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WIPI2 elisa kit :: Rat WD repeat domain phosphoinositide-interacting protein 2 (WIPI2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7247129 WIPI2 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

WD repeat domain phosphoinositide-interacting protein 2 (WIPI2), ELISA Kit

 Also Known As   

Rat WD repeat domain phosphoinositide-interacting protein 2 (WIPI2) ELISA Kit

 Product Gene Name   

WIPI2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    609225
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 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of WIPI2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for WIPI2 purchase    MBS7247129 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the WD repeat domain phosphoinositide-interacting protein 2 (WIPI2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing WIPI2. The ELISA analytical biochemical technique of the MBS7247129 kit is based on WIPI2 antibody-WIPI2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect WIPI2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, WIPI2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for WIPI2 elisa kit    Cell Biology
NCBI/Uniprot data below describe general gene information for WIPI2. It may not necessarily be applicable to this product.
 NCBI GI #    7661580
 NCBI GeneID    26100
 NCBI Accession #    NP_056425.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_015610.3 [Other Products]
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 UniProt Secondary Accession #    Q5MNZ8; Q6FI96; Q75L50; Q96IE4; Q9Y364; B3KNC2 [Other Products]
 UniProt Related Accession #    Q9Y4P8 [Other Products]
 Molecular Weight    48,249 Da
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 NCBI Official Full Name    WD repeat domain phosphoinositide-interacting protein 2 isoform a
 NCBI Official Synonym Full Names    WD repeat domain, phosphoinositide interacting 2
 NCBI Official Symbol    WIPI2 [Similar Products]
 NCBI Official Synonym Symbols   
Atg21; ATG18B; CGI-50; WIPI-2
[Similar Products]
 NCBI Protein Information    WD repeat domain phosphoinositide-interacting protein 2; WIPI49-like protein 2; WD40 repeat protein interacting with phosphoinositides 2
 UniProt Protein Name    WD repeat domain phosphoinositide-interacting protein 2
 UniProt Synonym Protein Names   
WIPI49-like protein 2
 Protein Family    WD repeat domain phosphoinositide-interacting protein
 UniProt Gene Name    WIPI2 [Similar Products]
 UniProt Synonym Gene Names    CGI-50; WIPI-2 [Similar Products]
 UniProt Entry Name    WIPI2_HUMAN
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 NCBI Summary for WIPI2    WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for WIPI2    WIPI2: Probable early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to PtdIns3P. May bind PtdIns3P. Interacts with TECPR1. Ubiquitously expressed. Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors. Belongs to the WD repeat SVP1 family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Autophagy

Chromosomal Location of Human Ortholog: 7p22.1

Cellular Component: nucleoplasm; extrinsic to membrane; protein complex; pre-autophagosomal structure membrane; cytoplasm; autophagic vacuole; cytosol

Molecular Function: protein binding; phosphatidylinositol 3-phosphate binding

Biological Process: autophagic vacuole fusion; mitochondrion degradation; protein amino acid lipidation; cellular response to nitrogen starvation; autophagic vacuole formation
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 Research Articles on WIPI2    1. A role for WIPI2 in the progression of omegasomes into autophagosomes, is reported.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with WIPI2 elisa kitOrgans/Tissues associated with WIPI2 elisa kit
 Reference Product  PubMed Publications
 ULK1 elisa kit  >4 publications with WIPI2 and ULK1
 ULK2 elisa kit  >1 publications with WIPI2 and ULK2
 ATG9A elisa kit  >1 publications with WIPI2 and ATG9A
 ATG9B elisa kit  >1 publications with WIPI2 and ATG9B
 ATG2A elisa kit  >1 publications with WIPI2 and ATG2A
 Organ/Tissue Name  Pubmed Publications
 Mouth Antibodies  >1 publications with WIPI2 and Mouth
 Embryonic Tissue Antibodies  >1 publications with WIPI2 and Embryonic Tissue
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