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DISC1 elisa kit :: Rat disrupted in schizophrenia 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9330483 DISC1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

disrupted in schizophrenia 1 (DISC1), ELISA Kit

 Also Known As   

Rat Disrupted in schizophrenia 1 protein, DISC1 ELISA Kit

 Product Synonym Names    Rat Disrupted in schizophrenia 1 protein (DISC1) ELISA kit; RP4-730B13.1; C1orf136; FLJ13381; FLJ21640; FLJ25311; FLJ41105; KIAA0457; SCZD9; ; disrupted in schizophrenia 1
 Product Gene Name   

DISC1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q810H6
 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DISC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DISC1 purchase    MBS9330483 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the disrupted in schizophrenia 1 (DISC1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DISC1. The ELISA analytical biochemical technique of the MBS9330483 kit is based on DISC1 antibody-DISC1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DISC1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DISC1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for DISC1. It may not necessarily be applicable to this product.
 NCBI GI #    30842815
 NCBI GeneID    307940
 NCBI Accession #    NP_783186.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_175596.2 [Other Products]
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 UniProt Primary Accession #    Q810H6 [Other Products]
 UniProt Related Accession #    Q810H6 [Other Products]
 Molecular Weight    92,563 Da
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 NCBI Official Full Name    disrupted in schizophrenia 1 homolog
 NCBI Official Synonym Full Names    disrupted in schizophrenia 1
 NCBI Official Symbol    Disc1 [Similar Products]
 NCBI Protein Information    disrupted in schizophrenia 1 homolog
 UniProt Protein Name    Disrupted in schizophrenia 1 homolog
 Protein Family    Disrupted in schizophrenia
 UniProt Gene Name    Disc1 [Similar Products]
 UniProt Entry Name    DISC1_RAT
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 NCBI Summary for DISC1    interacts with a variety of cytoskeletal proteins; truncated mutant form is associated with Schizophrenia [RGD, Feb 2006]
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 UniProt Comments for DISC1    Function: Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtubule network formation.1 PublicationManual assertion based on experiment in:Ref.3
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 Research Articles on DISC1    1. Knocking down Disc1 in rat prefrontal cortex reduced the threshold for stress-induced cognitive dysfunction, possibly through disinhibited cAMP signaling at neuronal network synapses.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with DISC1 elisa kit
 Disease Name  Pubmed Publications
 Schizophrenia Antibodies  >361 publications with DISC1 and Schizophrenia
 Syndrome Antibodies  >21 publications with DISC1 and Syndrome
 Autistic Disorder Antibodies  >7 publications with DISC1 and Autistic Disorder
 Asperger Syndrome Antibodies  >5 publications with DISC1 and Asperger Syndrome
 Schizophrenia, Childhood Antibodies  >4 publications with DISC1 and Schizophrenia, Childhood
 Prenatal Exposure Delayed Effects Antibodies  >3 publications with DISC1 and Prenatal Exposure Delayed Effects
 Intellectual Disability Antibodies  >2 publications with DISC1 and Intellectual Disability
 Aneuploidy Antibodies  >2 publications with DISC1 and Aneuploidy
 Chromosome Breakage Antibodies  >2 publications with DISC1 and Chromosome Breakage
 Mitochondrial Diseases Antibodies  >2 publications with DISC1 and Mitochondrial Diseases
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