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PCCA elisa kit :: Rat propionyl Coenzyme A carboxylase, alpha polypeptide ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9334641 PCCA elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

propionyl Coenzyme A carboxylase, alpha polypeptide (PCCA), ELISA Kit

★Popular Item★
 Also Known As   

Rat Propionyl-CoA carboxylase alpha chain, mitochondrial, PCCA ELISA Kit

 Product Synonym Names    Rat Propionyl-CoA carboxylase alpha chain; mitochondrial (PCCA) ELISA kit; RP11-151A6.1; PCCase alpha subunit; pccA complementation group; propanoyl-CoA:carbon dioxide ligase alpha subunit; propionyl-CoA carboxylase alpha chain; mitochondrial; propionyl-Coenzyme A carboxylase; ; propionyl Coenzyme A carboxylase; alpha polypeptide
 Product Gene Name   

PCCA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P14882
 Species Reactivity    Rat
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.625 ng/ml - 20 ng/ml
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PCCA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PCCA purchase    MBS9334641 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the propionyl Coenzyme A carboxylase, alpha polypeptide (PCCA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing PCCA, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9334641 kit is based on PCCA antibody-PCCA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PCCA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PCCA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PCCA elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PCCA (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9334641. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PCCA. It may not necessarily be applicable to this product.
 NCBI GI #    158303308
 NCBI GeneID    687008
 NCBI Accession #    NP_062203.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_019330.1 [Other Products]
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 UniProt Primary Accession #    P14882 [Other Products]
 UniProt Related Accession #    P14882 [Other Products]
 Molecular Weight    81,623 Da
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 NCBI Official Full Name    propionyl-CoA carboxylase alpha chain, mitochondrial
 NCBI Official Synonym Full Names    propionyl CoA carboxylase, alpha polypeptide
 NCBI Official Symbol    Pcca [Similar Products]
 NCBI Protein Information    propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase alpha subunit; PCCase subunit alpha; propanoyl-CoA:carbon dioxide ligase alpha subunit; propanoyl-CoA:carbon dioxide ligase subunit alpha; Propionyl Coenzyme A carboxylase alpha polypeptide; propionyl-coenzyme A carboxylase, alpha polypeptide
 UniProt Protein Name    Propionyl-CoA carboxylase alpha chain, mitochondrial
 UniProt Synonym Protein Names   
Propanoyl-CoA:carbon dioxide ligase subunit alpha
 UniProt Gene Name    Pcca [Similar Products]
 UniProt Synonym Gene Names    PCCase subunit alpha [Similar Products]
 UniProt Entry Name    PCCA_RAT
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 NCBI Summary for PCCA    alpha subunit of propionyl coenzyme A carboxylase, which catalyzes the conversion of ATP, propanoyl-CoA, and HCO3- to ADP, phosphate, and (S)-methylmalonyl-CoA [RGD, Feb 2006]
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 UniProt Comments for PCCA    PCCA: Defects in PCCA are the cause of propionic acidemia type I (PA-1). PA-1 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - propanoate; Ligase; Mitochondrial; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 6.4.1.3

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: enzyme binding; metal ion binding; propionyl-CoA carboxylase activity; biotin carboxylase activity; ATP binding

Biological Process: metabolic process; fatty acid catabolic process; amino acid catabolic process
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 Research Articles on PCCA    1. Methylmalonyl-CoA mutase and PCCA show a much higher expression level in the entire CNS than in the liver, suggesting a different, but important function of this pathway during brain development.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PCCA elisa kitPathways associated with PCCA elisa kit
 Reference Product  PubMed Publications
 Pccb elisa kit  >50 publications with PCCA and Pccb
 Acaa2 elisa kit  >1 publications with PCCA and Acaa2
 Mcee elisa kit  >1 publications with PCCA and Mcee
 Products by Pathway  Pathway Diagram
 2-oxobutanoate Degradation I Pathway antibodies  2-oxobutanoate Degradation I Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Glyoxylate And Dicarboxylate Metabolism Pathway antibodies  Glyoxylate And Dicarboxylate Metabolism Pathway Diagram
 Glyoxylate And Dicarboxylate Metabolism Pathway antibodies  Glyoxylate And Dicarboxylate Metabolism Pathway Diagram
 Propanoate Metabolism Pathway antibodies  Propanoate Metabolism Pathway Diagram
 Propanoate Metabolism Pathway antibodies  Propanoate Metabolism Pathway Diagram
 Valine, Leucine And Isoleucine Degradation Pathway antibodies  Valine, Leucine And Isoleucine Degradation Pathway Diagram
 Valine, Leucine And Isoleucine Degradation Pathway antibodies  Valine, Leucine And Isoleucine Degradation Pathway Diagram
 Superpathway Of Methionine Salvage And Degradation antibodies  Superpathway Of Methionine Salvage And Degradation Diagram
Diseases associated with PCCA elisa kitOrgans/Tissues associated with PCCA elisa kit
 Disease Name  Pubmed Publications
 Propionic Acidemia Antibodies  >51 publications with PCCA and Propionic Acidemia
 Disease Models, Animal Antibodies  >6 publications with PCCA and Disease Models, Animal
 Fatty Liver Antibodies  >5 publications with PCCA and Fatty Liver
 Carcinoma Antibodies  >4 publications with PCCA and Carcinoma
 Adenocarcinoma Antibodies  >4 publications with PCCA and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >4 publications with PCCA and Cardiovascular Diseases
 Liver Diseases Antibodies  >4 publications with PCCA and Liver Diseases
 Atrophy Antibodies  >4 publications with PCCA and Atrophy
 Liver Neoplasms Antibodies  >3 publications with PCCA and Liver Neoplasms
 Seizures Antibodies  >3 publications with PCCA and Seizures
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >11 publications with PCCA and Liver
 Heart Antibodies  >4 publications with PCCA and Heart
 Brain Antibodies  >3 publications with PCCA and Brain
 Placenta Antibodies  >2 publications with PCCA and Placenta
 Muscle Antibodies  >2 publications with PCCA and Muscle
 Embryonic Tissue Antibodies  >2 publications with PCCA and Embryonic Tissue
 Colon Antibodies  >1 publications with PCCA and Colon
 Lung Antibodies  >1 publications with PCCA and Lung
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