Entry Name    UPAR_HUMAN
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 NCBI Summary for UK    This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for UK    uPAR: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2. Expressed in neurons of the rolandic area of the brain. Expressed in the brain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Receptor, misc.; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: endoplasmic reticulum membrane; extrinsic to membrane; focal adhesion; integral to plasma membrane; endoplasmic reticulum lumen; plasma membrane; integral to membrane

Molecular Function: protein domain specific binding; protein binding; U-plasminogen activator receptor activity; enzyme binding; receptor activity; receptor binding

Biological Process: fibrinolysis; cellular protein metabolic process; regulation of proteolysis; attachment of GPI anchor to protein; C-terminal protein lipidation; signal transduction; cell motility; blood coagulation; post-translational protein modification; chemotaxis
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 Research Articles on UK    1. HIV-1 infected lymphoid organs upregulate expression and release of the cleaved form of uPAR that modulates chemotaxis and virus expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with UK elisa kitDiseases associated with UK elisa kit
 Products by Pathway  Pathway Diagram
 Arf6 Downstream Pathway antibodies  Arf6 Downstream Pathway Diagram
 Attachment Of GPI Anchor To UPAR Pathway antibodies  Attachment Of GPI Anchor To UPAR Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Dissolution Of Fibrin Clot Pathway antibodies  Dissolution Of Fibrin Clot Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies  Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >816 publications with UK and Neoplasms
 Carcinoma Antibodies  >313 publications with UK and Carcinoma
 Neoplasm Invasiveness Antibodies  >261 publications with UK and Neoplasm Invasiveness
 Neoplasm Metastasis Antibodies  >239 publications with UK and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >164 publications with UK and Breast Neoplasms
 Inflammation Antibodies  >111 publications with UK and Inflammation
 Lung Diseases Antibodies  >90 publications with UK and Lung Diseases
 Nervous System Diseases Antibodies  >83 publications with UK and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >83 publications with UK and Cardiovascular Diseases
 Lung Neoplasms Antibodies  >76 publications with UK and Lung Neoplasms
Organs/Tissues associated with UK elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >504 publications with UK and Blood
 Vascular Antibodies  >301 publications with UK and Vascular
 Lung Antibodies  >147 publications with UK and Lung
 Muscle Antibodies  >98 publications with UK and Muscle
 Brain Antibodies  >86 publications with UK and Brain
 Liver Antibodies  >83 publications with UK and Liver
 Embryonic Tissue Antibodies  >80 publications with UK and Embryonic Tissue
 Bone Antibodies  >80 publications with UK and Bone
 Kidney Antibodies  >75 publications with UK and Kidney
 Prostate Antibodies  >65 publications with UK and Prostate
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