NP_062111.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
48,106 Da
NCBI Official Full Name
squalene synthase
NCBI Official Synonym Full Names
farnesyl diphosphate farnesyl transferase 1
NCBI Protein Information
squalene synthase; SS; SQS; squalene synthetase; FPP:FPP farnesyltransferase; farnesyl diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase
UniProt Protein Name
Squalene synthase
UniProt Synonym Protein Names
FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase
UniProt Synonym Gene Names
UniProt Entry Name
FDFT_RAT
NCBI Summary for FDFT1
catalyzes the conversion of trans-farnesyl diphosphate to squalene; plays a role in biosynthesis of cholesterol and of isoprenoids [RGD, Feb 2006]
UniProt Comments for FDFT1
Function: Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway.
Catalytic activity: 2 farnesyl diphosphate + NAD(P)H = squalene + 2 diphosphate + NAD(P)+.
Cofactor: Magnesium.
Research Articles on FDFT1
Precautions
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Disclaimer
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Pathways associated with FDFT1 elisa kit
Diseases associated with FDFT1 elisa kit
Organs/Tissues associated with FDFT1 elisa kit
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