NP_036768.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Related Accession #
Molecular Weight
20,204 Da
NCBI Official Full Name
parathyroid hormone-related protein preproprotein
NCBI Official Synonym Full Names
parathyroid hormone-like hormone
NCBI Official Synonym Symbols
NCBI Protein Information
parathyroid hormone-related protein; PTHrP; PTH-rP; parathyroid-like peptide; parathyroid hormone-like peptide; parathyroid hormone-like protein
UniProt Protein Name
Parathyroid hormone-related protein
UniProt Synonym Protein Names
Parathyroid hormone-like protein; PLP
UniProt Synonym Gene Names
UniProt Entry Name
PTHR_RAT
NCBI Summary for PTHrP
induces vasodilation; may play a neuroprotective role in response to ischemic brain injury [RGD, Feb 2006]
UniProt Comments for PTHrP
PTHrP: a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Three alternatively spliced isoforms have been described.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; extracellular region; intracellular; nucleus
Molecular Function: peptide hormone receptor binding; hormone activity
Biological Process: epithelial cell differentiation; regulation of gene expression; negative regulation of transcription factor activity; negative regulation of chondrocyte differentiation; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; protein processing; regulation of chondrocyte differentiation; skeletal development; surfactant homeostasis; alveolus development; G-protein signaling, adenylate cyclase activating pathway; bone mineralization; osteoblast development; endoderm development; endochondral ossification
Research Articles on PTHrP
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with PTHrP elisa kit
Pathways associated with PTHrP elisa kit
Diseases associated with PTHrP elisa kit
Organs/Tissues associated with PTHrP elisa kit
|