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PDCD4 elisa kit :: Rat programmed cell death 4 (neoplastic transformation inhibitor) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9320293 PDCD4 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4), ELISA Kit

 Also Known As   

Rat Programmed cell death protein 4, PDCD4 ELISA Kit

 Product Synonym Names    Rat Programmed cell death protein 4 (PDCD4) ELISA kit; RP11-348N5.4; H731; MGC33046; MGC33047; nuclear antigen H731; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor)
 Product Gene Name   

PDCD4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9JID1
 Species Reactivity    Rat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PDCD4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PDCD4 purchase    MBS9320293 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the programmed cell death 4 (neoplastic transformation inhibitor) (PDCD4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PDCD4. The ELISA analytical biochemical technique of the MBS9320293 kit is based on PDCD4 antibody-PDCD4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDCD4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDCD4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PDCD4. It may not necessarily be applicable to this product.
 NCBI GI #    21914829
 NCBI GeneID    64031
 NCBI Accession #    NP_071601.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_022265.2 [Other Products]
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 UniProt Primary Accession #    Q9JID1 [Other Products]
 UniProt Related Accession #    Q9JID1 [Other Products]
 Molecular Weight    51,736 Da
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 NCBI Official Full Name    programmed cell death protein 4
 NCBI Official Synonym Full Names    programmed cell death 4
 NCBI Official Symbol    Pdcd4 [Similar Products]
 NCBI Official Synonym Symbols   
Dug
[Similar Products]
 NCBI Protein Information    programmed cell death protein 4; death-upregulated; death up-regulated gene protein
 UniProt Protein Name    Programmed cell death protein 4
 UniProt Synonym Protein Names   
Death up-regulated gene protein
 Protein Family    Programmed cell death protein
 UniProt Gene Name    Pdcd4 [Similar Products]
 UniProt Synonym Gene Names    Dug [Similar Products]
 UniProt Entry Name    PDCD4_RAT
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 NCBI Summary for PDCD4    acts as an inhibitor of apoptosis; has similarity to eukaryotic translation initiation factor (eIF)4G [RGD, Feb 2006]
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 UniProt Comments for PDCD4    PDCD4: protein localized to the nucleus in proliferating cells that seems to possess a tumor suppressor activity. Directly interacts with the RNA helicase eIF4A and inhibits protein synthesis by interfering with the assembly of the cap-dependent translation initiation complex. Suppresses carbonic anhydrase type II protein expression in carcinoid cell lines. Since tumor cells require a high bicarbonate flux for their growth, carbonic anhydrase suppression results in growth inhibition. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two differentially spliced isoforms have been identified.

Protein type: Tumor suppressor; Apoptosis

Cellular Component: nucleoplasm; cytoplasm; nucleus; cytosol

Molecular Function: RNA binding

Biological Process: negative regulation of JNK activity; apoptosis; regulation of protein metabolic process; cell aging; negative regulation of transcription, DNA-dependent; negative regulation of apoptosis
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 Research Articles on PDCD4    1. PDCD4 depletion by RNA interference had no significant effect on phenylalanine incorporation into myotube mixed proteins in control cells but further suppressed (30%) this measure in nutrient-deprived cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PDCD4 elisa kitOrgans/Tissues associated with PDCD4 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >148 publications with PDCD4 and Neoplasms
 Carcinoma Antibodies  >68 publications with PDCD4 and Carcinoma
 Adenocarcinoma Antibodies  >37 publications with PDCD4 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >32 publications with PDCD4 and Cell Transformation, Neoplastic
 Gastrointestinal Diseases Antibodies  >28 publications with PDCD4 and Gastrointestinal Diseases
 Neoplasm Metastasis Antibodies  >26 publications with PDCD4 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >23 publications with PDCD4 and Breast Neoplasms
 Neoplasm Invasiveness Antibodies  >22 publications with PDCD4 and Neoplasm Invasiveness
 Carcinoma, Squamous Cell Antibodies  >17 publications with PDCD4 and Carcinoma, Squamous Cell
 Neoplasms, Experimental Antibodies  >14 publications with PDCD4 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >22 publications with PDCD4 and Lung
 Colon Antibodies  >18 publications with PDCD4 and Colon
 Liver Antibodies  >16 publications with PDCD4 and Liver
 Brain Antibodies  >9 publications with PDCD4 and Brain
 Prostate Antibodies  >8 publications with PDCD4 and Prostate
 Kidney Antibodies  >7 publications with PDCD4 and Kidney
 Heart Antibodies  >7 publications with PDCD4 and Heart
 Pancreas Antibodies  >5 publications with PDCD4 and Pancreas
 Ovary Antibodies  >3 publications with PDCD4 and Ovary
 Thymus Antibodies  >2 publications with PDCD4 and Thymus
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