NP_683513.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,375 Da
NCBI Official Full Name
C-C motif chemokine 28
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 28
NCBI Protein Information
C-C motif chemokine 28; CC chemokine CCL28; small inducible cytokine A28; small-inducible cytokine A28; mucosae-associated epithelial chemokine; chemokine (C-C motif) ligand 28 splice variant chi; small inducible cytokine subfamily A (Cys-Cys), member 28
UniProt Protein Name
C-C motif chemokine 28
UniProt Synonym Protein Names
Mucosae-associated epithelial chemokine; MEC; Protein CCK1; Small-inducible cytokine A28
UniProt Synonym Gene Names
UniProt Entry Name
CCL28_HUMAN
NCBI Summary for CCL28
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. [provided by RefSeq, Jul 2008]
UniProt Comments for CCL28
CCL28: Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Secreted; Chemokine; Secreted, signal peptide; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5p12
Cellular Component: extracellular space; extracellular region
Molecular Function: chemokine activity
Biological Process: elevation of cytosolic calcium ion concentration; immune response; positive regulation of cell-matrix adhesion; chemotaxis; response to nutrient
Research Articles on CCL28
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Products associated with CCL28 elisa kit
Pathways associated with CCL28 elisa kit
Diseases associated with CCL28 elisa kit
Organs/Tissues associated with CCL28 elisa kit
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