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AURKB elisa kit :: Rat aurora kinase B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9330024 AURKB elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

aurora kinase B (AURKB), ELISA Kit

 Also Known As   

Rat Serine/threonine-protein kinase 12, AURKB ELISA Kit

 Product Synonym Names    Rat Serine/threonine-protein kinase 12 (AURKB) ELISA kit; AIK2; AIM-1; AIM1; ARK2; AurB; IPL1; STK12; STK5; aurkb-sv1; aurkb-sv2; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora-1; aurora-B; serine/threonine kinase 12; aurora kinase B
 Product Gene Name   

AURKB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for O55099
 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AURKB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AURKB purchase    MBS9330024 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the aurora kinase B (AURKB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AURKB. The ELISA analytical biochemical technique of the MBS9330024 kit is based on AURKB antibody-AURKB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AURKB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AURKB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AURKB. It may not necessarily be applicable to this product.
 NCBI GI #    16758580
 NCBI GeneID    114592
 NCBI Accession #    NP_446201.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_053749.1 [Other Products]
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 UniProt Primary Accession #    O55099 [Other Products]
 UniProt Secondary Accession #    Q4V8N1 [Other Products]
 UniProt Related Accession #    O55099 [Other Products]
 Molecular Weight    39,234 Da
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 NCBI Official Full Name    aurora kinase B
 NCBI Official Synonym Full Names    aurora kinase B
 NCBI Official Symbol    Aurkb [Similar Products]
 NCBI Official Synonym Symbols   
Aim1; ARK-2; STK-1; Stk12
[Similar Products]
 NCBI Protein Information    aurora kinase B; AIM-1; aurora 1; aurora-B; aurora-related kinase 2; serine/threonine kinase 12; aurora/IPL1-related kinase 2; serine/threonine-protein kinase 5; serine/threonine-protein kinase 12; serine/threonine-protein kinase aurora-B; aurora- and Ipl1-like midbody-associated protein 1
 UniProt Protein Name    Aurora kinase B
 UniProt Synonym Protein Names   
Aurora 1; Aurora- and IPL1-like midbody-associated protein 1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B
 Protein Family    Aurora kinase
 UniProt Gene Name    Aurkb [Similar Products]
 UniProt Synonym Gene Names    Aik2; Aim1; Airk2; Ark2; Stk1; Stk12; Stk5; ARK-2; Aurora-related kinase 2 [Similar Products]
 UniProt Entry Name    AURKB_RAT
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 NCBI Summary for AURKB    kinase; involved in proper progression of cytokinesis [RGD, Feb 2006]
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 UniProt Comments for AURKB    AurB: a member of the AUR family of kinases. May be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Expressed during S and G2/M phase and expression is upregulated in cancer cells during M phase. Localized to the midzone of central spindle in late anaphase and concentrated into the midbody in telophase and cytokinesis. Colocalizes with gamma tubulin in the mid-body. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Overexpressed in colorectal and other cancer cell lines and thought to cause aneuploidy via histone phosphorylation.

Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Other group; AUR family

Cellular Component: intercellular bridge; spindle microtubule; cytoplasm; spindle; midbody; spindle midzone; spindle pole centrosome; nucleus; condensed nuclear chromosome, pericentric region; chromocenter

Molecular Function: protein serine/threonine kinase activity; metal ion binding; protein serine/threonine/tyrosine kinase activity; histone serine kinase activity; ATP binding; protein kinase activity

Biological Process: positive regulation of cytokinesis; spindle stabilization; cell proliferation; mitotic spindle organization and biogenesis; spindle midzone assembly involved in mitosis; abscission; negative regulation of transcription from RNA polymerase II promoter; negative regulation of protein binding; regulation of cytokinesis; protein amino acid phosphorylation; negative regulation of cytokinesis; negative regulation of B cell apoptosis; aging
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 Research Articles on AURKB    1. RanGTP is crucial in the maintenance of stable kinetochore-microtubule attachments by regulating Aurora B kinase.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AURKB elisa kitDiseases associated with AURKB elisa kit
 Products by Pathway  Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram
 Mitotic M-M/G1 Phases Pathway antibodies  Mitotic M-M/G1 Phases Pathway Diagram
 Mitotic Prometaphase Pathway antibodies  Mitotic Prometaphase Pathway Diagram
 Regulation Of Mitotic Cell Cycle Pathway antibodies  Regulation Of Mitotic Cell Cycle Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >29 publications with AURKB and Neoplasms
 Carcinoma Antibodies  >9 publications with AURKB and Carcinoma
 Brain Diseases Antibodies  >4 publications with AURKB and Brain Diseases
 Leukemia Antibodies  >4 publications with AURKB and Leukemia
 Nervous System Diseases Antibodies  >4 publications with AURKB and Nervous System Diseases
 Drug Toxicity Antibodies  >4 publications with AURKB and Drug Toxicity
 Lung Neoplasms Antibodies  >3 publications with AURKB and Lung Neoplasms
 Breast Neoplasms Antibodies  >3 publications with AURKB and Breast Neoplasms
 Leukemia, Myeloid, Acute Antibodies  >3 publications with AURKB and Leukemia, Myeloid, Acute
 Prostatic Diseases Antibodies  >3 publications with AURKB and Prostatic Diseases
Organs/Tissues associated with AURKB elisa kit
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >4 publications with AURKB and Prostate
 Lung Antibodies  >4 publications with AURKB and Lung
 Liver Antibodies  >3 publications with AURKB and Liver
 Testis Antibodies  >1 publications with AURKB and Testis
 Ovary Antibodies  >1 publications with AURKB and Ovary
 Embryonic Tissue Antibodies  >1 publications with AURKB and Embryonic Tissue
 Connective Tissue Antibodies  >1 publications with AURKB and Connective Tissue
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