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ACADVL elisa kit :: Rat acyl-Coenzyme A dehydrogenase, very long chain ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9328889 ACADVL elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

acyl-Coenzyme A dehydrogenase, very long chain (ACADVL), ELISA Kit

 Also Known As   

Rat Very long-chain specific acyl-CoA dehydrogenase, mitochondrial, ACADVL ELISA Kit

 Product Synonym Names    Rat Very long-chain specific acyl-CoA dehydrogenase; mitochondrial (ACADVL) ELISA kit; ACAD6; LCACD; VLCAD; ; acyl-Coenzyme A dehydrogenase; very long chain
 Product Gene Name   

ACADVL elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P45953
 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ACADVL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ACADVL purchase    MBS9328889 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the acyl-Coenzyme A dehydrogenase, very long chain (ACADVL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ACADVL. The ELISA analytical biochemical technique of the MBS9328889 kit is based on ACADVL antibody-ACADVL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ACADVL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ACADVL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ACADVL. It may not necessarily be applicable to this product.
 NCBI GI #    6978435
 NCBI GeneID    25363
 NCBI Accession #    NP_037023.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012891.2 [Other Products]
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 UniProt Primary Accession #    P45953 [Other Products]
 UniProt Related Accession #    P45953 [Other Products]
 Molecular Weight    70,749 Da
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 NCBI Official Full Name    very long-chain specific acyl-CoA dehydrogenase, mitochondrial
 NCBI Official Synonym Full Names    acyl-CoA dehydrogenase, very long chain
 NCBI Official Symbol    Acadvl [Similar Products]
 NCBI Official Synonym Symbols   
VLCAD
[Similar Products]
 NCBI Protein Information    very long-chain specific acyl-CoA dehydrogenase, mitochondrial; Very long chain Acyl-Coa dehydrogenase; VLCAD very-long-chain acyl-CoA dehydrogenase; acyl-Coenzyme A dehydrogenase, very long chain
 UniProt Protein Name    Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
 Protein Family    Very long-chain specific acyl-CoA dehydrogenase
 UniProt Gene Name    Acadvl [Similar Products]
 UniProt Synonym Gene Names    Vlcad; VLCAD [Similar Products]
 UniProt Entry Name    ACADV_RAT
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 NCBI Summary for ACADVL    catalyzes the beta-oxidation of long-chain fatty acids in mitochondrial fatty acid metabolism [RGD, Feb 2006]
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 UniProt Comments for ACADVL    ACADVL: Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons. Defects in ACADVL are the cause of acyl-CoA dehydrogenase very long chain deficiency (ACADVLD). ACADVLD is an autosomal recessive disease which leads to impaired long-chain fatty acid beta-oxidation. It is clinically heterogeneous, with three major phenotypes: a severe childhood form, with early onset, high mortality, and high incidence of cardiomyopathy; a milder childhood form, with later onset, usually with hypoketotic hypoglycemia as the main presenting feature, low mortality, and rare cardiomyopathy; and an adult form, with isolated skeletal muscle involvement, rhabdomyolysis, and myoglobinuria, usually triggered by exercise or fasting. Belongs to the acyl-CoA dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; Lipid-binding; Mitochondrial; EC 1.3.8.9; Lipid Metabolism - fatty acid

Cellular Component: mitochondrion; mitochondrial inner membrane; cytoplasm; nucleolus; nucleus

Molecular Function: acyl-CoA dehydrogenase activity; FAD binding; acyl-CoA binding; very-long-chain-acyl-CoA dehydrogenase activity; long-chain-acyl-CoA dehydrogenase activity

Biological Process: fatty acid beta-oxidation; epithelial cell differentiation; very-long-chain fatty acid catabolic process; thermoregulation; fatty acid beta-oxidation using acyl-CoA dehydrogenase; negative regulation of fatty acid biosynthetic process; negative regulation of fatty acid oxidation
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 Research Articles on ACADVL    1. Very long chain acyl-CoA dehydrogenase (VLCAD) activity declined 34% during 30 min of myocardial ischemia
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ACADVL elisa kitDiseases associated with ACADVL elisa kit
 Products by Pathway  Pathway Diagram
 Beta Oxidation Meta Pathway antibodies  Beta Oxidation Meta Pathway Diagram
 Beta Oxidation Of Palmitoyl-CoA To Myristoyl-CoA Pathway antibodies  Beta Oxidation Of Palmitoyl-CoA To Myristoyl-CoA Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Beta Oxidation 1 Pathway antibodies  Fatty Acid Beta Oxidation 1 Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Mitochondrial Fatty Acid Beta-Oxidation Pathway antibodies  Mitochondrial Fatty Acid Beta-Oxidation Pathway Diagram
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >11 publications with ACADVL and Fatty Liver
 VLCAD deficiency Antibodies  >7 publications with ACADVL and VLCAD deficiency
 Liver Diseases Antibodies  >4 publications with ACADVL and Liver Diseases
 Mitochondrial Diseases Antibodies  >4 publications with ACADVL and Mitochondrial Diseases
 Neoplasms Antibodies  >3 publications with ACADVL and Neoplasms
 Obesity Antibodies  >2 publications with ACADVL and Obesity
 Hepatomegaly Antibodies  >2 publications with ACADVL and Hepatomegaly
 Neoplasm Metastasis Antibodies  >1 publications with ACADVL and Neoplasm Metastasis
 Carcinoma, Squamous Cell Antibodies  >1 publications with ACADVL and Carcinoma, Squamous Cell
 Glucose Intolerance Antibodies  >1 publications with ACADVL and Glucose Intolerance
Organs/Tissues associated with ACADVL elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >11 publications with ACADVL and Liver
 Brain Antibodies  >6 publications with ACADVL and Brain
 Adipose Tissue Antibodies  >2 publications with ACADVL and Adipose Tissue
 Connective Tissue Antibodies  >2 publications with ACADVL and Connective Tissue
 Heart Antibodies  >2 publications with ACADVL and Heart
 Kidney Antibodies  >2 publications with ACADVL and Kidney
 Placenta Antibodies  >1 publications with ACADVL and Placenta
 Eye Antibodies  >1 publications with ACADVL and Eye
 Embryonic Tissue Antibodies  >1 publications with ACADVL and Embryonic Tissue
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