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NBN elisa kit :: Rat nibrin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9338916 NBN elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

nibrin (NBN), ELISA Kit

 Also Known As   

Rat Nibrin, NBN ELISA Kit

 Product Synonym Names    Rat Nibrin (NBN) ELISA kit; AT-V1; AT-V2; ATV; FLJ10155; MGC87362; NBS; NBS1; P95; Nijmegen breakage syndrome 1 (nibrin) ; cell cycle regulatory protein p95; p95 protein of the MRE11/RAD50 complex; nibrin
 Product Gene Name   

NBN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9JIL9
 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NBN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NBN purchase    MBS9338916 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the nibrin (NBN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NBN. The ELISA analytical biochemical technique of the MBS9338916 kit is based on NBN antibody-NBN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NBN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NBN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for NBN. It may not necessarily be applicable to this product.
 NCBI GI #    20302036
 NCBI GeneID    85482
 NCBI Accession #    NP_620228.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_138873.2 [Other Products]
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 UniProt Primary Accession #    Q9JIL9 [Other Products]
 UniProt Secondary Accession #    Q5RKL2 [Other Products]
 UniProt Related Accession #    Q9JIL9 [Other Products]
 Molecular Weight    83,150 Da
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 NCBI Official Full Name    nibrin
 NCBI Official Synonym Full Names    nibrin
 NCBI Official Symbol    Nbn [Similar Products]
 NCBI Official Synonym Symbols   
Nbs1
[Similar Products]
 NCBI Protein Information    nibrin; nijmegen breakage syndrome protein 1 homolog
 UniProt Protein Name    Nibrin
 UniProt Synonym Protein Names   
Nijmegen breakage syndrome protein 1 homolog
 Protein Family    Nibrin
 UniProt Gene Name    Nbn [Similar Products]
 UniProt Synonym Gene Names    Nbs1 [Similar Products]
 UniProt Entry Name    NBN_RAT
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 NCBI Summary for NBN    may be involved in regulation of cardiomyocyte proliferation; may act in a complex with MRE11 and RAD50 to play roles in DNA repair, activation of cell cycle checkpoints, and telomere maintenance [RGD, Feb 2006]
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 UniProt Comments for NBN    NBS1: a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome.

Protein type: DNA repair, damage; Cell cycle regulation

Cellular Component: chromosome, telomeric region; PML body; Mre11 complex; nuclear chromosome, telomeric region; nucleolus; replication fork; intracellular; nucleus; nuclear inclusion body

Molecular Function: ATP-dependent DNA helicase activity; damaged DNA binding; protein N-terminus binding; transcription factor binding

Biological Process: response to drug; in utero embryonic development; negative regulation of virion penetration into host cell; mitotic cell cycle checkpoint; regulation of fibroblast proliferation; positive regulation of kinase activity; isotype switching; positive regulation of protein amino acid autophosphorylation; DNA duplex unwinding; cell proliferation; negative regulation of neuron differentiation; meiotic cell cycle; mitotic cell cycle G2/M transition DNA damage checkpoint; double-strand break repair; positive regulation of cell proliferation; DNA damage checkpoint; blastocyst growth; neuromuscular process controlling balance; telomere maintenance
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with NBN elisa kitDiseases associated with NBN elisa kit
 Products by Pathway  Pathway Diagram
 ATM Mediated Phosphorylation Of Repair Proteins Pathway antibodies  ATM Mediated Phosphorylation Of Repair Proteins Pathway Diagram
 ATM Mediated Response To DNA Double-strand Break Pathway antibodies  ATM Mediated Response To DNA Double-strand Break Pathway Diagram
 Assembly Of The RAD50-MRE11-NBS1 Complex At DNA Double-strand Breaks Pathway antibodies  Assembly Of The RAD50-MRE11-NBS1 Complex At DNA Double-strand Breaks Pathway Diagram
 BRCA1-associated Genome Surveillance Complex (BASC) Pathway antibodies  BRCA1-associated Genome Surveillance Complex (BASC) Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 Double-Strand Break Repair Pathway antibodies  Double-Strand Break Repair Pathway Diagram
 Homologous Recombination Repair Pathway antibodies  Homologous Recombination Repair Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Homologous Recombination Repair Of Replication-independent Double-strand Breaks Pathway antibodies  Homologous Recombination Repair Of Replication-independent Double-strand Breaks Pathway Diagram
 Disease Name  Pubmed Publications
 Nijmegen Breakage Syndrome Antibodies  >214 publications with NBN and Nijmegen Breakage Syndrome
 Ataxia Antibodies  >189 publications with NBN and Ataxia
 Neoplasms Antibodies  >185 publications with NBN and Neoplasms
 Nervous System Diseases Antibodies  >80 publications with NBN and Nervous System Diseases
 Breast Neoplasms Antibodies  >57 publications with NBN and Breast Neoplasms
 Skin Diseases Antibodies  >56 publications with NBN and Skin Diseases
 Lymphoma Antibodies  >32 publications with NBN and Lymphoma
 Carcinoma Antibodies  >32 publications with NBN and Carcinoma
 Leukemia Antibodies  >31 publications with NBN and Leukemia
 Anemia Antibodies  >19 publications with NBN and Anemia
Organs/Tissues associated with NBN elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >21 publications with NBN and Brain
 Lung Antibodies  >19 publications with NBN and Lung
 Liver Antibodies  >12 publications with NBN and Liver
 Kidney Antibodies  >7 publications with NBN and Kidney
 Inner Ear Antibodies  >3 publications with NBN and Inner Ear
 Embryonic Tissue Antibodies  >2 publications with NBN and Embryonic Tissue
 Testis Antibodies  >2 publications with NBN and Testis
 Ovary Antibodies  >2 publications with NBN and Ovary
 Pancreas Antibodies  >1 publications with NBN and Pancreas
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